Prospective Postdocs

Open Postdoc Positions

Resources for Postdocs


Contact Us

UTHealth
Office of Postdoctoral Affairs
6431 Fannin St. - Suite MSE R256
Houston, TX 77030

E-mail: ms.opa@uth.tmc.edu 

Telephone: +1 713 500 6612

Directions to the Office

Available Postdoc Positions

Position Descriptions and Contact Information are provided below. Click on a position title to reveal the detail.

If interested in any of these positions, please apply directly to the contact provided. Please do not send your applications to the Office of Postdoctoral Affairs.

  • Anesthesiology - Adipose Biology and Metabolism Research

    Postdoctoral Position in Adipose Biology and Metabolism Research

    A federally funded, fully supported postdoc position is immediately available in the Department of Anesthesiology, Center for Perioperative Medicine, at the McGovern Medical School of the University of Texas Health Science Center at Houston. The proposed starting date for this position is 09/01/2021.

    Overview:

    The An Laboratory is aiming to carry out paradigm-shifting research in the fields of obesity, diabetes, and metabolism by defining the fundamental mechanism of obesity and bringing treatments fighting obesity and its related metabolic diseases. As a joining faculty member in UT Health, Dr. An has been first-authored and co-authored 35 papers in prestigious journals, including Nature Metabolism, J Hepatology, eLife, Diabetes, Science, Cell Metabolism, etc. His papers have received more than 1,500 citations with an H-index of 19.

    One of the major lab research programs is to increase our understanding of intercellular and interorgan communication during mitochondrial distress using molecular and biochemical methods, primarily cultured cells, genetically engineered mouse models, and human adipose tissue samples. For more information please visit: https://www.anlaboratory.com/.

    We are seeking a talented, enthusiastic, and highly motivated postdoc researcher to join our newly emerging group. By utilizing established mouse models, together we will be uniquely positioned to perform four levels of studies: to explore intracellular regulation and defensive mechanisms against mitochondrial dysfunction, to identify intercellular crosstalk between adipocytes and adipose stromal cells, to discover inter-tissue communication between white and brown adipose tissue, and finally, to investigate the interorgan crosstalk between adipose tissue and liver and other metabolic organs.

    Application Requirements:

    • A Doctorate degree in Biomedical Science or Medicine is required.
    • The candidate is complying with ethics standards in conduct of research.
    • The candidate must demonstrate initiative and the capability to conduct independent research. Strong written and verbal communication and organization skills are required.
    • The candidate is expected to independently perform mouse studies including managing, handling, metabolically assaying, and manipulation of mice and collection of animal tissue samples; to perform primary cell culture and relevant ex vivo or in vitro assays (stromal vascular fraction isolation and differentiation skill and primary hepatocyte isolation and culture skill are highly preferred); to perform flow cytometry for inflammatory phenotyping; to perform molecular and cellular biology assays, such as DNA, RNA and protein isolation, Western blotting, real-time PCR, transcription reporter assays, immunofluorescence and immunohistochemistry assays, from animal tissue samples and cultured cells.
    • Review scientific literature to define specific problems and possible solutions.
    • The candidate is expected to be desire to learn and establish novel methods and assays.
    • Compile, analyze and evaluate data independently.
    • Draft manuscripts for submission to peer-reviewed journals.
    • Experience in submitting or writing grants is preferred.

    How to apply:

    Please send a current resume/CV, a cover letter and contact information of three references to: Yanyu.Wang@uth.tmc.edu, and please copy to Yu.An@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Anesthesiology - Hypoxia Response and Organ Protection

    Postdoc Positions in Hypoxia Response and Organ Protection

    Two federally funded, fully supported postdoc positions are immediately available in the Department of Anesthesiology, Center for Perioperative Medicine, at the McGovern Medical School of the University of Texas Health Science Center at Houston.

    Overview

    The Eltzschig laboratory is interested in studying endogenous adaptive pathways that are under the control of hypoxia-inducible factors. These molecular concepts have been applied to a wide range of disease models that are important for the field of anesthesiology, critical care, and perioperative medicine, including acute lung injury, myocardial or hepatic ischemia, acute kidney injury, and intestinal inflammation. It is hoped that these studies contribute to novel pharmacologic approaches to prevent or treat acute organ injury in surgical patients. For more information please visit: https://med.uth.edu/anesthesiology/faculty/holger-eltzschig-md-phd/ 

    We are seeking two talented and highly motivated postdoc fellows to join the lung and heart groups. The research in the lung group focuses on understanding the inflammatory responses in acute lung injuries. Our recent studies of lung injuries focus on investigating the role of hypoxia-inducible factors (HIFs) and microRNAs in the underlying mechanisms of ALI. The heart group is interested in understanding cardio-protective mechanisms and targets during the Myocardial Ischemia/Reperfusion (IR) injury. Our recent studies showed that changes in metabolic supply and demand lead to the stabilization of hypoxia-inducible transcription factors during myocardial ischemia, resulting in upregulation of cardio-protective small molecules.

    Application Requirements:

    • The candidate must have a Doctorate degree in Basic Science or Medicine.
    • The candidate must demonstrate initiative and the capability to conduct independent research. Strong written and verbal communication and organization skills are required.
    • Review scientific literature to define specific problems and possible solutions.
    • Establish novel methods to test scientific problems.
    • Perform experimental models related to handling and manipulation of mice and collection of animal tissue samples; Perform cell culture and relevant in vitro assays; Perform molecular and cellular biology assays, such as DNA, RNA and protein isolation, Western blotting, real-time PCR, transcription reporter assays, immunofluorescence and immunohistochemistry assays, from animal tissue samples and cultured cells.
    • Compile, analyze and evaluate data independently.
    • Draft manuscripts for submission to peer-reviewed journals; have experience in submitting or writing grants.

    How to apply

    Please send a current resume/CV, a cover letter and contact information of three references to:

    Dr. Yanyu Wang, 6431 Fannin St., University of Texas McGovern Medical School, Department of Anesthesiology, Houston, TX 77030

    Or email to Yanyu.Wang@uth.tmc.edu

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Biochemistry and Molecular Biology - Circadian Rhythms

    Postdoctoral Fellow Positions at UT Health Science Center at Houston, TX, USA

    Two federally-funded, full-time postdoctoral fellow positions are immediately available in the Department of Biochemistry and Molecular Biology at the University of Texas Health Science Center at Houston, USA.

    The major research interests of our lab (https://med.uth.edu/bmb/faculty/zheng-chen-phd/ ) include circadian rhythms, metabolic aging and neurodegenerative diseases. In one major area of research, we previously identified clock-modulating compounds and demonstrated a role of circadian enhancement against metabolic disease and aging (Proc Natl Acad Sci U S A. 2012, 109:101; Cell Metab. 2016, 23:610; Nat Commun. 2019, 10:3923). Moving forward, we aim to deepen our investigation into the regulatory function of circadian rhythms (including sleep cycles) in aging and age-related diseases such as Alzheimer’s Disease. We will employ an integrative approach, combining molecular/cellular methodologies, mouse models, and unique pharmacological reagents. Circadian regulation in aging is an exciting new field, and success in these studies will have profound basic and translational impact.

    Highly motivated candidates with a Ph.D. or an equivalent degree, preferably recently obtained, are encouraged to apply. The ideal candidate should have a demonstrated publication record and solid background in one or more of the following areas, including molecular/cell biology, mouse models and/or neurodegenerative diseases. However, all candidates will be considered. Competitive salary/benefits in line with NIH standards will be offered based on qualification.

    The successful applicant will be working in a highly active research department at McGovern Medical School located within the renowned Texas Medical Center (TMC). The city of Houston also offers a comfortable lifestyle and ample career opportunities. To apply, please email a cover letter, CV, and names and contact information of three referees to Prof. Jake Chen (zheng.chen.1@uth.tmc.edu).

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Biochemistry and Molecular Biology - Circadian Rhythms and Neurodegenerative Diseases

    Postdoctoral Fellow Positions at UTHealth Science Center at Houston

    Federally funded, full-time postdoctoral fellow positions are immediately available in the Department of Biochemistry and Molecular Biology at the University of Texas Health Science Center at Houston, USA. The major research interests of our lab include circadian rhythms and neurodegenerative diseases. In one major area of research, we previously identified core clock gene FBXL21 (Cell. 2013 Feb 28;152(5):1091-105. doi: 10.1016/j.cell.2013.01.055. Cell Rep. 2020 Sep 15;32(11):108140. doi: 10.1016/j.celrep.2020.108140). Moving forward, we aim to deepen our investigation into the regulatory function of circadian rhythms in oligodendrocyte and glia and clock-related diseases such as Alzheimer’s Disease. We will employ an integrative approach, combining molecular/cellular methodologies, mouse models, cutting edge imaging techniques. Circadian regulation in glia and OL is an exciting new field, and success in these studies will have profound basic and translational impact.

    Highly motivated candidates with a Ph.D. or an equivalent degree, preferably recently obtained, are encouraged to apply. The ideal candidate should have a demonstrated publication record and solid background in neuroscience areas. Working experience with laboratory mice is desirable. The candidate should also be proficient with English, and have the personality and professionalism to work productively in a team setting. However, all candidates will be considered. Competitive salary/benefits in line with NIH standards will be offered based on qualification.

