Career Opportunities


TEXAS THERAPEUTICS INSTITUTE
POST-DOCTORAL POSITIONS in immunology, cancer biology, protein engineering, and antibody drug discovery

We are recruiting multiple postdoctoral fellows with experience in immunology, cancer biology, and/or protein engineering to study cancer antibody drug resistance mechanisms, validate cancer drug targets, and develop antibody-based immunotherapies which include monoclonal and bispecific mabs, antibody drug conjugates (ADC), and antibody-protein fusions. Some of our work was published in competitive peer reviewed journals such as Nature, Cell Metabolism, Clinical Cancer Research, Cancer immunology Research, Nature Communications, JCI Insights, Cell Reports, Plos Pathogens and many others. Qualified individuals should possess 1) the ability to design experiments, interpret and track results, and utilize this information to enable hypothesis generation, and 2) the ability to work in a multidisciplinary team environment with strong communication and writing skills. Applicants should submit a CV, a brief research statement with career goal, and contact information for three references to: Dr. Zhiqiang An at zhiqiang.an@uth.tmc.edu. Visit https://www.txtac.net for more information on Dr. An’s research program. 

UTHealth is an affirmative action, equal opportunity employer.. UTHealth does not discriminate on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status, or any other basis prohibited by law or university policy. EOE/M/F/Disabled/Vet. 


CENTER FOR STEM CELL AND REGENERATIVE MEDICINE
POST-DOCTORAL RESEARCH FELLOW

A postdoctoral position in Dr. Momoko Yoshimoto’s Lab is available in Center for Stem Cell and Regenerative Medicine at Brown Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston.

Projects in the laboratory focus on innate-immune lymphoid cell and hematopoietic stem cell development in the mouse embryo and pluripotent stem cells. For more information on Dr. Yoshimoto’s scientific background, please visit: https://www.uth.edu/imm/faculty/profile?id=5fddecab-f364-4565-b534-2cc9f876007a

The qualified candidate should have a Ph.D. or equivalent degree in Hematology, Immunology, or a related field. The candidate is expected to be highly motivated and productive. The candidate who has experience in primary cell culture, ES cell culture, mouse embryo dissection, Flow Cytometry, Molecular Biology, and bone marrow transplantation assays in mice would be more favorable.

Please contact Dr. Momoko Yoshimoto at Momoko.Yoshimoto@uth.tmc.edu with your C.V. and contact information of three references.

Keywords:

Developmental Hematopoiesis, mouse embryo, hematopoietic stem cell, B-1 cell, hemogenic endothelial cell, lymphoid development

UTHealth is an affirmative action, equal opportunity employer.. UTHealth does not discriminate on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status, or any other basis prohibited by law or university policy. EOE/M/F/Disabled/Vet.


CENTER FOR PRECISION BIOMEDICINE
POST-DOCTORAL RESEARCH FELLOW

A Postdoctoral Fellow position is available immediately to join the Theranostics Laboratory in Institute of Molecular Medicine at the University of Texas Health Science Center at Houston (PI Ali Azhdarinia, Ph.D.). The successful candidate will use image-guided drug delivery strategies to enhance therapeutic outcomes in preclinical cancer models, and have access to cutting edge agents with imaging and therapeutic properties. This position will provide the candidate with an opportunity to lead an interdisciplinary research project that is strongly focused on cancer theranostics and radiation biology. 

Applicants must have a doctoral degree with a major in cell and molecular biology or biochemistry. Experience in cancer biology with a focus on radiation biology is highly desirable. He/she should have excellent writing and presentation skills and be able to work independently in a dynamic team environment. The successful candidate will have a track record of productive research, presentations, and publications, and possess a strong work ethic and organizational skills.

We are fully committed to the career development of the successful candidate, providing a platform for them to launch an independent career. It would be expected that the successful applicant will present data arising from this project at leading international conferences, publish as first author in high impact papers, with help given in the preparation of personal fellowship applications.

To apply, please send a single PDF document containing a letter of application, current CV, one sample publication, and contact information for three references to Dr. Ali Azhdarinia, PhD, at: ali.azhdarinia@uth.tmc.edu.

Mentor: Ali Azhdarinia, Ph.D.

