NABI-Con 25
Join us as we gather like-minded experts to discuss translational therapeutics and major impediments to advancement.
- April 30—May 2, 2025
Goals of the Novel Treatments for Acute Brain Injury (NABI) Institute
To improve the lives of patients who have suffered from acute brain injury through novel therapeutics.
Conference Goals
To facilitate the advancement of novel agents for treating acute brain injury by gathering experts across basic science, clinical practice, and product innovation to focus the group’s combined expertise on specific problems and opportunities leveraging clinical translational research.
Location:
The Westin Houston Medical Center/Museum District
1709 Dryden Rd, Houston, TX 77030
The Westin check-in is on the 5th floor. Please go up the elevators to the lobby. The conference will be held on the 5th floor in Azure III. Parking at the hotel will be validated.
Thursday Dinner Information:
Sixty Vines, Rice Village
2540 University Blvd, Houston, TX 77005
Sixty Vines is a 1-mile walk or quick Uber away from the Westin.
Parking is available in the 2-hour complimentary parking garage or at street level.
Conference Agenda
| Time | Topic | Speaker/Facilitator |
|---|---|---|
| 5:00–6:00 PM | Kick-off / Intros / Welcoming | H Alex Choi, Caitlin Morse |
| NA | Cocktail hour, Introduction | NA |
| 6:00–7:15 PM | Dinner service | NA |
| 6:30 PM | What is with this conference? And connections with TSR | H Alex Choi |
| 6:45 PM | Why has translation been so difficult? | Jarek Aronowski |
| 7:00 PM | Why have we been unsuccessful and what do we need to do differently? | R Loch MacDonald |
| 7:15 PM | How should we be pursuing novel treatments? | James C Grotta |
| 7:30 PM | Dessert & Drinks + Q&A interviews with speakers | H Alex Choi, Caitlin Morse |
| Time | Topic | Speaker/Facilitator |
|---|---|---|
| 7:30 AM | Breakfast | NA |
| 8:00–9:50 AM | AIS / Delirium / Sepsis | (Choi / Pouya) |
| 8:00 AM | New trial of dual sequential doses of TNK for AIS | James C Grotta |
| 8:10 AM | Hypothermia for stroke? | Neeraj Badjatia |
| 8:20 AM | Multi-omic modeling to define therapeutic targets for LVO | Keith Pennypacker |
| 8:30–9:00 AM | Discussion (30 mins) | NA |
| 9:00 AM | IL-6 trans- and classical signaling pathways in delirium | Shouri Lahiri |
| 9:10 AM | Extracorporeal Autocatalytic Hemoperfusion Therapy for Severe Sepsis | Han Gil Jeong |
| 9:20 AM | Creating Dynamic Maps of the Stroke Microenvironment | Neil Nadkarni |
| 9:30–9:50 AM | Discussion (20 mins) | NA |
| 9:50–10:00 AM | Break – Snacks / Refreshments | NA |
| 10:00–12:10 AM | SAH | (Chung / McBride) |
| 10:00 AM | scRNAseq for peripheral immune response in acute brain injury | Dong-wan Kim |
| 10:10 AM | SAH transcriptomics data and the molecular heterogeneity it reveals | Boryana Stamova |
| 10:20 AM | Lipidomic in SAH | Aaron Gusdon |
| 10:30–11:00 AM | Discussion (30 mins) | NA |
| 11:00 AM | Thromboinflammation as a therapeutic target for SAH | Devin McBride |
| 11:10 AM | Innate inflammation in the meninges in DCI after SAH | Javier Provencio |
| 11:20 AM | Microglial signaling in SAH | Khalid Hanafy |
| 11:30 AM | Regulating leukocyte trafficking into the brain to prevent secondary injury | Prajwal Ciryam |
| 11:30 AM–12:10 PM | Discussion (40 mins) | (Cho / Jha) |
| 12:10–1:30 PM | Lunch | Phagenesis, Serb |
| Time | Topic | Speaker/Facilitator |
|---|---|---|
| 1:30–2:50 PM | Novel Devices | (Chung / Morse) |
| 1:30 PM | Brain-ECMO Interaction / New ECMO system | Sung Cho |
| 1:40 PM | Intracranial Compliance of the Injured Brain | Caitlin Morse |
| 1:50 PM | Targeting PSH for Transcutaneous Vagal Nerve Stim after TBI | Jamie Podell |
| 2:00 PM | Portable Brain Imaging | Christian Wight |
| 2:10–2:50 PM | Discussion (40 mins) | NA |
| 2:50–3:10 PM | Break – Snacks / Refreshments | NA |
| 3:10–5:00 PM | TBI and ICH | (Provencio / McBride) |
| 3:10 PM | Acid-base status as a risk factor for spreading depolarization in TBI | Britta Linquist |
| 3:20 PM | Precision Medicine and Host Response in Acute Brain Injuries | Ruchira Jha |
| 3:30 PM | Targeting ferroptosis in traumatic brain injury | Aditya Kumar |
| 3:40–4:10 PM | Discussion (30 mins) | NA |
| 4:10 PM | Laboratory/transfusion medicine approaches in intracerebral hemorrhage | David Roh |
| 4:20 PM | Anti-NdespR as a target for perihemtomal edema | Charlene Ong |
| 4:30–4:50 PM | Discussion (20 mins) | NA |
| 4:50–5:00 PM | Session Close | H Alex Choi |
| 6:30 PM | Dinner – Sixty Vines (2540 University Blvd, Houston, TX 77005) | NA |
| 7:00 PM | Successful commercialization of a product into the NeuroICU | Bill Worthen |
| 7:30 PM | Challenges of bringing new products to market in the NeuroICU | Chad Hoskins |
| 8:00 PM | Roundtable interview | Bill Worthen, Chad Hoskins, Stephan Mayer Moderated by H Alex Choi, Caitlin Morse, David Chung |
| Time | Topic | Speaker/Facilitator |
|---|---|---|
| 7:30 AM | Breakfast | NA |
| 8:20–9:50 AM | Coma and Neuromonitoring | (Morse / Busl) |
| 8:20 AM | Neuromonitoring to detect markers of pathology in coma | Imad Khan |
| 8:30 AM | Dynamic cerebrovascular changes after acute brain injury | Pouya Tashli Fahadan |
| 8:40 AM | Multiomics reverse translation of medical imaging | Paul Nyquist |
| 8:40–9:10 AM | Discussion (30 mins) | NA |
| 9:10 AM | Brain structural connectivity changes after hypoxic ischemic brain injury | Ona Wu |
| 9:20 AM | How are we going to cure coma? | David Chung |
| 9:30–9:50 AM | Discussion (20 mins) | NA |
| 9:50–10:10 AM | Break – Snacks | NA |
| 10:10–11:10 AM | Clinical Trials | (Chung / Badjatia) |
| 10:10 AM | Strive On Trial Results | H Alex Choi |
| 10:20 AM | Practical lessons learned (and continuing to learn) from our SAH trial | Katharina Busl |
| 10:30 AM | Clazosentan and the Future of Pharmacotherapy for Vasospasm | Stephan Mayer |
| 10:40–11:10 AM | Discussion (30 mins) | NA |
| 11:10–12:00 AM | Additional/Future Directions / Closing Remarks | H Alex Choi |