    The successful applicant will be working in both UTH and collaborator’s lab at Baylor College of medicine closely located within TMC. The city of Houston also offers a comfortable lifestyle and ample career opportunities. To apply, please email a cover letter, CV, and names and contact information of three referees to Prof. Seung-Hee Yoo (seung-hee.yoo@uth.tmc.edu).

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Biochemistry and Molecular Biology - Role of DHHC proteins in immune system regulation

    Postdoctoral Position at UT Health – IMMUNOLOGY

    A postdoctoral fellow position is immediately available in McGovern Medical School at the University of Texas Health Science Center in Houston, Texas. We are looking for a highly motivated researcher with a with a strong background in cellular and molecular immunology, and previous hands-on experience with mouse models of immunological diseases to study the role of DHHC protein palmitoyl transferases in regulation of the immune system. The goal of our laboratory is to introduce a novel family of regulatory enzymes into the canonical T cell signaling pathway and identify the DHHC family of enzymes as a promising therapeutic target in diseases associated with altered immune system homeostasis.

    Requirements:

    • PhD or equivalent degree;
    • Background in immunology;
    • Prior experience with mouse models of immunological diseases;
    • Knowledge of cellular and molecular biology techniques, proficiency in basic immunology techniques.

    To apply:

    Please send a cover letter, CV and contact information of three references to Askar Akimzhanov, PhD (Askar.M.Akimzhanov@uth.tmc.edu).
    (Please use the subject line “Postdoc in Akimzhanov Lab” in your email.)

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Biochemistry and Molecular Biology - Structure and Function of Ligand-gated Ion Channels

    Two Postdoctoral Research Fellow openings:

    Two NIH-funded postdoctoral positions are available in the laboratory of Dr. Vasanthi Jayaraman (https://med.uth.edu/bmb/faculty/vasanthi-jayaraman-phd/) to study the structure and function of ligand-gated ion channels. The lab uses a multidisciplinary approach, combining single-molecule fluorescence, cell-based fluorescence imaging, structural biology, and electrophysiology.

    Qualifications:

    Candidates should have experience in one or more of the above methods and have recently received their Ph.D. or expect to complete their degree within a year and have a demonstrated record of publications.

    Jayaraman Lab:

    The lab offers rich interdisciplinary training, a highly collegial environment, and mentoring that will allow for the postdoctoral fellows to develop as independent scientists, and successfully transition to positions in academia and industry. The lab has been very successful in helping postdoctoral fellows obtain independent fellowships and with K99/R00 awards for those interested in transitioning to faculty positions.

    To apply:

    Please send your CV, a brief statement of interest, and contact information for 3 people who can provide letters of reference to Prof. Vasanthi Jayaraman (Vasanthi.jayaraman@uth.tmc.edu). Please use the subject line “Postdoc in Jayaraman Lab” in your email.

     

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Biochemistry and Molecular Biology- Structure of a Bacterial Metabolic Pacemaker

    Postdoctoral Position - Structure of a bacterial metabolic pacemaker

    A postdoctoral position newly funded by NIH is available immediately in the laboratory of Dr. Lei Zheng, Department of Biochemistry and Molecular Biology, University of Texas Health Science Center at Houston McGovern Medical School. The fellow will study the structure of a membrane phosphatase protein acting as a novel bacterial metabolic pacemaker. The project involves X-ray crystallography, single-particle cryo-electron microscopy, and fluorescence spectroscopy. 

    The ideal candidate should have a recent Ph.D. in structural biology and biochemistry with demonstrated experience in protein expression, purification and characterization. Experience with membrane protein will be a great asset.  Candidates with a strong background of microbiology who are interested in structural biology are also welcome to apply.

    The laboratory is located in Texas Medical Center, the largest campus for medical research in the world, which provides outstanding environments and opportunities for academic development.  Houston is a highly culture-diversified city with affordable living costs. Salary will be based on NIH standard and individual experience.

     To Apply

    Applicants should send their CV and the names of three references to Dr. Lei Zheng (lei.zheng@uth.tmc.edu).

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • BRAINS Research Lab- Cerebrovascular imaging in neurodegenerative diseases

    Cerebrovascular imaging in neurodegenerative diseases

    UTHealth BRAINS research lab is looking for a postdoctoral fellow or research scientist to join a dynamic research team focused on the function of the blood-brain barrier in both normal brains as well as models of neurodegenerative disorders including Alzheimer’s disease, cerebral amyloid angiopathy, and neurodegenerative lysosomal storage.

    Current projects are developed around intravital two-photon microscopy imaging of cerebrovasculature in brain aging and neurodegeneration. Future work includes the integration of vascular mechanosensing and neuroimmunology with cytokine/chemokine stimulations in aging and disease progression.

    This position is an NIH Research grant funded position. The laboratory is fully equipped with a custom-build two-photon laser-scanning microscope with imaging and stimulation laser lines and primary cell culture equipment. The lab is a part of the UTHealth BRAINS research laboratories and the Graduate Program in Neuroscience. These entities form a vibrant research community.

    Applicants should have experience in quantitative optical methods in vivo and in vitro, contemporary molecular/biochemical analyses, neuroimmunology and/or behavioral neuroscience. 

    Self-motivated and independent applicants are encouraged to apply for the position and after an initial application are expected to include 3 letters of reference.  Salary and stipends are commensurable with experience and granting standards in UTHealth. The position is available immediately.

    All application materials should be sent electronically to:

    Aki Urayama, PhD

    Associate Professor

    Department of Neurology

    University of Texas Medical School at Houston

    Akihiko.Urayama@uth.tmc.edu 

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Center for Translational Injury Research - Hemostatic/Vascular Dysregulation

    Postdoctoral Research Fellowship available in the lab of Dr. Jessica Cardenas

    A fully supported postdoc position is immediately available in the Department of Surgery, Center for Translational Injury Research, at the McGovern Medical School of the University of Texas Health Science Center at Houston.

    Research Summary:
    Dr. Cardenas’ lab is focused on hemostasis, thrombosis, and vascular biology, with a particular emphasis on hemostatic and vascular dysregulation in response to hemorrhagic shock. The specific goal of this position is to elucidate mechanisms by which the serine protease inhibitor antithrombin III (ATIII) regulates endothelial inflammatory responses and permeability following hemorrhagic shock, and how ATIII could potentially be used therapeutically to mitigate diffuse vascular dysfunction. Approaches in this lab are highly translational and utilize in vitro and in vivo models. In addition, the Cardenas lab collaborates closely with clinical colleagues to obtain human patient samples. We also collaborate with other departments, in particular, to study hemostatic and endothelial changes that affect hemorrhagic lesion expansion following traumatic brain injury. The fellow would have freedom to steer their project independently and develop new projects both within the lab and in collaboration with other labs/departments. The fellow will also receive mentorship from the PI and other senior members of the department and assistance with career development.

    Requirements:
    Applicants must have a Ph.D., M.D./Ph.D., or equivalent with a strong background in hemostasis, thrombosis, and/or vascular biology. The ideal candidate would be highly motivated, able to design and execute experiments, and willing to work both independently and in a team environment.

    To apply, please submit your CV, a letter of interest, and the names and contact information of three references to Jessica.C.Cardenas@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Center for Translational Injury Research - Trauma Research Fellowship

    Fellowship/Post-Doc Information

    Fellowship: NIGMS T32 Trauma Research Fellowship
    Length: 2 Years
    Total number of positions: 4(1-3 available/year)
    Program Director: Charles S. Cox, Jr., MD

    The University of Texas Health Science Center at Houston (UTHealth) is currently seeking postdoctoral candidates for a National Institute of General Medical Sciences (NIGMS)-funded T32 research fellowship in the following research areas: traumatic brain injury, resuscitation (including hemorrhagic shock), and organ injury and/or dysfunction. These are two year fellowships devoted to clinical or translational research. UTHealth and its primary clinical site, Memorial Hermann Hospital, are located in the heart of the Texas Medical Center in Houston, the largest incorporated medical center in the world. UTHealth’s Trauma Research Training Program was created in 1988, and over the last 25 years, multidisciplinary faculty have successfully mentored residents and postdocs to become competitive, productive, and independent clinical researchers.

    Program Goals

    The goal of this comprehensive program is to provide mentorship as well as didactic and practical training in clinical and translational research, resulting in significant contributions to the care of traumatically-injured patients and future academic independence. Upon the completion of the fellowship, fellows will be able to 1) formulate focused research questions and develop appropriate protocols to answer those questions; 2) analyze the resulting data and draw appropriate conclusions from these data; 3)collaborate with other scientists in a multidisciplinary setting; and 4) organize both oral and written presentations of research results, defend conclusions, and translate them to the care of the traumatically-injured patient. Fellows will participate in didactic coursework, including courses in clinical trial design, scientific writing, epidemiology, biostatistics, ethics and career development and have the opportunity to complete a Master of Science in Clinical Research. T32 fellows will be directly advised by a primary faculty mentor at UTHealth.

    Other Requirements

    UTHealth provides equal employment opportunities, is committed to recruiting a talented and diverse workforce, and encourages applications from under-represented ethnic minorities and veterans. Applicants must have an MD or PhD and be a U.S. citizen or permanent resident.

    How to Apply

    Interested applicants should send a current CV, a one page statement of research interests, a half page statement of career goals and three letters of reference to erin.e.fox@uth.tmc.edu. Complete applications are due by May 1, 2021. Fellowship positions will start July 1, 2021.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Diagnostic and Interventional Imaging- MRI Techniques in Neuroimaging

    Postdoctoral Research Fellow Position in Neuroimaging

    An exciting postdoctoral research fellow position is available immediately in the magnetic resonance research group in the Department of Diagnostic and Interventional Imaging at The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School.

