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Topic: Alzheimer's

Junjie  Chen

Junjie Chen,

The University of Texas MD Anderson Cancer Center
Department of Experimental Radiation Oncology

My laboratory studies many aspects of DNA damage responsive and DNA repair pathways, which include Radiation-induced DNA damage response (DDR), BRCA1/2 and homologous recombination repair, Replication stress pathway and lesion bypass, Fanconi anemia pathway and interstrand crosslink repair, Spartan/C1orf124/DVC1 and DNA-protein crosslink repair, and more recently the roles of DNA damage response in innate immunity. We also conduct mass spectrometry-based proteomics studies of various signaling pathways involved in tumorigenesis, recently focusing on Hippo/YAP and LBK1-AMPK pathways. In addition, we perform whole genome CRISPR/Cas9 screens to investigate gene-gene and drug-gene interactions involved in cancer development and cancer therapy.

Rotation students are welcome to participate in any of these studies.

PubMed

MDACC Faculty

Junjie Chen Lab

Paul  Schulz

Paul Schulz, M.D.

  • Holder, Rick McCord Professorship in Neurology, McGovern Medical School at UTHealth
  • Director, Dementia and Memory Disorders, McGovern Medical School at UTHealth
  • Director, Dementia Program, Mischer Neuroscience Institute at Memorial Hermann-Texas Medical Center

Paul Schulz, M.D., specializes in diagnosing and treating neuropsychiatric disorders, such as dementia, that may produce cognitive, behavioral or mood symptoms. His research interests include the early diagnosis and prevention of dementia, the treatment of Alzheimer’s, the causes and treatment of frontotemporal dementia, and the neurologic complications of post-traumatic stress disorder. He is affiliated with the Mischer Neuroscience Institute and Memorial Hermann-Texas Medical Center.

Previous Interview: http://abcn.ws/JF0Dsz

Claudio  Soto

Claudio Soto, PhD

  • Professor of Neurology, McGovern Medical School at UTHealth
  • Director, The George P. and Cynthia W. Mitchell Center for Research in Alzheimer’s Disease and Related Brain Disorders, McGovern Medical School at UTHealth

Claudio Soto, Ph.D., specializes in the molecular basis of neurodegenerative diseases associated to the misfolding and brain accumulation of proteins, particularly focusing on Alzheimer’s and prion-related disorders.

Claudio  Soto

Claudio Soto, PhD

  • Professor of Neurology, McGovern Medical School at UTHealth
  • Director, The George P. and Cynthia W. Mitchell Center for Research in Alzheimer’s Disease and Related Brain Disorders, McGovern Medical School at UTHealth

Claudio Soto, Ph.D., specializes in the molecular basis of neurodegenerative diseases associated to the misfolding and brain accumulation of proteins, particularly focusing on Alzheimer’s and prion-related disorders.

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