Skip Navigation and Go To Content
Quicklinks
Give

Equipment

Explore this Section
Explore this Section
Explore this Section
Explore this Section

Instrumentation:

  • Titan Krios G3 (300 keV X-FEG, ThermoFisher Scientific) cryo-TEM
    • BioQuantum Energy Filter with K2 Summit direct detector (to be upgraded to BioContinuumHD Imaging Filter with K3 camera in early 2026)
    • Volta Phase Plate
    • 12-position cryo-sample autoloader
    • Automated data collection through EPU, Tomo, and SerialEM
  • BioContinuumHD Imaging Filter with K3 Camera (Gatan) — Coming Soon
    • Energy-filtered direct detection for high-contrast imaging and tomography
    • 94-megapixel super-resolution mode at 1502 frames per second
    • EELS and EFTEM data acquisition options
    • Real-time GPU-based motion correction
  • TFS Glacios F30 (200 keV X-FEG, ThermoFisher Scientific) cryo-TEM
    • Falcon 4i
    • Selectris Energy Filter
    • 12-position cryo-sample autoloader
    • MicroED
    • Automated data collection through EPU, Tomo, and SerialEM
  • Talos Transmission Electron Microscope (TEM, ThermoFisher Scientific) — Coming Soon
    • 120 kV instrument for negative stain EM and cryo-TEM
    • 4K × 4K CETA CMOS camera
    • Routine negative stain imaging for rapid sample screening
    • Tomography and preliminary structural analysis
  • SingleParticle GPU Workstation — Coming Soon
    • Dual Intel Xeon processors, 1 TB ECC memory
    • Four NVIDIA RTX PRO™ 6000 Blackwell GPUs (96GB each)
    • Pre-installed cryo-EM software: RELION, cryoSPARC, Scipion, DeepEMhancer, and more
  • Ancillary equipment for cryospecimen preparation
    • FEI Vitrobot (Mark IV)
    • Leica EMGP
    • Manual plungers
    • Glow Discharging
    • Carbon Coating

Acknowledging Cryo-EM Core

Any use of the resources at UTHealth Cryo-EM Core Facility requires acknowledgement of the resources in publications and presentations.

Any work taking place on the Glacios has to acknowledge NIH S10ODO32204 grant. 

Example: Cryo-EM work (or Some of this cryo-EM work) was performed at the Cryo-EM Core Facility supported by the UTHealth Structural Biology Imaging Center at Houston and by grant from the NIH Office of the Director (1S10OD032204).  Titan Krios G3 subsidized by CPRIT Core Facility Award RP190602 was used for cryo-EM data acquisition in this work.