    We are looking for a highly motivated individual with expertise in machine learning applications in MRI. The candidate is expected to be actively involved in developing highly innovative deep learning-based quantitative MRI techniques in neuroimaging, and work closely with colleagues from different disciplines. 

    The MRI section at McGovern Medical School is an active research site which led numerous technical developments and translational research. The MRI section has a state-of-art facility including a 3T Philips Ingenia MRI and a 7T Bruker animal dedicated scanner. The lab has plenty of technical and computational resources including GPU workstations and access to the Texas advanced computing center (TACC).

    Qualifications:

    Applicants should have a PhD in electrical or biomedical engineering, medical physics, computer science, or a related field with strong written and verbal communication skills, be highly organized, and able to prioritize their own work with minimal supervision.

    Previous experience in biomedical image registration, restoration, and segmentation, MRI image reconstruction, motion correction, fast imaging, pulse sequence programming, machine learning, computer vision, and pattern recognition, and fluency in Python and Matlab are highly desirable.

    To apply:

    Please send a cover letter, CV, and the names and contact information of three references along with a 1-page statement of goals electronically to Dr. Refaat Gabr at: refaat.e.gabr@uth.tmc.edu.

    Benefits:

    Salary and benefits will be commensurate with NIH and UTHealth guidelines. UTHealth offers a comprehensive and competitive benefits package. For more information please refer to the UTHealth Office of Benefits website. https://www.uth.edu/benefits/benefits-summary.htm 

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Epidemiology, Human Genetics and Environmental Sciences - Genomic Medicine Bioinformatics Toolbox

    The Department of Epidemiology, Human Genetics and Environmental Sciences at the UTHealth School of Public Health is seeking an exceptional candidate for a postdoctoral fellowship position. A postdoctoral fellow will be recruited to work under the supervision of Dr. Boerwinkle and Dr. Coban Akdemir. This postdoctoral fellow will be trained in genetics and computational biology and will use their expertise to develop an in-house genomic medicine bioinformatics toolbox and analytical framework. Those will achieve enhanced detection and variant prioritization from next-generation sequencing data of individuals presented with a wide variety of Mendelian disease traits. The toolbox and analytical tools will not only advance Mendelian discovery opportunity to expand the repertoire of genotype-phenotype correlations underlying Mendelian disease traits but will support elucidation of more complex models of human disease. Resources available for pursuing such research will also include whole-genome sequencing and other omics datasets available from the Atherosclerosis Risk In Communities Study, Genome Sequencing Program (GSP), Trans-Omics for Precision Medicine (TOPMed) program, and other large-scale biobank studies such as the UK Biobank. This position will be involved in writing manuscripts for peer-reviewed publication, reports, and presentations to academic and community audiences. The candidate will gain experience in grantsmanship, as well as research design, planning, and execution.

    Candidates must have a Ph.D. or equivalent doctorate in genetics, bioinformatics, computational biology, molecular biology, epidemiology, computer science or related field. Previous experience in analyzing genetic and genomics data e.g. next-generation sequencing data (exome, genome or RNA-sequencing data) and programming/writing scripts e.g. R or Python is highly desirable.

    To Apply

    Questions about the position can be directed to Dr. Zeynep Coban-Akdemir at zeynep.h.cobanakdemir@uth.tmc.edu. To apply for this position, please email the following documents to Dr. Coban-Akdemir: 1) a letter of interest that describes research accomplishments and future research plans, 2) full curriculum vitae, and 3) names and contact information of 2-3 individuals who will provide letters of recommendation if asked.  Application review will begin immediately and continue until the position is filled. Starting date is flexible and negotiable.

    Primary duties and responsibilities
    • Data analysis (40%)
    • Manuscript preparation (40%)
    • Help with grant preparation (10%)
    • Communicating with collaborators and other organizational work related to research (10%)
    Certification/Skills
    • Excellent writing skills
    • Good verbal communication skills
    • Next-generating sequencing data analysis
    • Understanding of basic genetic concepts
    • Programming/writing scripts in R or Python 
    • Epidemiological/statistical approaches

    • Population-based cohort studies 
    Minimum Education 

    PhD 

    Physical Requirements 

    Exerts up to 20 pounds of force occasionally and/or up to 10 pounds frequently and/or a negligible amount constantly to move objects.

    Security Sensitive: This job class may contain positions that are security sensitive and thereby subject to the provisions of Texas Education Code § 51.215

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Epilepsy - Neuroscience - Genetics

    A postdoctoral fellowship position is available to conduct research on the genetic basis of epilepsy and epilepsy-associated malformations. The ideal candidate will be an MD, PhD or MD,PhD graduate with a strong background or interest in neuroscience, epilepsy and genetics. The project will involve a multidisciplinary approach combining histology, genomics (NGS), bioinformatics, laser capture microdissection, immunohistochemistry and functional assays to the study of human samples from patients with epilepsy. The postdoctoral fellow is expected to integrate information from multiple platforms to gain insights into the pathophysiology and genomic alterations behind various epilepsy-associated lesions. The candidate will work primarily with human tissue and or fluid samples.

    Experience with histology, molecular biology, electrophysiology and/or next generation sequencing techniques (e.g., bioinformatics, targeted NGS panels, RNA-Seq, WES) is desirable but not required. The candidate must be a self-starter, motivated, and enthusiastic scientist. It is anticipated that the individuals selected will take responsibility for designing and carrying out research projects, assembling results of research into manuscripts for publication, and participate in laboratory maintenance. Additionally, the individuals will participate in the preparation of grants for submission to funding agencies and in providing guidance and assistance to other student members of the laboratory.

    The postdoctoral researcher will work under the guidance of Nitin Tandon, MD (Neurosurgeon, Vice Chair, Department of Neurosurgery and Director of Epilepsy Surgery Program) and Leomar Y. Ballester, MD,PhD (Molecular Neuropathologist and Co-director of the Molecular Diagnostics Laboratory). To apply for this position, send your CV with names/contact info of 3 references to Nitin.Tandon@uth.tmc.edu and Leomar.y.ballester@uth.tmc.edu.

    Dr. Tandon Laboratory website:

    https://med.uth.edu/neurosurgery/tandon-lab/

    http://www.tandonlab.org

    Dr. Ballester Laboratory website:

    https://med.uth.edu/pathology/ballester-esquenazi-laboratory/

    Salary will be commensurate with relevant experience and based on the prevailing wage of postdoctoral research trainees set by the U.S. Department of Labor. Full-scale state employee benefits will be provided in general. Houston is a dynamic world-class city that is alive with energy and rich in culture, history, diversity, sports, music and cuisine. Located in Texas Medical Center that is the biggest medical center worldwide, UTHSC Houston is an excellent academic environment and provides plentiful opportunities for career development.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Institute of Molecular Medicine - Center for Cardiovascular Genetics

    Postdoctoral Research Fellow Position

    Description

    • A research post-doctoral position is available for an energetic individual with research experience.
    • The position is in molecular genetics, genomics and molecular biology of cardiovascular diseases.
    • The candidate must have the ability to work independently as well as collaboratively.

    Qualifications

    • The candidate will work on DNA damage in heart failure.
    • Applicants should have completed a PhD in molecular genetics, genomics, molecular biology or related field.
    • Interested candidates should send a cover letter, their CV, and the names and contact information of three references electronically to: Ali.J.Marian@uth.tmc.edu

    (No Phone Calls please).

    The University of Texas is an EO/AA employer. M/F/D/V. This is a security-sensitive position and thereby subject to Texas Education Code §51.215. A background check will be required for the final candidate.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Institute of Molecular Medicine - Center for Molecular Imaging

    Overview

    A CPRIT-funded position is immediately available for a postdoctoral researcher in the Center for Molecular Imaging. The project focuses on lymphatic delivery of cancer immunotherapies to tumor draining lymph nodes to provide robust anti-tumor immunity without causing immune related adverse events that currently limit effectiveness. A successful candidate would be deploying numerous techniques in orthotopic tumor models to track lymphatic delivery, evaluate tumor and immune cell response, and elucidate immune escape mechanisms. In addition, there are opportunities for a successful candidate to participate in clinical studies of lymphatic delivery systems.

    Qualification

    A PhD in molecular biology, genetics, cancer biology, immunology, or other relevant field. Experience in animal models of cancer, flow cytometry, and molecular biology techniques are necessary and a desire to learn new imaging approaches. The candidate should be highly motivated, able to work independently, and demonstrate excellent communication and writing skills.

    Application

    Qualified candidates are encouraged to contact Dr. Eva Sevick directly at Eva.Sevick@uth.tmc.edu. In the email, please attach your CV, and a cover letter briefly describing your accomplishments and research interests and how those are a good fit for the position. In addition, include contact information for 3 references. Please use subject title “Postdoc Application”.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Institute of Molecular Medicine - Role of variable gene expression in human disease/trait risk

    Human Genetics/Genomics Postdoctoral Fellow

    An open position for a postdoctoral fellow in human molecular genetics/genomics field is available in the laboratory of Ashish Kapoor at the University of Texas Health Science Center at Houston (UTHealth).

