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Clinical Trials Resource Center

Ongoing Trials at UTHealth

DERMATOLOGIC (SKIN disorders)

  • Psoriasis Study for Adolescents
    A Phase 1, Open-Label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Calcipotriene Foam, 0.005%, Applied Under Maximal-Use Conditions in Adolescent Subjects (Ages 12 to 16 Years) with Plaque Psoriasis
    Coordinator Name: Rhea Elliott
    E-mail: Rhea.e.elliott@uth.tmc.edu
    Phone: 713-500-8280
    Coordinator Name: Maria Lopez
    E-mail: maria.d.lopez@uth.tmc.edu
    Phone: 713-500-8266
    Principal Investigator: Adelaide A. Hebert, MD
    for more information – clinicaltrials.gov

    Target Population: Boys and girls ages 12 to 16 years with psoriasis

  • Psoriasis Study for Children
    A Multicenter, Randomized, Double-Blind, Phase 3 Study of the Safety, Efficacy, Systemic Exposure, and Pharmacodynamics of Calcipotriene Foam, 0.005%, Versus Vehicle Foam in Pediatric Subjects (Ages 2 to 11 Years) with Plaque Psoriasis
    Coordinator Name: Rhea Elliott
    E-mail: Rhea.e.elliott@uth.tmc.edu
    Phone: 713-500-8280
    Coordinator Name: Maria Lopez
    E-mail: maria.d.lopez@uth.tmc.edu
    Phone: 713-500-8266
    Principal Investigator: Adelaide A. Hebert, MD
    for more information - clinicaltrials.gov

    Target Population: Boys and girls ages 2 to 11 years with psoriasis

  • Psoriasis Study for Children
    A Multicenter, Randomized, Double Blind, Parallel Group, Vehicle Controlled Study of the Safety and Efficacy of Calcitriol 3 mcg/g Ointment Applied Twice Daily for 8 Weeks in Pediatric Subjects (2 to 12 Years of Age) with Mild to Moderate Plaque Psoriasis
    Coordinator Name: Rhea Elliott
    E-mail: Rhea.e.elliott@uth.tmc.edu
    Phone: 713-500-8280
    Coordinator Name: Maria Lopez
    E-mail: maria.d.lopez@uth.tmc.edu
    Phone: 713-500-8266
    Principal Investigator: Adelaide A. Hebert, MD
    for more information - clinicaltrials.gov

    Target Population: Boys and girls ages 2 to 12 years with psoriasis

  • Atopic Dermatitis Study for Children
    A Multi-Center, Open Label, Phase 1 Study to Evaluate the Safety of Both MSRD-100 (Fluticasone Propionate) Gel 0.025% and Fluticasone Propionate Cream 0.05% Including its Effects on the Hypothalamic Pituitary Adrenal (HPA) Axis in the Treatment of Atopic Dermatitis in Pediatric Subjects
    Coordinator Name: Rhea Elliott
    E-mail: Rhea.e.elliott@uth.tmc.edu
    Phone: 713-500-8280
    Coordinator Name: Maria Lopez
    E-mail: maria.d.lopez@uth.tmc.edu
    Phone: 713-500-8266
    Principal Investigator: Adelaide A. Hebert, MD

    Target Population: Boys and girls ages 3 months to 6 years

GASTROINTESTINAL / HEPATIC

  • NA

HEALTHY VOLUNTEERS

  • Individual differences in the motivational value of reward cues “Responses to Food and Pictures” (Snack Study)
    Coordinator: Paula Lopez-Gamundi
    E-mail: Paula.LopezGamundi@uth.tmc.edu
    Phone: 713-486-2578
    Principal Investigator: Margaret Wardle, PhD

HEART & VASCULAR

  • ALLSTAR
    Coordinator Name: Deborah Barr
    E-mail: deborah.d.barr@uth.tmc.edu
    Phone: 713-500-6598
    Principal Investigator: H.V. Anderson, MD
    for more information – clinicaltrials.gov

    Study Overview: The ALLSTAR Study will evaluate the Safety and Efficacy of Intracoronary Delivery of Allogeneic Cardiosphere-Derived Cells (Stem Cells) in Patients With an Anterior Heart Attack and Ischemic Left Ventricular Dysfunction.