Institution: The University of Texas Health Science Center at Houston, McGovern Medical School, Institute of Molecular Medicine

Key Research Areas: Targeted drug delivery, radiosensitization and radioresistance, molecular imaging, mouse models of cancer

Lab website: https://www.uth.edu/imm/faculty/profile?id=519d17b1-3c57-4dc2-9688-2537dcb810be

UTHealth is an affirmative action, equal opportunity employer.. UTHealth does not discriminate on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status, or any other basis prohibited by law or university policy. EOE/M/F/Disabled/Vet.


CENTER FOR PRECISION BIOMEDICINE
POST-DOCTORAL RESEARCH ASSOCIATE

Applications are invited for a postdoctoral position in proteomics in the Institute of Molecular Medicine, University of Texas Health Science Center at Houston (UTHealth). Ph.D. or equivalent in a related scientific field is required. The lab focuses on development and application of proteomics and other molecular techniques to study cancer and other diseases.

We are seeking candidates who are highly motivated, science-driven, collaborative, and have excellent writing and verbal communication skills to join our research team. An ideal candidate will have a strong background in proteomics, and possess hands-on experience in HPLC and mass spectrometry. Previous experience with bioinformatics, metabolomics, functional genomics, glycobiology, cell culture and biological assays will be considered as additional advantages.

To apply, please email CV, contact information for three references, and a statement of research experience and goals to Dr. Sheng Pan at: proteomics@uth.tmc.edu 

UTHealth is an affirmative action, equal opportunity employer.. UTHealth does not discriminate on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status, or any other basis prohibited by law or university policy. EOE/M/F/Disabled/Vet.


TEXAS THERAPEUTIC INSTITUTE
POST-DOCTORAL POSITION in Medicinal Chemistry

We are looking for postdoctoral fellows with experience in organic chemistry and/or medicinal chemistry. Our lab is focused on the development of novel antibody-drug conjugates (ADCs) for effective cancer treatment in collaboration with immunologists, cancer biologists, and clinicians in the Texas Medical Center (TMC) area and others. We are currently working on (1) chemical synthesis and evaluation of novel chemical linkers for efficient construction of ADCs; and (2) design, synthesis, and in-vitro/in-vivo evaluation of multifunctional ADCs. Read our recent publication in Nature Communications (https://doi.org/10.1038/s41467-018-04982-3) and visit our lab website (https://www.tsuchikamalab.org/) for details. This is a unique opportunity to work at the interface of chemistry and biology, which includes not only chemical synthesis and biological studies, but also cross-disciplinary collaboration with clinical researchers and pharmaceutical industries.

Applicants should be independent, highly motivated individuals with a strong organic chemistry and/or medicinal chemistry background and excellent research qualifications. In particular, we prioritize candidates with experience in enzyme-based and cell-based assays and protein chemistry (protein expression, purification, and modification). Successful candidates must hold a doctoral degree, have an excellent publication record, and demonstrate excellent communication and writing skills.

To apply submit a compiled PDF file including:

  • CV
  • A brief research statement with your career goal
  • A list of publication
  • Contact information for three references

To: Dr. Kyoji Tsuchikama, Kyoji.Tsuchikama@uth.tmc.edu  Please write “Postdoc Application” in the subject of your e-mail.

UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status, or any other basis prohibited by law or university policy. EOE/M/F/Disabled/Vet.


CENTER FOR CARDIOVASCULAR GENETICS

POSTDOCTORAL RESEARCH FELLOW POSITION

A research post-doctoral position is available for an energetic individual with research experience in genomics and/or molecular biology of myocardium.

Interested candidates should email their CV to:   Ali.J.Marian@uth.tmc.edu

UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, gender, sexual orientation, national origin, disability, age or any other basis prohibited by law. EOE/M/D/F/V


CENTER FOR METABOLIC AND DEGENERATIVE DISEASES
POST-DOCTORAL FELLOW-Brain control  of body weight and glucose homeostasis

A postdoctoral position is available immediately at The Institute of Molecular Medicine of The University of Texas Health Science Center at Houston. The position involves studies on central mechanisms of feeding, energy and glucose homeostasis as well as related behaviors. A recent PhD in biology or a related field is required. Highly motivated individuals with experience in brain slice recording are preferred. Projects will be centered on understanding neurocircuitry in the brain controlling energy balance using existing animal models with neuron-specific manipulations. Viral tracing, optogenetic, chemogenetic and in vivo live Ca2+ imaging will be used. Applicant review will begin immediately and continue until the position is filled.