    Overview

    The Kapoor lab focuses on understanding the role of variable gene expression driven by noncoding cis-regulatory sequence variation in human disease/trait risk. Although, genome-wide association studies (GWAS) have beyond doubt established a major role for variable gene expression as the basis for trait variation and disease risk, the underlying molecular mechanisms remain largely unknown. We utilize a wide array of genetic, biochemical, cellular, functional genomic, epigenomic and computational approaches to identify the molecular components and the structure of the regulatory apparatus underlying gene expression variation in humans. For more information please visit: https://www.uth.edu/imm/faculty/profile?id=19e3224f-26cc-4a97-8735-27a359e81c9c

    Application requirements

    We are seeking a talented and highly motivated individual with a Ph.D. in human genetics, genomics, or other relevant field to join the lab. The candidate must demonstrate scientific productivity, rigor and creativity with a strong publication record in peer-reviewed scientific journals. The candidate must demonstrate initiative and the capacity to conduct independent research. Excellent communication and organizational skills are required. The successful candidate will be leading projects on functional characterization of GWAS signals to understand the molecular basis of observed genetic associations.

    Experiments involved in these projects are diverse and include, but not limited to, transient medium-to high throughput enhancer reporter assays in cell lines and zebrafish embryos, identification of enhancer-TF interactions, target gene identification using gene expression associations, genome editing, clonal selection and gene targeting (gain- and loss-of function) in model systems including human induced-pluripotent stem cells derived cardiomyocytes (iPSC-CMs), in addition to transcriptomic and epigenomic profiling of cell types/tissues. Experience with animal (rodents and zebrafish) and cellular (iPSCs) models, and computational/statistical methods in genomics are preferred.

    Salary and benefits will follow National Institutes of Health and UTHealth guidelines. UTHealth offers limited housing opportunities for postdoctoral fellows and a large number of benefits. The Kapoor lab is located in the Center for Human Genetics at the Institute of Molecular Medicine, McGovern Medical School, UTHealth. UTHealth is one of the several institutions located at the world-renowned Texas Medical Center. The vast resources within UTHealth and other institutions at the Texas Medical Center make it an ideal place to facilitate the success of projects and provide avenues for collaborations with other laboratories.

    How to Apply

    Applicants should submit their CV, along with a letter outlining their interests and contact information of three references to ashish.kapoor@uth.tmc.edu with “Human Genetics/Genomics Postdoc” in the subject line.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Institute of Molecular Medicine - Skeletal Muscle Metabolism and Vascularization

    Postdoctoral positions in skeletal muscle metabolism and vascularization

    NIH-funded post-doctoral positions are available to examine the transcriptional regulation of angiogenesis, mitochondrial metabolism and regeneration in skeletal muscle ischemia as it pertains to Peripheral Arterial Disease and Muscular Dystrophies. For this work, we will use molecular targeting in in vitro cellular systems (e.g. muscle, endothelial cells) and in in vivo murine skeletal muscle disease models (Diet-induced obesity, Hindlimb ischemia, Muscular dystrophy) to investigate orphan receptor signaling in ischemic diseases.

    Information on our research program, which encompasses transcriptional regulation in metabolism, angiogenesis and regeneration, can be obtained at: https://www.uth.edu/imm/faculty/profile?id=7db27eb9-5758-4584-877f-adaa60dbbecb

    This position requires:

    • A recent or graduating PhD candidate with peer-reviewed 1st author publications in vascular, mitochondrial and/or skeletal muscle biology.
    • Extensive experience and hands-on technical training in one or more areas including molecular and cell biology, skeletal muscle histo-morphology and physiology, ischemia/angiogenesis, and mitochondrial dynamics.
    • Multi-tasking, creativity, independence, methodical approach to experimental design, excellent written and oral communication skills, and good interpersonal skills, along with strong commitment to succeeding in a research-oriented career.

    Interested candidates meeting the above requirement should apply by email (Vihang.A.Narkar@uth.tmc.edu) to Vihang Narkar, Ph.D., Associate Professor, Hamman Foundation Distinguished Professorship in Cardiovascular Research, Brown Foundation Institute of Molecular Medicine, The University of Texas McGovern Medical School in Houston, TX, 77030. Please include a cover letter briefly describing research interest and future goals, detailed CV, and contact information for 3-4 referees.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Institute of Molecular Medicine- Texas Therapeutics Institute- Protease inhibitory monoclonal antibodies (mAbs)

    Postdoctoral Research Fellow Position

    Supported by NIGMS MIRA, DoD CDMRP, NIAID R21, and endowment funds, three postdoctoral researcher positions are available in Dr. Xin Ge’s Laboratory to study protease inhibitory monoclonal antibodies (mAbs) for therapeutics development (PNAS 2016,113:14970; PNAS 2019,116:16314). The successful candidates will utilize novel protein engineering approaches for the discovery, characterization, and optimization of mAbs specifically inhibiting proteases of medical importance for the treatments of indications such as cancer, obesity, snake envenomation, and diabetic neuropathy. For more information on Dr. Ge’s research, please visit:

    https://www.ncbi.nlm.nih.gov/sites/myncbi/xin.ge.1/bibliography/public/

    Located in the heart of the Texas Medical Center, the Brown Foundation Institute of Molecular Medicine is a translational research institute that focuses on studying and preventing diseases at the genetic, cellular and molecular levels. As one of eight research centers within the IMM, the Texas Therapeutics Institute particularly encourages drug discovery. The Ge Lab, newly relocated from UC Riverside in summer 2021, aims to develop enabling technologies for facile discovery and engineering of bio-pharmaceuticals, such as inhibitory and neutralizing antibodies and therapeutic enzymes, which are important but challenging for current technologies. The successful candidates will have extensive opportunities for multiple collaborations with scientists at UTHealth and worldwide working in diverse areas of biology and drug discovery.

    Qualifications

    Applicants should have recently received (or expect soon) a Ph.D. in biochemistry, molecular biology, biochemical engineering or related disciplines. Highly motivated candidates with strong background and experience in protein science and engineering are encouraged to apply. Good publication record and prior experience in protein engineering techniques (e.g. library construction, phage display, FACS) are highly desirable. Qualified individuals should possess the ability to design experiments, interpret and track results, and utilize this information to enable hypothesis generation. Good written and oral communication skills and the ability to work well in a collaborative environment are also required.

    To Apply

    Please send a single PDF file including a personal statement, a full CV, contact information of references to: Prof. Xin Ge at xin.ge@uth.tmc.edu. Applications will be reviewed as they are received. Positions will remain open until filled.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Integrative Biology & Pharmacology - Cyclic AMP Signaling

    Laboratory of Dr. Carmen Dessauer is looking for a creative Postdoctoral Fellow to join a dynamic, innovative research team within a highly interactive department. Positions focus on spatial and temporal aspects of cyclic AMP signaling as they relate to arrhythmias, cardiac hypertrophy and other aspects of heart disease. Funded projects center on identification and characterization of macromolecular complexes that regulate downstream signal transduction and physiological processes. We employ multiple approaches in our research including biochemical, molecular, as well as sophisticated
    imaging techniques using FRET, FLIM, calcium imaging, and state-of-the art superresolution microscopy. Newer projects apply proximity-dependent biotin
    identification (BioID) and bioinformatics to identify network interactomes within cardiomyocytes.

    Applicants with a Ph.D., M.D./Ph.D. or equivalent and a strong background in cell signaling, biochemistry, imaging, pharmacology, and/or cardiac animal models are encouraged to apply. The candidate must be able to work independently, design experimental protocols, analyze data, write up protocols and manuscripts, and take the lead in defining the direction of a given project. One should also have a good comprehension of the English language, the ability to work and collaborate with others, as well as a high motivation level. Positions are aimed to provide excellent mentorship, training, and opportunities in cardiomyocyte signaling and cardiovascular diseases.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Integrative Biology and Pharmacology - Cancer Cachexia

    A Postdoctoral Position to Study Cancer Cachexia

    A Postdoctoral Fellow position funded by NIH is available immediately in Dr. Yi-Ping Li’s lab in the Dept. of Integrative Biology and Pharmacology, at the University of Texas Health Science Center at Houston (UTHealth).  Prospective candidates will join a research team to study the molecular mechanism of cancer cachexia, a wasting syndrome characterized by progressive loss of muscle mass and function seen in half of all cancer patients, and a major cause of cancer-related death.  NIH has issued several Provocative Questions in recent years soliciting research to address this understudied disorder.  Utilizing cell and molecular biological approaches, Dr. Li’s team has made significant progress recently in uncovering the signaling mechanisms of cancer cachexia using cell culture and animal models (PMID: 21847090, PMID: 28928431, PMID: 30342032, and PMID: 30705122). The funded projects seek to extend the understanding of the molecular mechanisms of cancer cachexia that inflicts skeletal and cardiac muscles, as well as fat tissues, and to translate preclinical findings to clinical interventions of cancer cachexia. 

    Highly motivated individuals with recent Ph.D. and strong background in cell biology, molecular biology and muscle physiology are encouraged to apply.  Salary is based on NIH scale.  Interested individuals should send CV and cover letter to:

    Dr. Yi-Ping Li; 6431 Fannin, University of Texas McGovern Medical School, Houston, TX 77030

    or e-mail to yi-ping.li@uth.tmc.edu 

    For more information about the laboratory see https://med.uth.edu/ibp/faculty/yi-ping-li-phd/ 

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Integrative Biology and Pharmacology - Muscle Energy Metabolism

    Post-Doctoral Position in Muscle Energy Metabolism

    A postdoctoral fellow position is available in the newly established laboratory of Dr. Yang Liu in the Dept. of Integrative Biology and Pharmacology at the University of Texas Health Science Center at Houston (UTHealth). Utilizing cell and molecular biological approaches and animal models, the Liu lab aims to understand the regulation of energy metabolism in skeletal and cardiac muscle during physical exercise as well as other pathophysiological conditions. Dr. Liu recently received the American Heart Association (AHA) Career Development Award and the University of Texas System Rising STARs Award to facilitate and promote research. For more information about Dr. Liu’s research see https://orcid.org/0000-0002-4428-3562.