    Target Population: Patients with previous heart attack (within 1 month – 12 months of study treatment)

  • Century Health
    Coordinator Name: Catey Carter, RN 
    E-mail: catharine.v.carter@uth.tmc.edu 
    Phone: 713-500-5200 
    E-mail: ms.century@uth.tmc.edu 
    Phone: 713-500-5200 
    Principal Investigator: K. Lance Gould, MD
    for more information - clinicaltrials.gov
    or  http://www.uth.tmc.edu/pet/century-study/

  • COAPT Trial
    Coordinator Name: Rhonda Patterson
    E-mail: rhonda.s.patterson@uth.tmc.edu
    Phone: 713-500-6550
    Principal Investigator: Richard Smalling. MD
    for more information – clinicaltrials.gov

    Study Overview: The purpose of the Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for High Surgical Risk Patients (COAPT) Trial is to confirm the safety and effectiveness of the MitraClip System for the treatment of moderate-to-severe or severe functional mitral regurgitation (FMR) in high surgical risk subjects.

    Target Population: Patients with Mitral Valve Regurgitation

  • PARTNER II Trial
    Coordinator Name: Susan Davidson
    E-mail: susan.l.davidson@uth.tmc.edu
    Phone: 713-500-5219
    Coordinator Name: Belinda Metts
    E-mail: belinda.j.metts@uth.tmc.edu
    Phone: 713-500-5219
    Principal Investigator: Richard Smalling, MD
    for more information – clinicaltrials.gov

    Study Overview: The purpose of this research study is to study the safety and effectiveness of the Edwards SAPIEN XT™ Transcatheter Heart Valve (THV) and associated delivery systems (transfemoral, transapical and transaortic), which are intended for use in patients with symptomatic, calcific, severe aortic stenosis.

    Target Population: Patients with severe aortic stenosis

  • The SECRET of CHF
    Coordinator Name: Deborah Barr
    E-mail: deborah.d.barr@uth.tmc.edu 
    Phone: 713-500-6598
    Principal Investigator: Prakash Balan, MD
    for more information – clinicaltrials.gov

    Study Overview: The SECRET of CHF Study will evaluate the short term efficacy and safety of tolvaptan in subjects hospitalized for worsening heart failure who have volume overload and one of the following: renal insufficiency, or hyponatremia or inadequate response to diuretic therapy.

    Target Population: Patients admitted to the hospital with heart failure and volume overload

  • Sentinel Study
    Coordinator Name: Belinda Metts
    E-mail: belinda.j.metts@uth.tmc.edu
    Phone: 713-500-5219
    Principal Investigator: Richard Smalling, MD
    for more information – clinicaltrials.gov

    Study Overview: The Sentinel Study is a randomized controlled trial that will assess the safety and efficacy of the Claret Medical Sentinel Cerebral Protection System used for embolic protection during Transcatheter Aortic Valve Replacement (TAVR) compared to the TAVR standard of care (without embolic protection).

    Target Population: Patients with severe aortic stenosis who are undergoing TAVR

HEMODIALYSIS

  • Heparin-bonded versus Non-heparin-bonded Polytetrafluroethylene Hemodialysis Access Grafts
    Coordinator Name: Samuel Leake
    E-mail: Samuel.S.Leake@uth.tmc.edu 
    Phone: 713-486-5120
    Principal Investigator: Kristofer Charlton-Ouw, MD
    for more information - clinicaltrials.gov