Interested applicants should send a cover letter stating their research interests, a curriculum vitae, and relevant reprints to:

Qingchun Tong, Ph.D.
Institute of Molecular Medicine of McGovern Medical School 
The University of Texas Health Science Center at Houston
1825 Pressler Street
Houston, TX  77030
E-mail: qingchun.tong@uth.tmc.edu 

Lab: www.tong-laboratory.com 

Women and minority candidates are strongly encourage to apply.  This is a security sensitive position.

UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status, or any other basis prohibited by law or university policy. EOE/M/F/Disabled/Vet.


CENTER FOR HUMAN GENETICS
POST-DOCTORAL FELLOW IN HUMAN GENETICS/GENOMICS

An open position for a postdoctoral fellow in human genetics/genomics field is available in the laboratory of Ashish Kapoor at the University of Texas Health Science Center at Houston (UTHealth).

Overview:
The Kapoor lab focuses on understanding the role of variable gene expression driven by non-coding cis-regulatory sequence variation in human disease/trait risk. Although, genome-wide association studies (GWAS) have beyond doubt established a major role for variable gene expression as the basis for trait variation and disease risk, the underlying molecular mechanisms remain largely unknown. We utilize a wide array of genetic, biochemical, cellular, functional genomic, epigenomic and computational approaches to identify the molecular components and the structure of the regulatory apparatus underlying gene expression variation in humans. For more information please visit: https://www.uth.edu/imm/faculty/profile?id=19e3224f-26cc-4a97-8735-27a359e81c9c

Application requirements:
We are seeking a talented and highly motivated individual with a Ph.D. in human genetics, genomics, or other relevant field to join the lab. The candidate must demonstrate scientific productivity, rigor and creativity with a strong publication record in peer-reviewed scientific journals. The candidate must demonstrate initiative and the capacity to conduct independent research. Excellent communication and organizational skills are required. The successful candidate will be leading projects on functional characterization of GWAS signals to understand the molecular basis of observed genetic associations. Individuals with both wet lab and computational/statistical experience are preferred.

Salary and benefits will follow National Institutes of Health and UTHealth guidelines. UTHealth offers limited housing opportunities for postdoctoral fellows and a large number of benefits.

The Kapoor lab is located in the Center for Human Genetics at the Institute of Molecular Medicine, McGovern Medical School, UTHealth. UTHealth is one of the several institutions located at the world-renowned Texas Medical Center. The vast resources within UTHealth and other institutions at the Texas Medical Center make it an ideal place to facilitate the success of projects and provide avenues for collaborations with other laboratories. And the city of Houston is the fourth most populous city in the US and with over 80 diplomatic missions, Houston is also one of the most diverse cities in the US.

How to apply:
Applicants should submit their CV, along with a letter outlining their interests and contact information of three references to ashish.kapoor@uth.tmc.edu with “Genetics/Genomics Postdoc” in the subject line.

UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status, or any other basis prohibited by law or university policy. EOE/M/F/Disabled/Vet.


CENTER FOR HUMAN GENETICS
POST-DOCTORAL FELLOW IN STATISTICAL AND COMPUTATIONAL GENOMICS, HOUSTON, TEXAS

A position at the University of Texas Health Science Center at Houston is available for a Postdoctoral fellow in Statistical and Computational Genomics. The position will provide opportunities for a talented individual interested in working with large-scale genomic data in in a collaborative research setting of international studies on cerebrovascular disease and dementia.

The postdoctoral position will be supported by NIH grants that seek to identify the genetic and epigenetic determinants of cerebrovascular disease and dementia. The project will focus on utilizing whole genome sequence and genome-wide genotype data and DNA methylation array data on several large epidemiologic cohort samples to identify biomarkers influencing risk of disease. As part of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, we are performing integrative analysis of functional omics data, whole genome sequence, and clinical data in population-based cohorts. The successful candidate will be primarily responsible for: (1) computational analyses of whole-genome/exome sequencing datasets and genome-wide SNP array; and (2) computational analyses of DNA methylation array data and their integration with genetic data, with the aim to identify novel mechanisms in neurological diseases.