    Applicant Profile

    • Ph.D. in cell biology, molecular biology, biochemistry, physiology, or related discipline
    • Highly motivated and capable to conduct independent research
    • Strong communication and writing skills with a track record of research productivity
    • Experience with rodent animal models and tissue culture techniques highly desirable, but not required

    To Apply

    Email the following materials to yang.liu.2@uth.tmc.edu:

    • Cover letter with a brief statement of candidate’s research interest
    • CV or NIH biosketch
    • Names and contact info for three references

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Integrative Biology and Pharmacology- Lipid Signaling and Metabolism

    Postdoctoral Position in Cell Signaling

    A postdoctoral fellow position is available immediately in the Department of Integrative Biology and Pharmacology at the University of Texas Health Science Center at Houston. We are looking for a highly self-motivated individual with a recent PhD degree in biomedical sciences and solid experience in cell signaling, molecular cell biology, and biochemistry. Experience with animal handling and mouse genetics is preferred. The candidate will study lipid signaling and metabolism, and inter-organelle communication in cancer or vascular disease. We employ interdisciplinary approaches, including animal and cellular imaging, biochemistry and molecular biology, proteomics, lipidomics, metabolomics, and functional genomics.

    The successful applicant will be working in an active research department within the renowned Texas Medical Center (TMC) and gaining exposure to cutting-edge cell biology technologies. The city of Houston also offers comfortable lifestyle and ample career opportunities. Competitive salary/benefits will be offered based on qualification.

    To apply, please send a cover letter, a CV, and contact information for three referees to Dr. Guangwei Du (guangwei.du@uth.tmc.edu).

    The University of Texas is an Equal Opportunity/Affirmative Action Employer. M/F/D/V. This is a security sensitive position and thereby subject to Texas Education Code § 51.215. A background check will be required for the final candidate.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Integrative Biology and Pharmacology- Mechanosensing and Mechanotransduction in Cancer Cells

    Post-Doctoral Position to study mechanosensing and mechanotransduction in cancer cells

    A postdoctoral fellow position is available in Dr. Yong Zhou’s lab in the department of Integrative Biology and Pharmacology, at the University of Texas Health Science Center at Houston. We are interested in understanding critical roles of membrane biology and lipid metabolism in cancer. Our approach integrates quantitative super-resolution imaging, biophysical assays and molecular/cellular biology. We also work with an interdisciplinary team with expertise ranging from theoretical molecular dynamic simulations, molecular biology, drug discovery/screening and animal models.

    Postdoctoral trainees will have full access to a state-of-the-art imaging facility, a Nikon Center of Excellence, one of 19 in the country.  Trainees will work closely with the PI to develop their independent research plans and career development plans. We emphasize all-around development of our trainees for future career in either academia or industry. Our department and our medical school offer extensive postdoctoral training programs, including grant writing courses and postdoctoral training certificate program.

    Applicant profile:

    1. Hold a PhD in biochemistry, biophysics, bioengineering, molecular biology, cell biology, or related fields.
    2. Experience in cloning, molecular biology and tissue culture techniques.
    3. Experience in imaging methodologies.
    4. Strong communication and writing skills.
    5. Strong publication record.

    To apply: please email the following materials to yong.zhou@uth.tmc.edu
    1. A cover letter explaining your previous research experience and why you feel our lab is a good fit for you.
    2. A detailed C.V.
    3. Names of contact information of three references.

     

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Integrative Biology and Pharmacology-Neuronal Excitability & Bioenergetics/Cancer Cell Signaling

    Two postdoctoral positions are available in the Venkatachalam Lab (WWW.UTFLYLAB.COM)

    The Venkatachalam lab has fully-funded postdoctoral positions available for highly motivated candidates. Interested individuals should send a statement of prior research experience and future goals (2-page MAX), a current CV, and the names and contact information of 3 references to Kartik Venkatachalam (kartik.venkatachalam@uth.tmc.edu).

    1. RELATIONSHIP BETWEEN NEURONAL EXCITABILITY AND BIOENERGETICS
    This project involves the examination of how neurons cope with the bioenergetic burden of maintaining electrical excitability.

    The long-term goals of this project are - 

    1. To reveal fundamental insights into how neurons leverage the plasticity inherent in bioenergetic pathways to maintain functionality over the lifespan of organisms.
    2. To identify actionable strategies that restore bioenergetic homeostasis in neurons that exhibit pathological alterations in excitability as consequences of advanced age and/or upon the onset of neurodegenerative diseases.

    Investigators involved in this project can expect to - 

    1. Leverage the power of Drosophila and mouse genetics to answer fundamental and translationally-relevant biological questions.
    2. Utilize state-of-the-art technologies for studying neuronal bioenergetics including optical recordings in live neurons, Seahorse metabolic flux assays, and metabolite tracing.
    3. Apply multi-OMIC strategies to determine how age- and neurodegeneration-dependent changes in chromatin accessibility, gene expression, and cellular lipid profiles influence neuronal excitability and bioenergetics.

    2. ROLES FOR LYSOSOMES AND MITOCHONDRIA IN CANCER CELL SIGNALING
    This project involves the examination of how cancer cells co-opt endolysosomal biogenesis and mitochondrial function to compel unmitigated cell proliferation, a protumor immune signature, and cell survival. Please refer to these publications (Jung et al. EMBO Reports and Jung et al. bioRxiv) to get an idea of our progress so far.

    The long-term goals of this project are -

    1. To reveal fundamental insights into how cancer cells rewire transcriptional and metabolic programs involving endolysosomes and mitochondria in order to cope with the steep demands of unmitigated proliferation and cell survival
    2. To identify actionable strategies that disrupt lysosomal and mitochondrial function in cancer cells in order to attenuate cell proliferation, induce cell death, and modify the immune environment in order to increase the effectiveness of immunotherapy.

    Investigators involved in this project can expect to -

    1. Study the roles of endolysosomes and mitochondria in supporting cancer cell signaling.
    2. Utilize state-of-the-art technologies for studying neuronal bioenergetics including optical recordings in live neurons, Seahorse metabolic flux assays, and metabolite tracing.
    3. Apply multi-OMIC strategies to examine how cancer cells modify chromatin accessibility, gene expression, and cellular lipid profiles in order to facilitate the role of endolysosomes and mitochondria in tumorigenesis.

    Available facilities include -

    1. The Venkatachalam lab is located in the Texas Medical Center that is home to a range of relevant core facilities for multi-OMIC analyses, flow cytometry, and microscopy.
    2. The department has a cutting-edge microscopy core (UTHealth Center for Advance Microscopy) with access to electron microscopes; confocal microscopes with resonant and spectral detectors and additional platform for assessing fluorescence lifetime; confocal microscopes for TIRF and super-resolution imaging (STORM); a Nikon N-SIM super-resolution structured illumination microscope capable of imaging in 2D, 3D, and TIRF-SIM; a fluorescence imaging system for detecting small molecules in living cells; and an IVIS Lumina XR.

    Required qualifications for suitable candidates are -

    1. Ph.D. or equivalent in life sciences.
    2. Excellent written and oral communication skills.
    3. Demonstrable expertise in standard molecular biology techniques for working with nucleic acids (for instance, molecular cloning, DNA/RNA extraction, PCR/RT-PCR etc.) and proteins (for instance, Western blotting and immunofluorescence.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Microbiology & Molecular Genetics - RNA Biology and Biochemistry

    Postdoctoral Research Fellow Position

    A postdoctoral research position is available in the laboratory of Dr. Nicholas De Lay in the Department of Microbiology at the University of Texas Health Science Center in Houston to study the mechanisms by which small regulatory RNAs (sRNAs) act to post-transcriptionally regulate gene expression in the model gram-negative bacterium Escherichia coli. This position is supported by funding from National Institute of General Medical Sciences (R01GM121368). In bacteria, sRNAs have been shown to play a key role in controlling biofilm development, motility, stress responses, antibiotic resistance, and virulence in response to specific signals.

    The major areas of interest of the De Lay laboratory are: (1) to understand how polynucleotide phosphorylase, an enzyme highly conserved in bacteria and eukaryotes, impacts sRNA stability and function in E. coli, (2) to discover additional proteins involved in sRNA-mediated regulation of gene expression and elucidate their roles, and (3) to understand the role of sRNAs in regulating Streptococcus pneumoniae virulence. S. pneumoniae is an important human pathogen and is the leading cause of bacterial pneumonia and sepsis. For more information, please visit Dr. De Lay’s website: www.delaylab.org

    Qualifications

    Qualified applicants should have a strong background in molecular biology and microbiology, and applicants with experience with RNA biology and biochemistry are preferred. Fluency in written and spoken English is required.

    To Apply

    Please send a single pdf document containing a cover letter, description of research experience and interests, curriculum vitae, and contact information for three references to nicholas.r.delay@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Microbiology and Molecular Genetics - Candida-host Interactions

    Post-doctoral positions available to study Candida-host interactions.

