The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases

Center for Immunology and Autoimmune Diseases


Rick A. Wetsel, Ph.D., Professor and Director

Irma Gigli, M.D., Emeritus Professor

Yeonseok Chung, Ph.D., Assistant Professor

Scott Drouin, Ph.D., Assistant Professor

Amber Luong, M.D., Ph.D., Assistant Professor

Dachun Wang, M.D., Assistant Professor

Eva Zsigmond, Ph.D., Assistant Professor & Director of Transgenic and Stem Cells Service Unit


Daniel Calame, B.S., MD/PhD, Graduate student (Wetsel Laboratory)

Aleksey Domozhirov, M.S., Research Associate (Manager -Transgenic and Stem Cell Service Unit)

Young Uk Kim, B.S., GSBS Graduate Student (Chung Laboratory)

Hoyong Lim, Ph.D., Postdoctoral Fellow (Chung Laboratory)

John Morales, B.S., Senior Research Asst. (Wetsel Laboratory)

Stacey Mueller-Ortiz, Ph.D., Senior Research Scientist (Wetsel Laboratory)

Joanne Shaw, Ph.D., Postdoctoral Fellow (Luong Laboratory)

Jing Yang, B.S., Research Assistant (Zsigmond Laboratory)

The Hans J. Müller-Eberhard and Irma Gigli Center for Immunology and Autoimmune Diseases is examining the molecular and genetic bases of several different allergic, autoimmune, and infectious diseases involving distinct organs. These studies explore the nature, structure, and function of specific cell membrane receptors and their ligands (activated complement proteins) in modulating immune and inflammatory responses. In concert with the molecular studies, the Center's scientists have engineered mice with specific targeted gene mutations or deletions that are being used as models for human disease. These animal studies have facilitated the identification of key gene products that play significant roles in regulating the immune system as well as contributing to the pathogenesis of human disease. Presently, the Center's research efforts are focused on diseases that affect the lung, skin, and kidney.