HIV

NA

HYPERTENSION

  • Determination of Genetics in Childhood Onset Hypertension 
    Coordinator Name: Josephine Turner
    Phone: 713-704-4137
    Email: Josephine.Turner@uth.tmc.edu
    Coordinator Name: Cary Warner
    Phone Number: 713-704-3743
    Principal Investigator: Monesha Gupta, MD

LYMPHATIC

  • Lymph Angiography in Normal and Lymphatic Disorders
    Phone: 713-500-3562 
    Coordinator Name: David Kleiman 
    E-mail: David.M.Kleiman@uth.tmc.edu 
    Phone: 713-500-3595 
    Principal Investigator: Eva Sevick, PhD

NEUROLOGIC

  • Aseptic Meningoencephalitis in Adults 
    Coordinator Name: Monika Ruscheinsky 
    E-mail: monika.ruscheinsky@uth.tmc.edu   
    Phone: 713-704-0825 
    Principal Investigator: Rodrigo Hasbun, MD, MPH

  • ASSIST: Acute Stroke and Spleen Size 
    Coordinator Name: Jennifer Garrett, RN
    E-mail: Jennifer.M.Garrett@uth.tmc.edu
    Phone: 713-500-7183 
    Principal Investigator: Sean Savitz, MD

  • Human Epilepsy Project
    Coordinator Name: Kara Kime
    E-mail: Kara.L.Kime@uth.tmc.edu
    Phone: 713-500-7070
    Principal Investigator: Robert Knowlton, MD
    for more information - http://humanepilepsyproject.org/

  • A Prospective, Open-label Study of the Structure and Function of the Retina in Adult Patients with Refractory Complex Partial Seizures Treated with Vigabatrin (Sabril®)
    Coordinator Name: Kara Kime
    E-mail: Kara.L.Kime@uth.tmc.edu
    Phone: 713-500-7070
    Principal Investigator: Jeremy Slater, MD
    for more information - clinicaltrials.gov

  • VNS Therapy Automatic Magnet Mode Outcomes Study in Epilepsy Patients Exhibiting Ictal Tachycardia
    Coordinator Name: Kara Kime
    E-mail: Kara.L.Kime@uth.tmc.edu
    Phone: 713-500-7070
    Principal Investigator: Jeremy Slater, MD
    for more information - clinicaltrials.gov

PSYCHOLOGIC

  • Autism Spectrum Disorders and Symptoms of ADHD 
    Coordinator Name: Rosleen Mansour 
    E-mail: Rosleen.Mansour@uth.tmc.edu 
    Phone: 713-486-2591  
    Principal Investigator: Deborah A. Pearson, PhD
    for more information - clinicaltrials.gov

  • A Double-blind Randomized Placebo-controlled Study of Aspirin and N-acetyl Cysteine as Adjunctive Treatments for Bipolar Disorder Patients
    Coordinator Name: Danielle Spiker
    E-mail: danielle.e.spiker@uth.tmc.edu
    Phone: 713-486-2627
    Coordinator Name: Lindsay Brewer
    E-mail: lindsay.d.harris@uth.tmc.edu
    Phone: 713-486-2527
    Principal Investigator: Jair C. Soares, MD

  • Searching for Endophenotypes of Bipolar Disorder
    Coordinator Name: Danielle Spiker
    E-mail: danielle.e.spiker@uth.tmc.edu
    Phone: 713-486-2627
    Coordinator Name: Lindsay Brewer
    E-mail: lindsay.d.harris@uth.tmc.edu
    Phone: 713-486-2527
    Principal Investigator: Jair C. Soares, MD

  • Deep Brain Stimulation (DBS) Therapy for Treatment Resistant Depression
    Coordinator Name: Danielle Spiker
    E-mail: danielle.e.spiker@uth.tmc.edu
    Phone: 713-486-2627
    Coordinator Name: Lindsay Brewer
    E-mail: lindsay.d.harris@uth.tmc.edu
    Phone: 713-486-2527
    Principal Investigator: Jair C. Soares, MD