    Post-doctoral positions are available in the laboratory of Dr. Michael Lorenz in the Department of Microbiology and Molecular Genetics at the University of Texas McGovern Medical School in Houston.  The Lorenz lab (https://med.uth.edu/mmg/labs/lorenz-lab/) has a long-standing interest in understanding the interactions of Candida species with the innate immune system.  We have identified a large number of previously uncharacterized genes as candidate mediators of this interaction.  We are generating a library of mutant strains for these genes to further validate them as potential virulence factors via in vitro and ex vivo screening in multiple host-relevant conditions.  The most promising candidates will then be further analyzed to determine their molecular functions, roles in host interactions, and contributions to virulence.  This approach has already identified several genes with novel roles in fungal virulence and it is anticipated that multiple independent projects will arise from an expanded analysis of this gene set.

    Qualifications:

    Interested applicants should have earned (or be close to earning) a Ph.D. and have a strong background in molecular biology and/or microbiology.  A track record of productive, high-quality science is required.  Candidates should have excellent written and oral communication skills.

    To apply:

    Please send a CV, statement of prior research experience, and contact information for three references as a single PDF file to Michael.Lorenz@uth.tmc.edu.

    Salary is commensurate with experience and will follow university guidelines. Review of applications will begin immediately and continue until the positions are filled.

    Equal Employment Opportunity Statement:

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Microbiology and Molecular Genetics - Fungal-bacteria-gut Interactions

    Postdoctoral Positions in Fungal Genetics and Gut Microbiota

    The laboratory of Dr. J. Christian Perez (Associate Professor in the Department of Microbiology and Molecular Genetics at McGovern Medical School) is looking for highly motivated Postdoctoral Fellows. The laboratory uses a combination of genomics, genetics, bioinformatics and molecular biology approaches to study the biology of the yeast Candida albicans, a eukaryotic member of the human gut microbiota. Current projects are aimed at examining the fungus interplay with cohabiting bacteria, particularly Bacteroides thetaiotaomicron, and the mammalian intestine.

    Two recent publications from our lab which illustrate our current interests:

    Eckstein MT, Moreno-Velásquez SD, Pérez JC (2020) Gut bacteria shape intestinal microhabitats occupied by the fungus Candida albicans. Curr Biol 30: 1-9.

    Moreno-Velásquez SD, Tint SH, del Olmo Toledo V, Torsin S, De S, Pérez JC (2020) The regulatory proteins Rtg1/3 govern sphingolipid homeostasis in the human associated yeast Candida albicans. Cell Reports 30: 620-629.

    The successful applicant must have a PhD (or be close to complete their degree) and a strong foundation in genetics, molecular biology, bioinformatics, microbiology or biochemistry. At least one first-author publication in a top specialty journal is expected. Experience handling laboratory mice is desirable although not required.

    Applications from suitably qualified people from all sections of the community regardless of race, gender or disability are welcome. Applications should include a letter (of no more than 500 words) describing research accomplishments and research interests, CV, publication list, and contact information of 2-3 academic references. Please send applications as a single PDF file to Dr. Pérez (Jose.C.Perez@uth.tmc.edu) by Dec 15, 2020. Salary will follow NIH recommended pay scale. Informal inquiries about the position are welcome.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Microbiology and Molecular Genetics - Gram-negative Bacteria Outer Membrane

    Postdoctoral research fellow position (NIH funded) is available in the lab of Dr. Anna Konovalova

    The lab is a part of the Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth). UTHealth is located at the Texas Medical Center, the largest biomedical center in the world, bringing together basic science, translational research and clinical care.

    Research Summary:

    The laboratory is focused on how Gram-negative bacteria build and maintain the integrity of their cell envelope, the hallmark of which is the outer membrane. The outer membrane is essential and serves a major factor of intrinsic antibiotic resistance. We aim to provide a deep functional understanding of the OM assembly and homeostasis pathways and their interconnectivity as the first step in the scientific roadmap to antibiotic discovery. We combine classic genetics, state-of-the-art biochemistry, and innovative -omics approaches. Our research interest lies in two major areas: i) Biogenesis of surface-exposed lipoproteins (SLPs). Our goal is to define the mechanism of lipoprotein targeting and export to the bacterial cell surface to enable the development of predictive computational models for lipoprotein localization and genomic identification of SLPs. ii) Envelope stress responses. We study envelope stress responses both on the molecular level to determine mechanistic aspects of the signal transduction and on the system level, to determine the global regulatory networks that ensure the fidelity of the envelope assembly under different growth conditions, including antibiotic challenges.

    Job Description:

    We seek applicants who are motivated, rigorous and creative. Applicants should have or will shortly earn a Ph.D. in microbiology, molecular biology or a related field. Extensive experience in conducting molecular biology, genetics and/or biochemistry experiments is required. Additionally, applicants should have strong written and oral communication skills and work well with others.

    Contact Dr. Konovalova directly at anna.konovalova@uth.tmc.edu. Please include your 1) CV, 2) a brief description of your research background and interests, and 3) the contact information of three referees.

    Learn more:

    Anna Konovalova, PhD | McGovern Medical School (uth.edu)
    Home | Konovalova Lab (wixsite.com)

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Microbiology and Molecular Genetics - Host Response of Infected Caenorhabditis elegans

    Postdoctoral Position in Host Response of Infected Caenorhabditis elegans

    A postdoctoral position is available in the laboratory of Dr. Danielle Garsin (https://med.uth.edu/mmg/faculty/danielle-a-garsin/) in the Department of Microbiology and Molecular Genetics at The University of Texas Health Science Center at Houston. The Garsin lab has long studied the molecular aspects of host response to bacterial infection using C. elegans as a model. One response is controlled by a NRF1/2 homolog called SKN-1. A screen has been carried out and new regulators of this response have been identified, including some that are pathogen specific. This project will involve the characterization of these new regulators and will require propagation and genetic manipulation of C. elegans, biochemical assays and western blotting, molecular biology and cloning, fluorescent microscopy, and transcriptomic analysis.

    Qualifications:

    Interested applicants should be highly motivated and have a Ph.D. degree with a strong background in molecular biology. Previous training in C. elegans biology is highly desirable. Prior publication in internationally recognized journals is required and candidates should be fluent in spoken and written English.

    To apply:

    Please send a cover letter indicating which project(s) are of most interest and a brief description of prior research experience, a curriculum vitae, and contact information for three references in a single pdf file to: Danielle.A.Garsin@uth.tmc.edu.

    Salary is commensurate with experience and will follow university guidelines. Review of applications will begin immediately and continue until the positions are filled.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Microbiology and Molecular Genetics – Schistosome Immune Evasion

    Postdoctoral Position in Schistosome Immune Evasion 

    A postdoctoral position is available in the laboratory of Dr. Jayhun Lee in the Department of Microbiology and Genetics at McGovern Medical School at UTHealth Houston. The Lee laboratory focuses on understanding the molecular basis of schistosome development and its role in immune evasion and host-parasite interaction. Schistosomes are parasitic flatworms that cause schistosomiasis, a major parasitic disease that affects over 200 million people globally. Currently, there is a single available treatment, Praziquantel, which is effective in killing mature schistosomes, but is less effective towards immature schistosomes and does not prevent re-infection. Moreover, no vaccines are available and drug-resistant strains have been reported. Therefore, developing new approaches to target these parasites is urgently needed. 

    The major areas of interest of the Lee laboratory are: (1) to define the immune evasion mechanism that schistosomes employ through their esophageal gland, an anterior digestive organ essential for parasite survival and immune cell lysis (Lee et al., PNAS (2020)), (2) to discover developmental regulators and their function in production and maintenance of various schistosome cell types/tissues and their role in host-parasite interaction (Diaz Soria and Lee et al., Nat Commun (2020)), and (3) to develop novel in vitro culture platforms that better recapitulate the host microenvironment that can be used to dissect mechanisms of how schistosomes navigate and thrive inside the mammalian host.

    We use Schistosoma mansoni as a model parasitic organism and employ molecular and functional genomic tools including (single cell) transcriptomics, in situ hybridization, RNA interference, and high-resolution microscopy. We use mouse as a mammalian host to introduce genetically perturbed parasites, to dissect the mechanisms of gene function in parasite development and host-parasite interaction. For more information, please visit Dr. Lee’s website: https://med.uth.edu/mmg/faculty/jayhun-lee-phd/.

    Qualifications: 

    Qualified applicants should have Ph.D. (currently or by December 2021) with experience in developmental biology, parasitology, immunology, genetics, biochemistry, or molecular biology. Experience working with rodents is preferred but not required. The applicant should be fluent in written and spoken English, have a strong history of scientific publication(s), have an excellent troubleshooting and organizational skills as well as oral communication and interpersonal skills.

    To Apply:

    Please send a single pdf document containing (1) a cover letter, (2) description of research experience and interests, (3) curriculum vitae, and (4) contact information for three references to jayhun.lee@uth.tmc.edu. Salary is commensurate with experience and will follow university guidelines. Review of applications will begin immediately and continue until the positions are filled.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Microbiology and Molecular Genetics- Fusobacterium-mediated coaggregation with oral microbiota

    Two Post-doctoral positions available to study oral bacterium Fusobacterium nucleatum.

