CeTIR Overview

CeTIR is a part of the Department of Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth) and works in partnership with Memorial Hermann - Texas Medical Center (MH-TMC). CeTIR has designed and implemented as well as participated in a wide variety of studies in trauma, burn and traumatic brain injury. CeTIR’s research activities have directly impacted patient care and have resulted in a reduction in overall mortality from 7.1% to 5.7% despite a 13% increase in admissions and a reduction in mortality related to damage control laparotomies from 18.9% to 7.1%.

Activities include:

  • Partnership with MH-TMC, one of the busiest Level 1 trauma center in the U.S.
  • Access to 7000 trauma admissions annually (~3000 are considered highest activation)
  • Air ambulance services transport approximately 1500 highest activation patients
  • Blood products are available on helicopters
  • Conducted 6 multicenter trials as the Clinical Coordinating Center and/or Data Coordinating Center which included:
  • Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study
  • Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial
  • Prehospital Resuscitation on Helicopter Study (PROHS)
  • Provide research implementation and administration services to faculty, fellows, residents and medical students at UTHealth and the McGovern Medical School
  • Provide educational opportunities for medical students, residents, fellows and junior faculty
  • Support 5 research fellows (3 T32 and 2 postdoctoral research fellows)
  • Support 5 - 10 summer medical students every summer
  • Provide 24/7 personnel coverage for research-related activities, including research sample collection and analysis
  • Ongoing collection of data from all highest activation adult trauma patients admitted to MH-TMC and coordination with MH-TMC trauma registry
  • Participation in more than 80 studies resulting in 526 published manuscripts
    • Studies include:
      • Randomized interventional
      • Prospective observational
      • Retrospective
      • Federally and industry-funded
      • Investigator-initiated and sponsor-initiated
  • Multicenter collaborations with 26 universities and institutions including international
  • Faculty and staff have submitted 19 different patent filing applications resulting in 10 patent applications and 1 copyright registration.
  • Obtained nearly $90 million in federal, state, private, and industry grant and contract funding since September 2008 and have applied for $22.8 million in the current fiscal year.

Contact Information

Center for Translational Injury Research
6410 Fannin Street UPB 1100
Houston, Texas 77030
Tel: 713-500-5479
cetir@uth.tmc.edu