  • Pediatric Bipolar Registry
    Coordinator Name: Danielle Spiker
    E-mail: danielle.e.spiker@uth.tmc.edu
    Phone: 713-486-2627
    Coordinator Name: Lindsay Brewer
    E-mail: lindsay.d.harris@uth.tmc.edu
    Phone: 713-486-2527
    Principal Investigator: Jair C. Soares, MD

PULMONARY

  • Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program (PAH QuERI Ext)
    Coordinator Name: Kristi Morin, RN, BSN
    E-mail: Kristi.l.baysinger@uth.tmc.edu 
    Phone: 713-500-6851
    Principal Investigator: Bela Patel, MD
    for more information - clinicaltrials.gov

  • Trial of the Early Combination of Oral Treprostinil With a PDE-5 Inhibitor or ERA in Subjects With Pulmonary Arterial Hypertension (FREEDOM-Ev)
    Coordinator Name: Kristi Morin, RN, BSN
    E-mail: Kristi.l.baysinger@uth.tmc.edu 
    Phone: 713-500-6851
    Principal Investigator: Bela Patel, MD

REPRODUCTIVE

  • NA

SCLERODERMA

  • Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)
    Coordinator Name: Ann Saulino, RN
    E-mail: Ann.R.Saulino@uth.tmc.edu 
    Phone: 713-500-7118
    Additional Contact: Kristi Morin, RN, BSN
    E-mail: Kristi.l.baysinger@uth.tmc.edu 
    Phone: 713-500-6851
    Principal Investigator: Maureen Mayes, MD, MPH
    for more information - clinicaltrials.gov

SLEEP

  • Rapid Eye Movement Sleep Behavior Disorder & Parkinson's 
    Coordinator Name: Vicki Ephron, RN 
    E-mail: Vicki.J.Ephron@uth.tmc.edu 
    Phone: 713-500-7073 
    Principal Investigator: Mya C. Schiess, MD
    for more information - clinicaltrials.gov

SUBSTANCE ABUSE

  • Cocaine Use Treatment Research Studies
    Clinical Trial of Citalopram in Cocaine Dependence
    Coordinator: Jessica Vincent
    E-mail: Jessica.N.Vincent@uth.tmc.edu
    Phone: 713-486-2803
    Principal Investigator: Joy M. Schmitz, PhD
    Cognitive-enhancing DA Medications for Cocaine Dependence
    Coordinator: Jessica Vincent
    E-mail: Jessica.N.Vincent@uth.tmc.edu
    Phone: 713-486-2803
    Principal Investigator: Joy M. Schmitz, PhD
    PPAR Gamma Agonist Treatment for Cocaine Dependence
    Coordinator: Jessica Vincent
    E-mail: Jessica.N.Vincent@uth.tmc.edu
    Phone: 713-486-2803
    Principal Investigator: Ponnada Narayana, PhD

  • PTSD & Substance Use Treatment Study
    Trial of a Novel Treatment for Posttraumatic Stress and Substance Dependence
    Coordinator: Jessica Vincent
    E-mail: Jessica.N.Vincent@uth.tmc.edu
    Phone: 713-486-2803
    Principal Investigator: Anka Vujanovic, PhD

  • Marijuana Study
    Effects of Buspirone on Mood and Attention in Marijuana Users
    Coordinator: Isabela Chapa
    E-mail: Isabela.E.Chapa@uth.tmc.edu
    Phone: 713-486-2794
    Coordinator: Jessica Vincent
    E-mail: Jessica.N.Vincent@uth.tmc.edu
    Phone: 713-486-2803
    Principal Investigator: Scott Lane, PhD

WEIGHT LOSS

  • Text Messaging for Weight Loss in Primary Care Patients
    Coordinator Name: Landrus Burress
    E-mail: Landrus.Burress@uth.tmc.edu
    Phone: 713-500-7904
    Principal Investigator: Kevin O. Hwang, MD
    for more information - clinicaltrials.gov