    Two NIH-funded Post-doctoral positions are available in the laboratory of Dr. Chenggang Wu in the Department of Microbiology and Molecular Genetics at the University of Texas McGovern Medical School in Houston.  The Wu lab (https://med.uth.edu/mmg/labs/wu-lab/) has a strong interest in the mechanism underlying Fusobacterium-mediated coaggregation with oral microbiota within dental plaque and the interplay between fusobacterial nutrition and its pathogenesis in oral disease and colon cancer.

    Qualifications:

    Interested applicants should have earned (or be close to earning) a Ph.D and have a strong background in molecular biology and/or microbiology.

    To apply:

    Please send a CV, statement of prior research experience, and contact information for at least 1 reference as a single PDF file to Chenggang.wu@uth.tmc.edu.  

    Salary is commensurate with experience and will follow university guidelines. Review of applications will begin immediately and continue until the positions are filled.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurobiology & Anatomy - Learning and Memory

    Postdoctoral Position for Large-Scale Recording in a Small-Brain Model System

    Postdoctoral research position to examine loci of non-synaptic plasticity and synaptic plasticity in an established in vitro analogue of operant conditioning (OC) of feeding behavior in Aplysia (Baxter and Byrne, 2006). To date, published studies have examined only five of the ~100 neurons and none of the hundreds of synaptic connections that comprise the neural circuit. To address this shortcoming, large-scale voltage-sensitive dye (VSD) recordings (Neveu et al., 2017), in combination with intracellular recordings, will be used to identify OC-induced changes in activity and synaptic properties in a substantial proportion of the neurons in the circuit. In addition, these studies will examine the extent to which short- and long-term memory share common loci and plasticity mechanisms.

    We are located within the Texas Medical Center and its very rich and collaborative neuroscience community including Baylor College of Medicine, Rice University, M.D. Anderson Cancer Center and the University of Houston.

    Applications are encouraged from individuals with backgrounds in imaging and electrophysiological recording techniques and experience with MATLAB. Please submit a current résumé, cover letter and contact information for three references as a single file attachment to John.H.Byrne@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurobiology & Anatomy- Exocytosis, Neurotransmitter Release and Visual Information Processing in the Retina

    Postdoctoral Position in Synaptic Physiology

    The Heidelberger Lab is looking to recruit motivated, collaborative and friendly teammates who want to work on exciting projects in exocytosis, neurotransmitter release and visual information processing in the retina.

    Description

    A postdoctoral position is available in the laboratory of Dr. Ruth Heidelberger. The Heidelberger Lab, located within the University of Texas Health Science Center in Houston and the vibrant Texas Medical Center, studies mechanisms of exocytosis in the early visual pathway and in other secretory cells using a combination of biophysical, biochemical and molecular approaches. A current focus is to elucidate the roles of a SNARE protein that is essential for vision (Janecke et al., 2021, Human Genetics) and is modulated by synaptic activity (Campbell et al., 2020, Frontiers in Cellular Neuroscience) in membrane fusion, synaptic vesicle dynamics, short-term plasticity, and the transmission of visual information across the mammalian retina.

    Qualifications

    Applicants should have earned (or be close to earning) a Ph.D., M.D./Ph.D or equivalent degree. The ideal candidate will be a highly motivated individual with knowledge of neuroscience, membrane biophysics or a related discipline and prior experience in patch-clamp electrophysiology. Candidates should have excellent written and oral communication skills.

    To Apply

    Please send a single PDF file to Dr. Ruth Heidelberger at ruth.heidelberger@uth.tmc.edu that includes: (1) a cover letter with a statement of current study and future research interests and career goals, (2) curriculum vitae, and (3) a list of three references with contact details.

    Salary is commensurate with experience and will follow university guidelines. Review of applications will begin immediately and continue until the position is filled.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurology - Huntington’s Research

    Two NIH-funded postdoctoral fellow positions are available in the laboratory of Andrey Tsvetkov in the Department of Neurology, The University of Texas McGovern Medical School at Houston (UTHealth).

    The laboratory carries basic and translational research, investigating molecular mechanisms of aging and age-associated neurodegenerative disorders. UTHealth is a part of the Texas Medical Center (TMC), the largest medical center in the world, which includes several leading biomedical research institutions, including MD Anderson Cancer Center, Baylor College of Medicine, Rice University, and other institution recognized worldwide as for their advanced neuroscience programs.

    The Tsvetkov lab is a part of the BRAINS Research Laboratory, funded by over a dozen of R01 grants, with expertise on stroke, aging, inflammation, sex-associated differences in neurodegeneration, Alzheimer’s disease, and Huntington’s disease.

    https://med.uth.edu/neurology/specialty-programs/brains-research-laboratory/ 

    The first project focuses on molecular mechanisms of Huntington’s disease regulated by nuclear phospholipids using cultured primary neurons, mouse models, and novel imaging techniques.

    The second project focuses on the molecular mechanisms of autophagy in human neurons.

    Potential side projects include (1) regulation of neuronal chromatin structure by G-quadruplex DNA; (2) translational research in chemotherapy-associated brain damage.

    We are seeking recent graduates with a Ph.D. in neuroscience, cell biology, molecular biology, or other relevant fields. Preference will be given to US citizens, permanent residents, and individuals currently located in the US. To apply, please send a CV and a cover letter describing your previous work and career goals, a putative starting date, and the contact information for three references to andrey.s.tsvetkov@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurology - Neurodegenerative Diseases

    Postdoctoral positions available for modeling neurodegenerative diseases using induced pluripotent stem cells (iPSCs)

    A postdoctoral positions is available immediately in the laboratory of Dr. Claudio Soto (https://med.uth.edu/neurology/faculty/claudio-soto//) located in the McGovern Medical School at the University of Texas Health Science Center in Houston, TX. Salary and benefits will be in accordance with the NIH salary scale for the FY 2017 (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-131.html).

    Position Description

    We study the molecular basis of degenerative diseases associated with misfolding and accumulation of proteins, particularly focusing in Alzheimer’s, Parkinson's and prion-related disorders. We are interested in modeling these diseases in neurons and 3D cerebral organoids derived from patients’ own iPSCs. We are searching for motivated and ambitious postdoctoral fellow, who can work independently to extend our current research in this area. The candidate will have the opportunity to grow independently and get involved in other exciting projects, including developments of chimeric mouse models with human neurons, and glial cells; development of stem cell based therapies for degenerative disease and brain regeneration studies. Our lab has maintained funding to support an average of 25 members for the last 15 years. We strongly value creativity and courage to question existing knowledge. Collegiality and team spirit of the lab members provide an environment that promotes the sharing of ideas and expertise, which are values that we look for in a prospective postdoctoral candidate. Required qualifications: The ideal candidate should have a PhD degree in research directly related to stem cell technologies, including generation and characterization of iPSCs and differentiation into neuronal cells. Working experience with cerebral organoids is a plus, as well as experience in in vitro fertilization, blastocyst injection and production of chimeric mice.

    Application Requirement:

    1. An updated Curriculum Vitae, preferably in the current NIH Biosketch format.
    2. The names of 3 referees, who can attest to your scientific/intellectual achievements and your collegiality.

    Please submit applications to: Gloria Galvan at Gloria.Galvan@uth.tmc.edu

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurology- Parkinson's Disease

    Seeking a Postdoctoral Research Fellow

    We are seeking a motivated Ph.D. graduate to join The Mitchell Center for Alzheimer’s disease and Related Brain Disorders in the Department of Neurology at The University of Texas Health Science Center at Houston. Our research focuses on understanding the molecular basis of neurodegenerative diseases associated with misfolding and accumulation of proteins implicated in Alzheimer’s and Parkinson's diseases. The candidate will work on the characterization of alpha-synuclein strains derived from patients with Parkinson's disease and other synucleinopathies. The study will use various cellular (differentiated neurons and glial cells derived from iPSCs) and animal models of Parkinson’s disease.

    Required Qualifications:

    The ideal candidate with a PhD degree in basic science having work experience in differentiation and characterization of cells derived from iPSCs and animal models of Parkinson’s disease is highly encouraged.

    Major Duties:

    • Data collection, processing, and analysis.
    • Assists faculty researchers and other collaborators, or may act independently, in planning and designing research experiments.
    • Operates specialized scientific equipment
    • Engaged in fieldwork and writing of scientific publications and reports.
    • Presentation of project results to internal and external parties.
    • May be responsible for training staff, graduate assistants, or student employees

    To Apply

    Please send a current resume/curriculum vitae and the names and contact information of three references to:

    Mohammad Shahnawaz, PhD

    Assistant Professor

    Department of Neurology

    McGovern Medical School at UTHealth in Houston

    6431 Fannin Street, MSE R456

    Houston, Texas 77030

    E-mail: Mohammad.Shahnawaz@uth.tmc.edu

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neuroscience - Rafts and the Molecular Structure of Biological Membranes

    Postdoctoral Research Fellow

    A postdoctoral fellow position is available immediately in the laboratory of Dr. Neal Waxham (https://sites.google.com/uth.edu/waxham-lab/home) to investigate how the lipid composition of mammalian membranes, in particular neuronal membranes, controls their physical and structural properties.  We are particularly interested in how lipid composition controls the existence of ordered and disordered domains that lead to self-organization - physical properties underlying the "raft" hypothesis for membrane organization.  This project is centered on the use of cryo-electron microscopy as an exciting new tool (Heberle et al., PNAS, 2020) to quantify the characteristics of synthetic membranes of known composition at the sub-nanometer level.  Additionally, we compare unique signatures identified in known samples, to those imaged in native membranes of cellular organelles and intact neurons (Fischer et al., PloS Biology, 2018).  This position is funded through a collaborative NIH grant with the labs of Dr. Fred Heberle at the Univ. of Tenn. and Dr. Ilya Levental at the Univ. of VA.  The Waxham lab is fully equipped to prepare and image cryo-preserved samples using single-particle and tomographic approaches.  The cryo-microscopes are a shared resource run through the Structural Biology Center at McGovern Medical School.  The Waxham lab has broader interests in mechanisms governing neuronal communication and how those mechanisms are engaged during learning and memory and this novel work would integrate into on-going fluorescence and computational studies governing synaptic function.  Understanding how the lipid composition controls signaling at the neuronal membrane (Tulodziecka et al., Mol. Biol.Cell, 2016) is a necessary step towards achieving this long-term goal.

