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Researchers under this theme focus on the anatomical, biochemical, molecular and behavioral aspects of traumatic injury of the nervous system and neurodegenerative disorders, with the ultimate goal of improved therapies. Neurodegenerative disorders include Alzheimer’s Disease and Other Dementias, Parkinson’s Disease and Other Movement Disorders (including Huntington’s disease, Ataxias, Dystonia), Tauopathies, Tau-dementias, Prion diseases, and Neuromuscular Diseases. Injury from Ischemia, Stroke, Brain and Spinal Cord Trauma, as well as the roles of Neurotoxicity, Inflammation, and Neuroprotection are also examined with relation to trauma and injury. General Brain Wellness and Aging are included under this theme as well.