Responsibilities for this position include: 

1) Study coordination and oversight of study procedures
2) Development and implementation of data analysis plans. In particular, analyze whole genome/exome sequencing and genome-wide SNP array data.
3) Develop and implement algorithms, statistical methods and software to analyze large-scale human sequencing data and DNA methylation array and perform integrative functional analysis.
4) Communication and participation in meetings with collaborators
5) Preparation of manuscripts for publication and grant applications 

Job requirements:

The candidate should have completed a PhD in Statistical Genetics, Computational Biology, Population Genetics/Genomics, Computer Science, or a related discipline, and have experience in the field of complex disease research. The candidate should have expertise in genetics and statistical methods for genome data analysis. Experience with large-scale biological datasets, next-generation sequencing and epigenetic data is advantageous. Strong programming skills in the R language on a Linux environment is required.  The candidate should have demonstrated scientific productivity, have excellent organizational, communication, and problem-solving skills, and have the ability to work, both independently and as part of a multi-disciplinary team.

Interested applicants should forward a CV and a statement of qualifications and research interests for this position, as well as the names and contact information for three professional references.

Myriam Fornage, Ph.D.
Professor of Molecular Medicine and Human Genetics
Laurence and Johanna Favrot Distinguished Professor
Myriam.Fornage@uth.tmc.edu 

UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, gender, sexual orientation, national origin, disability, age or any other basis prohibited by law. EOE/M/D/F/V.


CENTER FOR STEM CELL AND REGENERATIVE MEDICINE

POSTDOCTORAL RESEARCH FELLOW POSITION

A postdoctoral position in Dr. Momoko Yoshimoto’s Lab is available in the Center for Stem Cell and Regenerative Medicine at The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston.

Projects in the laboratory focus on B cell and hematopoietic stem cell development in the mouse embryo and pluripotent stem cells. For more information on Dr. Yoshimoto’s scientific background, please visit:

https://www.uth.edu/imm/profile.htm?id=c93bbd2e-39b2-4e42-8e76-a6715be32c3e

The qualified candidate should have a Ph.D. or equivalent degree in Hematology, Immunology, or a related field. The candidate is expected to be highly motivated and productive. The candidate who has experience in primary cell culture, ES cell culture, mouse embryo dissection, Flow Cytometry, Molecular Biology, and bone marrow transplantation assay in mice would be more favorable. 

Please contact Dr. Momoko Yoshimoto at Momoko.Yoshimoto@uth.tmc.edu with your C.V. and contact information of three references. 

Keywords: Developmental Hematopoiesis, mouse embryo, hematopoietic stem cell, B-1 cell, hemogenic endothelial cell, lymphoid development

UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, gender, sexual orientation, national origin, disability, age or any other basis prohibited by law. EOE/M/D/F/V.


CENTER FOR STEM CELL AND REGENERATIVE MEDICINE

POST DOCTORAL POSITION

A postdoctoral position is available in the laboratory of Dr. Radbod Darabi, at Center for Stem Cell and Regenerative Medicine in University of Texas Health Science Center at Houston. The project is focused on skeletal myogenic differentiation of ES/iPS cells and gene correction of patient cells to be applicable for muscle regeneration.

The areas of laboratory's interests include developmental biology of skeletal muscle progenitors, stem cell biology and regenerative medicine in general. Studies are performed on genetically modified cells or mouse models, and involve the cutting edge approaches, such as cell lineage tracing, gene editing and in vivo experiments.

Hard working fresh PhD graduates and junior postdocs (less than 3 yrs.) who look for a vigorous and dynamic program on stem cell biology are encouraged to apply.

Requirements

  1. PhD degree with experience in stem cell biology, molecular cloning, advanced cell culture, animal modeling and/or bioinformatics.
  2. Fresh PhD graduate or junior postdoc (less than 3 yrs.)
  3. Be able to meet in person for interview and provide a scientific presentation

Please send your cover letter outlining your research interests, curriculum vitae and names (with e-mails) of 3-4 references to Dr. Darabi at Radbod.darabi@uth.tmc.edu 

UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, gender, sexual orientation, national origin, disability, age or any other basis prohibited by law. EOE/M/D/F/V".


