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Committee For the Protection of Human Subjects

State of Texas Master IRB Reciprocity Agreement

UTHealth has signed the State of Texas Master IRB Reciprocity Agreement, which serves to reduce duplicative IRB reviews. Multi-site studies involving more than one of the participating institutions (listed below) may request to rely on one IRB. You should consider using this agreement any time you are conducting research with any of the participating institutions. Procedures are found below. 

The University of Texas System Participating Institutions:

Other Participating Texas Institutions of Higher Education:

PROCEDURE: If you wish to rely on the IRB from another participating Texas Institution:

  1. UT Houston PI  requests to rely via iRIS
  2. UT Houston CPHS reviews the request and sends a formal permission letter
  3. UT Houston PI  sends documents to lead PI:
  1. Lead PI  submits documents to Reviewing IRB
  2. Reviewing IRB sends approval letter to lead PI.
  3. Lead PI  sends approval letter and stamped documents to UT Houston PI
  4. UT Houston PI  submits approval letter and stamped documents to UT Houston CPHS
  5. UT Houston CPHS issues an Activation Letter

PROCEDURE: If a PI from another participating Texas institution (also called Site PI for the purpose of this policy) wishes to rely on UT Houston's CPHS

  1. Site PI submits permission to rely to their institutional IRB (in some institutions this has been incorporated within the electronic IRB system)
  2. Site PI’s IRB reviews the permission to rely and sends a formal permission letter
  3. Site PI sends documents to UT Houston PI
  1. UT Houston PI  submits documents to CPHS via the Change Request form on iRIS (or along with the other initial review materials depending on the timing)
  2. UT Houston CPHS IRB sends approval letter to UT Houston PI.
  3. UT Houston PI  sends approval letter and stamped documents to Site PI
  4. Site PI  submits approval letter and stamped documents to their own IRB
  5. Local IRB issues an Activation Letter

Links to SOPs related to reciprocity:

Forms: