Center for Precision Health

Making healthcare precise

The mission of the Center for Precision Health is to develop, implement and evaluate novel informatics and analytic approaches to advancing precision health, including basic, translational and population research aiming to promote prevention, improve treatment efficacy, and ensure patient safety.

ANNOUNCEMENTS

CPH UPDATES

  1. Selected articles from the 2016 International Conference on Intelligent Biology and Medicine (ICIBM).
  2. CPH welcomes Dr. Luca Giancardo to join as an assistant professor. He was a postdoctoral fellow at the Massachusetts Institute of Technology before joining UTHealth.

  3. CPH welcomes Dr. Han Chen to join as an assistant professor. He was a postdoctoral research fellow in the Department of Biostatistics at Harvard T.H. Chan School of Public Health before joining UTHealth.

  4. CPH congratulates Dr. Peilin Jia for receiving the “New Presidential Collaborative Research Award”.


RESEARCH SEMINAR IN PRECISION MEDICINE AVAILABLE AT THE SCHOOL OF BIOMEDICAL INFORMATICS

Seminar in Precision Medicine will introduce and discuss recent advances, frontier technologies, case studies, and future direction in precision medicine. The topics cover precision medicine, bioinformatics, systems biology, pharmacogenomics, genetics, genomic medicine, study design, methodologies and computational tools.

CPH Seminar: Helping clinicians in the era of precision medicine: Overview of the TREC 2017 Precision Medicine Track
Kirk Robers, Ph.D.
2/16/2018, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Identification of disease genes for rare and undiagnosed disorders through an integrative multi-omics approach
Shan Chen, Ph.D.
2/9/2018, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: The Potential of Traditional Chinese Medicine in Balancing Anti-aging and Anti-tumor
Ying Luo, Ph.D.
2/2/2018, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Representation learning of 3D brain angiograms, an application for stroke research
Seymanur Capoglu
1/19/2018, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Alternative Splicing Links Histone Modifications to Embryonic Stem Cell Fate Decision through Cell Cycle-dependent Mechanisms
Yungang Xu, Ph.D.
1/12/2018, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Exploring Disease Mechanisms using Genetically Regulated Endophenotypes
Hae Kyung Im, Ph.D.
12/8/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Special Seminar: Diffusion MRI of the Brain: Principles and Applications in Neuroscience
Rodrigo de Luis Garcia, Ph.D.
12/4/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Evaluating the Evaluation of Cancer Driver Genes
Rachel Karchin, Ph.D.
12/1/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Post GWAS Schizophrenia Study: What we do now?
Xiangning (Sam) Chen, Ph.D.
11/10/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Special Seminar: Integrative Analysis of Long Noncoding RNA and Transcription in Neural Cell Fate Determination and Spinal Cord Injury
Jiaqian Wu, Ph.D.
11/3/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Special Seminar: Integrating Proteomics with Drug Screen Provides Novel Information Content
Wei Zhao, Ph.D.
10/13/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Special Seminar: Identification of genome-wide non-canonical spliced regions, including IRE1a targeted regions with Read-Split-Fly algorithm
Yongsheng Bai, Ph.D.
10/6/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Using Artificial Intelligence to Plan and Conduct Bioinformatics Analyses
Jeffrey T. Chang, Ph.D.
9/29/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Integrated Analysis of TCGA Genomic Data Reveals Clinically important Subtypes in Ovarian and Endometrial Cancer
Yuexin Liu, Ph.D.
9/22/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Annotating Regulatory Variants for Precision Medicine
Dr. Junwen Wang, Ph.D.
9/15/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

I. CPH Seminar: TissGDB: Tissue specific Gene DataBase in Cancer
Pora Kim, Ph.D.
II. CPH Seminar: Genetic Variants in microRNSA Genes and Targets associated with Cardiovascular Disease risk factors in the African American population
Chang Li, Ph.D.
9/8/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Special Seminar: Match up Nature Products with Cancer Targets in the Era of Precision Medicine
Dr. Wendong Huang, Ph.D.
8/18/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Special Seminar: Privacy-Preserving Sharing and Analyzing Sensitive and Biomedical Data
Dr. Xiaoqian Jiang, Ph.D.
6/30/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX

CPH Seminar: Data-Driven Approaches For Efficient Drug Discovery
Dr. WanKyu Kim, Ph.D.
6/23/2017, 3 p.m., UCT1412, 7000 Fannin St., Houston, TX

CPH Seminar: Using The Blueprint Of the Human Genome To Understand The Causes Of Metabolic Disease
Luca Lotta, Ph.D.
6/1/2017, 12 p.m., UCT1412, 7000 Fannin St., Houston, TX

CPH Seminar: Progression and Subtypes of Prediabetes with Metabolomics Profiling in Starr County Mexican Americans
Jun Goo, Ph.D.
5/5/2017, 12 p.m., UCT1414, 7000 Fannin St., Houston, TX



FACULTY


RESEARCH


The Center for Precision Health designs and conducts research and demonstration projects focusing on the use of state-of-art informatics and analytics coupled with Electronic Health Record (EHR), phenotype and –omics data to advance precision health. The center works in close collaboration with researchers and physician scientists across UTHealth and nationwide. The center is currently developing the following four immediate high priority research areas –

  1. Population-based Genomics for Precision Health will identify novel genes and biomarkers for disease diagnosis, treatment and prevention. Special emphasis will be placed on novel gene discovery and pharmacogenomics.

  2. Cancer Precision Medicine will develop and lead research projects utilizing high throughput technologies to identify actionable mutations so that appropriate molecular targeted therapies can be implemented. The CPH will develop cancer genomic and proteomic analytics projects using cancer -omics and related clinical data.

  3. Translational Bioinformatics programs will be developed at the CPH to translate the discoveries of genomic medicine and other studies to promote patient care. This will include pharmacogenomics to produce new drugs based on clinically relevant mutations, drug repositioning or repurposing and the precise prediction of drug side effects, among other foci.

  4. Smart Clinical Trials will be necessary to save costs, increase efficiency and take into account the characteristics of individual study participants. The CPH will conduct research on the design and implementation of smart clinical trials.

CONTACT


Center for Precision Health
7000 Fannin St.
Suite 820
Houston, TX 77030

Phone.713.500.3627
Fax.713.500.3907
email: Zhongming.Zhao@uth.tmc.edu