TEXAS THERAPEUTICS INSTITUTE

POSTDOCTORAL POSITION IN MICROBIAL NATURAL PRODUCT CHEMISTRY

Job Information

The Microbial Natural Products group within the Institute of Molecular Medicine’s Texas Therapeutics Institute is supervised by Profs. Gerald Bills and Zhiqiang An. Our research is directed towards on the discovery and development of novel antimicrobial agents and their biosynthesis. To achieve this goal, we are currently working on (1) biosynthetic pathways of antifungal natural products; and (2) discovery of new antifungal agents from fungi. We are soliciting highly motivated applicants for a postdoctoral research position in natural product chemistry. Hands-on experience in the areas of secondary metabolite purification (HPLC and other chromatography techniques) and structure determination (NMR and MS data interpretation) is essential. Experience in culturing microorganisms, antimicrobial assays, metabolomics or elucidation of biosynthetic pathways would be highly beneficial. Applicant need to have obtained their Ph.D. to be eligible for the position. Interested individuals should send a cover letter, CV, and the names and contact information for three references. The successful applicant will be selected based on the quality and breadth of their previous research experience, publication record, and potential for scientific growth and development. Applications will be accepted until the position is filled. Completed application packages and questions should be emailed to Prof. Gerald Bills, gerald.f.bills@uth.tmc.edu.

 >>Click here for Dr. Bill's IMM faculty page and/or here for his Google Scholar page.

Houston is the most populous city in Texas and the fourth most populous city in the United States. It offers a diverse and stimulating living environment and world class transportation facilities. The University of Texas Health Science Center at Houston (UTHealth) is the most comprehensive academic health center in Texas. It educates and trains health professionals and biomedical scientists, conducts cutting edge biomedical, behavioral, and population research, and provides both primary and highly specialized medical, dental, and public health care expertise. The laboratory is located on the 6th floor of the M.D. Anderson Cancer Center’s South Campus Research Building 3, in a wing dedicated to UTHealth’s Institute of Molecular Medicine. Other facilities of the Institute of Molecular Medicine are located a short distance away in the Fayez S. Sarofim Research Building.

UTHealth is an EEO/AA employer. UTHealth does not discriminate on the basis of race, color, religion, gender, sexual orientation, national origin, disability, age or any other basis prohibited by law. EOE/M/D/F/V".


TEXAS THERAPEUTICS INSTITUTE

POST-DOCTORAL POSITION (in tumor evasion of antibody immunity)

We are looking for a postdoctoral fellow with experience in tumor microenvironment, cancer biology, antibody engineering, and/or immunology to study the concept that tumor associated proteinases can cause an impairment of IgG function through a limited cleavage in the hinge domain and thereby compromise antibody mediated immunity against cancer. Supported by a grant from CPRIT, the postdoc will establish the prevalence of IgG cleavage in clinical tumor samples followed by defining an anti-hinge antibody approach to “rescue” the functional activity of cleaved anticancer antibodies in vitro and in vivo. Qualified individuals should possess

  • the ability to design experiments, interpret and track results, and utilize this information to enable hypothesis generation;
  • the ability to work in a multidisciplinary team environment with strong communication skills.
  • Applicants should submit a CV, a brief research statement with career goal, contact information and three references to: Dr. Zhiqiang An at Zhiqiang.An@uth.tmc.edu. Visit Dr. An's webpage for more information on his research program.  

>>Click here Dr. Zhiqiang An

The University of Texas is an EO/AA employer. M/F/D/V. This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


TEXAS THERAPEUTICS INSTITUTE
POST-DOCTORAL POSITION (in antibody response to viral infection and vaccination and the development of antiviral antibody therapies)

We are looking for two postdoctoral fellows with experience in virology, antibody engineering, and/or immunology to study the humoral response to viral infection and vaccination. Working closely with Merck Research Laboratories which partially fund the project, the postdoc will play a key role in addressing critical biological questions which will results in the discovery and development of vaccines and antibody therapies with a focus on HCMV and flu. Qualified individuals should possess

  • The ability to design experiments, interpret and track results, and utilize this information to enable hypothesis generation;
  • The ability to work in a multidisciplinary team environment with strong communication skills. Applicants should submit a CV, a brief research statement with career goal,
  • Your contact information and three references to: Dr. Zhiqiang An at zhiqiang.an@uth.tmc.edu. Visit Dr. An's webpage for more information on his research program.  

