Center for Precision Health

Making healthcare precise

The mission of the Center for Precision Health is to develop, implement and evaluate novel informatics and analytic approaches to advancing precision health, including basic, translational and population research aiming to promote prevention, improve treatment efficacy, and ensure patient safety.

MOST RECENT ANNOUNCEMENTS

  1. Data Integration for Machine Learning in Medicine Case Studies in Lung Cancer
    Yang Xie, MD, Ph.D.
    09/14/2018

  2. Data, Data Science and Precision Medicine Workshop, jointed organized by Research Data Coordination Service, Data Science and Informatics Core for Cancer Research, and Center for Precision Health. Invited speakers include Dr. Yidong Chen, UT Health Science Center at San Antonio and Dr. Yufei Huang, UT San Antonio.
    09/07/2018

  3. Ruoji Zhao, a graduate student of CPH faculty Dr. Dung Fang Lee’s lab, and Dr. Lee are one of the Awardees (Mentors) in Dean’s Research Scholarship Award Ceremony, UTHealth McGovern Medical School. Congratulations!
    08/31/2018

  4. CPH welcome several new PhD students: Su Wang, Fangfang Yan, Astrid Manuel. Welcome!
    08/27/2018

  5. CPH faculty Dr. Peilin Jia received an NIDCR/NIH R03 grant, entitled “Deep learning methods to predict the function of genetic variants in orofacial clefts”. Congratulations!
    08/15/2018


RESEARCH


The Center for Precision Health designs and conducts research and demonstration projects focusing on the use of state-of-art informatics and analytics coupled with Electronic Health Record (EHR), phenotype and –omics data to advance precision health. The center works in close collaboration with researchers and physician scientists across UTHealth and nationwide. The center is currently developing the following four immediate high priority research areas –

  1. Population-based Genomics for Precision Health will identify novel genes and biomarkers for disease diagnosis, treatment and prevention. Special emphasis will be placed on novel gene discovery and pharmacogenomics.

  2. Cancer Precision Medicine will develop and lead research projects utilizing high throughput technologies to identify actionable mutations so that appropriate molecular targeted therapies can be implemented. The CPH will develop cancer genomic and proteomic analytics projects using cancer -omics and related clinical data.

  3. Translational Bioinformatics programs will be developed at the CPH to translate the discoveries of genomic medicine and other studies to promote patient care. This will include pharmacogenomics to produce new drugs based on clinically relevant mutations, drug repositioning or repurposing and the precise prediction of drug side effects, among other foci.

  4. Smart Clinical Trials will be necessary to save costs, increase efficiency and take into account the characteristics of individual study participants. The CPH will conduct research on the design and implementation of smart clinical trials.

CONTACT


Center for Precision Health
7000 Fannin St.
Suite 820
Houston, TX 77030

Phone.713.500.3627
Fax.713.500.3907
email: Zhongming.Zhao@uth.tmc.edu