Tips for Investigators
The CCTS Biobank recommends best practices from several biospecimen research organizations:
- International Society for Biological and Environmental Repositories (ISBER) Best Practices:
- NCI Office of Biorepositories and Biospecimen Research (OBBR):
- National Biospecimen Network (NBN) Best Practices:
http://biospecimens.cancer.gov/resources/publications/reports/nbn.asp (view the NBN Blueprint at the end of the article)
- Case Studies of Existing Human Tissue Repositories:
"Best Practices" for a Biospecimen Resource for the Genomic and Proteomic Era
- National Bioethics Advisory Commission:
Contact the Biobank Program Coordinator for additional resources and possible updates on topics such as ethics and guidelines; consent issues; DNA collection; sample and data collection and distribution; and genomic research and biobanking.
The CCTS Biobank recommends the Step by Step Start-Up Guide for Registries and Repositories. Created by the online Wiki Advocacy Group, this site asks questions to effectively guide your efforts in building a repository:
- What will you collect?
- How will you collect data and/or samples?
- What else is needed?
We also recommend each investigator take steps to automate data collection and the informed consent process for human subjects by contacting the Biomedical Informatics Component at http://www.uthouston.edu/uth-big/contact+us.htm. BMI is consulting with investigators to assist them with data de-identification; regulatory compliance; developing and implementing databases; modifying existing databases; and electronic consenting of patients.