>>Click here Dr. Zhiqiang An

The University of Texas is an EO/AA employer. M/F/D/V. This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


CENTER FOR METABOLIC AND DEGENERATIVE DISEASES
POST-DOCTORAL POSITION

A postdoctoral position is available in the Dr. Eckel-Mahan lab at the The Brown Foundation Institute of Molecular Medicine ("IMM") within the University of Texas Health Sciences Center in Houston ("UTHealth"). Postdoctoral candidates with extensive experience with metabolic characterization of mouse models and some background in molecular and cell biology is strongly preferred.  Central research interests of the lab include the role of the circadian clock in metabolically healthy and diseased states. The postdoctoral candidate will utilize genomic approaches to study tissue-specific clock response to zeitgebers and manipulations that produce phenotypes mimicking human metabolic disorders. Experimentation centered on understanding the molecular mechanisms underlying tissue-specific clock activity will rely on a myriad of biochemical and molecular techniques. The successful postdoctoral candidate will be part of a larger group of scientists at the Center for Metabolic and Degenerative Diseases (MDD) who use integrative approaches to study metabolic and degenerative disorders.

The City of Houston houses a large and thriving research environment at the Texas Medical Center, which is composed of MD Anderson Cancer Center, UTHealth Sciences Center,and Baylor College of Medicine, among numerous other internationally-recognized research and medical institutions, mostly within walking distance of the IMM.

For further information regarding the advertised position, please contact: Kristin.L.Mahan@uth.tmc.edu. Interested candidates should send a cover letter describing research interests, a resume/CV, and the names and contact information for three references.

The position is open until filled.

The University of Texas is an EO/AA employer. M/F/D/V. This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


CENTER FOR METABOLIC AND DEGENERATIVE DISEASES

POST-DOCTORAL POSITION 

A postdoctoral research position is open for a PhD. with expertise in (1) metabolic characterization of mouse models, and (2) molecular studies of adipose tissue biology and pathology. The project will focus on adipose tissue remodeling during obesity development.

Research focuses:

  • Hypoxia stimulated fibrosis and local inflammation in adipose tissue.
  • Mechanisms by which angiogenic factors stimulate white adipocytes “browning” during early stage of obesity development (healthy expansion).
  • The effects of antiangiogenic action by blocking VEGF-A and/or its receptors in the context of preexisting adipose tissue (unhealthy expansion).
  • Reversibility of adipose tissue fibrosis by MT1-MMP (MMP14) and novel anti-fibrotic therapies for the treatment and prevention of obesity and diabetes.
  • The mechanisms by which MT1-MMT exerts profound pathophysiological effects in preexisted unhealthy fat tissue.

Qualifications: We welcome applications from highly qualified and motivated early-career scientists of all countries who have received a PhD degree within the last three years or who will receive their PhD degree by the start of the recruitment. Previous experience with animal work will be a big plus.   

Please submit personal statement, CV, and three letters of references to:

kai.sun@uth.tmc.edu

Kai Sun, MD, PhD
Assistant Professor
Center For Metabolic and Degenerative Diseases
The Brown Foundation Institute of Molecular Medicine
University of Texas Health Science Center at Houston
1825 Pressler st., Houston, TX 77030
Office: 713-500-3190

Visit our webpage at  -  The Center for Metabolic and Degenerative Diseases 

The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


CENTER FOR CARDIOVASCULAR GENOMICS
POST-DOCTORAL POSITION

A PostDoc Position is available immediately at the University of Texas Health Science Center at Houston (https://med.uth.edu/ibp/ ) in the field of cardiovascular genomics.  Our lab is investigating the genetics and pathogenesis of arrythmogenic cardiomyopathy (AC), the leading cause of sudden cardiac death in young people.  The successful applicant will have experience in both experimental and computational biology.  They will be responsible for performing biochemistry, molecular biology, and cell biology experiments, as well as performing bioinformatic analysis of a range of data types (genome sequencing, RNA-seq, ChIP-seq) to dissect the molecular determinants of the disease.  This position will be jointly supervised by Drs. AJ Marian and Jeffrey Chang.

Qualifications

To join our group, we are looking for highly motivated individuals that have demonstrated scientific productivity, excellent communication skills, and the capacity to conduct independent research.  We are interested in applicants from a range of backgrounds that hold a Ph.D. in Cell Biology, Biochemistry, Genetics, Computer Science, Bioinformatics, or comparable experience.  A background in cardiovascular biology is a plus.  Salary will follow NIH and university guidelines.

To Apply

Please send a CV, a brief statement of research interests, and contact information for three references to Dr. Jeffrey Chang (jeffrey.t.chang@uth.tmc.edu).  IMPORTANT: please include the words "Cardiovascular Genomics Postdoc" in the subject line of the email.

