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Abhijnan Chattopadhyay, PhD

Abhijnan Chattopadhyay, PhD


Dr. Abhijnan Chattopadhyay is from Kolkata, India and received his B.Sc. in Chemistry in 2005 and his M.Sc. in Biochemistry in 2007, both from the University of Calcutta. He then obtained his PhD from the University of Texas Medical Branch at Galveston in 2013 in Biochemistry and Molecular Biology. He joined UTHealth as a postdoctoral fellow in 2018 and was the recipient of the Victor A. McKusick Postdoctoral Fellowship from the National Marfan Foundation between 2019 and 2021. Dr. Chattopadhyay co-chaired the UTHealth Postdoctoral Association (PDA) Travel Award Committee in 2018-2020.  (


Previous Postdoc Position: The University of Texas Medical Branch

PhD, The University of Texas Medical Branch, 2013

MSc, University of Calcutta, 2007

BSc, University of Calcutta


Dianna M. Milewicz, MD, PhD

Research Description

Dr. Chattopadhyay studies the role of smooth muscle cells (SMCs) and specific genetic mutations in SMCs in the development of atherosclerosis. His research has demonstrated that endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) drives the phenotypic switching of SMCs to a modulated cell expressing inflammatory, fibroblast and stem cell marker genes that significantly increases the atherosclerotic plaque burden. Using multiple mouse and in vitro systems, Dr. Chattopadhyay investigates the underlying mechanisms of atherosclerosis to identify potential therapeutic targets.