The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


CENTER FOR STEM CELL AND REGENERATIVE MEDICINE
POST DOCTORAL RESEARCH ASSOCIATE 

Center of Stem Cell and Regenerative Medicine in the Brown Foundation Institute of Molecular Medicine at the University of Texas Health Science Center at Houston has a available post doctoral research position developing tissue engineering approaches for spinal cord and traumatic brain injury in collaboration with the Vivian L. Smith Department of Neurosurgery at University of Texas Health Science Center at Houston.  Qualified candidates should have a doctoral degree, strong background and good first-author publications in tissue engineering utilizing stem cells as the cell source. Synthetic matrix preparation and stem cell culture will be required in this position.  Prior experience in material synthesis or processing is desirable but not required. The post doctoral researchers are expected to have strong work ethic, high self-motivation, critical thinking abilities, and excellent organizational and communication skills.

For those interested, please send a CV, contact information of three references, and a brief research statement describing past achievements, skills and research interests to Dr. Laura Smith Callahan at email at: laura.a.smithcallahan@uth.tmc.edu


TEXAS THERAPEUTICS INSTITUTE

Positions for postdoctoral fellows to study novel molecular mechanisms of cancer metastasis are available in Dr. Wenliang Li’s lab at the Institute of Molecular Medicine (IMM) of UTHealth-Houston.

Metastasis is responsible for over 90% of cancer death but its mechanisms are still poorly understood. Research in Dr. Li’s lab is to identify and study novel regulators of cancer metastasis, cancer stem cell, epithelial-mesenchymal transition (EMT), and drug resistance through a unique combination of RNAi/cDNA screens, cancer genomics, molecular cell biology, mouse models and patient specimens. The goals of the research are to gain new knowledge of metastasis and to identify novel cancer drug targets for the development of better therapeutics.

Qualified candidates should have a doctoral degree, strong background and good first-author publications in cancer biology, molecular cell biology, or signal transduction. Prior experience in mouse xenograft models is desirable but not required. The postdoc fellows are expected to have strong work ethic, high self-motivation, critical thinking abilities, excellent organizational and communication skills.

For those interested, please send a CV, contact information of three references, and a brief research statement describing past achievements, skills and research interests to Dr. Wenliang Li at email at: wenliang.li@uth.tmc.edu.

Faculty Profile:
Dr. Wenliang Li

TEXAS THERAPEUTICS INSTITUTE at

UTHealth - Houston
The Brown Foundation Institute of Molecular Medicine
for the Preventative of Human Diseases

1825 Pressler Street
Houston, TX 77030

The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.


TEXAS THERAPEUTIC INSTITUTE, IMM

The Texas Therapeutics Institute (TTI) at the Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, is at the forefront of translation research in identifying drug targets and discovering potential therapeutics for cancer treatment.  Our research is focused on understanding the function and signaling mechanisms of ligand-receptor systems that play fundamental roles in the control of growth, proliferation, and migration of cancer cells as well as the self-renewal and differentiation of cancer stem cells.  Our approach to drug discovery is to generate and validate antibodies against targets that are essential to cancer cell survival and then demonstrate robust efficacy in tumor models.  We are equipped with state-of-the-art facilities and instruments to carry out cutting edge research of in vitro and in vivo studies.  Our faculties are highly experienced and successful in drug discovery and development. 

Post-doctoral positions are available in the laboratories of Drs. Zhiqiang An and Qingyun (Jim) Liu at TTI to study mechanism of signaling transduction of ligand-receptors systems in cancer cells and obtain training in drug discovery and development.   Successful candidates must have received Ph.D. within 2 years in the field of cell biology, cancer biology, pharmacology, or biochemistry with first author publications in leading journals.  They must also have strong skills in molecular biology and tissue culture, and the intellect, creativity, and writing skills to pursue a successful research career in academia or industry.

Interested candidates should email CV and at least one letter of references to qingyun.liu@uth.tmc.edu or to zhiqiang.an@uth.tmc.edu.

FACULTY PROFILES 

Zhiqiang An, Ph.D
Qingyun (Jim) Liu, Ph.D.

TEXAS THERAPEUTICS INSTITUTE at
UTHealth - Houston
The Brown Foundation Institute of Molecular Medicine
for the Preventative of Human Diseases
1825 Pressler Street
Houston, TX 77030

The University of Texas is an EO/AA employer. M/F/D/V.  This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.