    Minimum Requirements

    The minimum degree for this position is a Ph.D. and experience in the biophysical/biochemical properties of membranes and/or cryo-electron microscopy techniques would be an advantage. 

    Description of Qualified Candidates

    Candidates should have a foundation in quantitative sciences, ideally in the fields of biochemistry, biophysics, structural biology or related disciplines.  Experience in computational sciences/programming and image processing would also be desirable.

    To Apply

    Please send your CV, a one page statement of interest with a few sentences on how this project and laboratory meet your career goals, and contact information for 3 people who can provide letters of reference.  This material should be sent to Dr. Waxham at m.n.waxham@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurosurgery - Cancer Biology Research

    Postdoctoral Fellow/Associate

    This is an exciting opportunity in Dr. Kaur’s laboratory to explore cancer biology and drug development. This is a molecular biology translational research lab working on cancer drug development. The laboratory is well funded through federal and industry contracts. The goal of the overall research is to develop novel agents that exploit cancer and tumor microenvironment sensitivities to create unique agents that can treat cancer.

    The candidate will work with a team of clinicians, bioinformatics and scientists to develop and test novel therapies for cancer. The candidate will be part of a multi-disciplinary team, and will have access to cutting edge state of the art technology. The laboratory is in the heart of the Texas Medical center, the largest medical center in the world.

    Past trainees from the Kaur laboratory are working as independent investigators at leading institutions like NIH, Ohio State University, University of Texas Health science Center, Hamamatsu University, Harvard Medical school, Japan etc. Several of our past trainees are also employed in pharmaceutical industries like Amgen, Invivo, etc.

    Seeking highly qualified person who have a passion for science. First author manuscripts from graduate thesis work are preferred. Applicants should have a Ph.D. in molecular/cellular biology, immunology, or a related discipline with strong organizational, oral and written communication skills. Previous experience with in vitro and in vivo models, and some basic knowledge of bioinformatics, is highly desirable though not required. Salary and benefits will be commensurate with the NIH and the UTHealth guidelines.

    To apply please send email with CV to: balveen.kaur@uth.tmc.edu

    Position Summary:

    Plans, supervises, and directs research, investigation, or other technical operations in a highly collaborative environment. Provides technical expertise to facilitate the design, implementation, and analysis of procedures, techniques, and results, which enables investigators to conduct research projects.

    1. Create and conduct experiments.
    2. Process and analyze results and data.
    3. Write manuscripts, and fellowship grants
    4. Communicate results to the scientific community via published papers, and at National meetings. Present ongoing work and findings to colleagues at academic conferences, and summaries the nature of the research, methodology and results.
    5. Work in multidisciplinary teams, in different faculties or schools in academia.
    6. Carry out peer reviews of written publications and presentations to validate theories and inform research.
    7. Keep up to date with the work of other scientists, participate in journal clubs.

    Selected Recent Publications from Kaur Laboratory:

    1. Xu B, Ma R, Russell L, Yoo JY, Han J, Cui H, Yi P, Zhang J, Nakashima H, Dai H, Chiocca EA, Kaur B, Caligiuri M, Yu J. An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy. Nature Biotechnology (2018) doi: 10.1038/nbt.4302. [Epub ahead of print].
    2. Russell L, Swanner J, Jaime-Ramirez CA, Wang Y, Sprague A, Banasavadi-Siddegowda Y, Yoo JY, Sizemore GM, Kladney R, Zhang J, Lehman NL, Ostrowski M, Hong B, Caligiuri M, Yu J, Kaur B. PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance. Nature Communications. (2018). 9(1):5006. doi: 10.1038/s41467-018-07344-1.Corresponding Author.
    3. Kim Y, Yoo JY, Lee TJ, Liu J, Yu J, Caligiuri M, Kaur B*, Friedman A*. Complex Role of NK cells in regulation of OV-Bortezomib therapy. Proc. Natl. Acad Sci. USA. (2018,). 15(19):4927-4932. * Co-Corresponding Author
    4. Banasavadi-Siddegowda YK, Welker AM, An M, Yang X, Zhou W, Shi G, Imitola J, Li C, Hsu S, Wang J, Phelps M, Zhang J, Beattie CE, Baiocchi R, Kaur B. PRMT5 as a drug gable target for glioblastoma therapy. (2018) Neuro-Oncology. 20(6): 753-763. Corresponding Author
    1. Hong B, Muilli K, Bolyard C, Russell L, Lee TJ, Banasavadi-Siddegowda Y, Yoo JY, Yan Y, Ballester L, Bockhorst K, Kaur B. Suppression of HMGB1 released in the glioblastoma tumor microenvironment reduces tumoral edema. Molecular Therapy Oncolytics (2018). 2:93-102.
    2. Yoo JY, Swanner J, Otani Y, Nair M, Park F, Banasavadi-Siddegowda Y, Liu J, Jaime-Ramirez CA, Hong B, Geng F, Guo D, Bystry D, Phelps M, Quadri H, Lee TJ, Kaur B. Oncolytic HSV therapy increases trametinib access to brain tumors and sensitizes them in vivo. Neuro-Oncology (2019)
    3. Bangxing Hong, Valerie Chapa, Uksha Saini, Puneet Modgil, David E. Cohn, Anil K. Sood, Yanquing Yan, Selvendiran Karuppaiyah, Guangsheng Pei, Zhongming Zhao, Ji Young Yoo, and Balveen Kaur, oHSV alters vesicular trafficking to induce Cisplatin sensitivity and anti-tumor immunity, Clinical Cancer Research, 2020, Provisionally Accepted
    4. Otani Y, Yoo JY, Chao S, Liu J, Jaime-Ramirez AC, Lee TJ, Hurwitz B, Yan Y, Dai H, Glorioso JC, Caligiuri MA, Yu J, and Kaur B. Oncolytic HSV infected glioma cells activate NOTCH in adjacent tumor cells sensitizing tumors to gamma secretase inhibition. Clinical Cancer Research (2020) May 15;26(10):2381-2392.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurosurgery - Cerebrovascular Biology

    A postdoctoral position is available immediately to study the development and maintenance of blood-brain barrier (BBB) in the CNS endothelial cells in the Department of Neurosurgery, University of Texas Health Science Center, Houston, Texas.

    The blood-brain barrier protects the brain from circulating toxins and foreign bodies. Compromise in BBB integrity is reported in several neurological diseases including stroke, traumatic brain injury, subarachnoid hemorrhage, and neurodegenerative diseases. We have been using various epigenetic, molecular, transgenic and gene targeting approaches to study the BBB gene regulation in CNS endothelial cells and target this regulatory mechanism to restore BBB.

    NIH scale salary and excellent work environment are offered. Self-motivated individuals with a Ph.D. degree in any area of biomedical sciences and especially those who are skilled in epigenetic, molecular biology and animal experience are encouraged to apply. Please send CV and names of three references to Peeyush.K.ThankamaniPandit@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurosurgery - Intracranial Aneurysm Research

    Postdoctoral Fellow Position in Intracranial Aneurysm Research

    A postdoctoral fellow positions is available in the Department of Neurosurgery at the University of Texas Health Science Center at Houston, to identify and study the genes that play causative roles in intracranial aneurysms with an emphasis on analyses in mice. The rupture of an intracranial aneurysm causes subarachnoid hemorrhage, a type of stroke that is responsible for >25% of years lost among all stroke victims under the age of 65.

    Recently, we discovered the first gene whose mutation is implicated in intracranial aneurysm (both familial and sporadic cases) and have confirmed its contribution to pathogenesis using a mouse loss-of-function model. The major research interests in the lab are: (2) to elucidate the functions of identified aneurysm gene(s) using cell based and animal models; (2) to characterize additional novel aneurysm genes using both candidate and genome-wide techniques; (3) to translate these discoveries into potential new therapies. Projects rely upon in vitro methodologies, cell culture studies, high-throughput genomics, and in vivo functional analyses in genetically engineered mouse models and zebrafish.

    Houston is the fourth largest city in the United States and is characterized by its low cost of living in comparison to other major metropolitan areas. As the largest medical center in the world, the TMC has a robust scientific community that includes multiple institutions including Baylor College of Medicine, Methodist Research Institute, Texas A&M IBT, and the University of Texas MD Anderson Cancer Center with whom we share a joint Graduate School of Biomedical Sciences (GSBS).

    Qualifications

    Interested applicants should be highly motivated and have a Ph.D. degree with a strong background in molecular biology and preferably mouse genetics and cerebrovascular research. Prior publication in internationally recognized journals is required and candidates should possess excellent oral and written communication skills.

    To Apply

    Please send a cover letter, a brief description of research experience and interests, a curriculum vitae and contact information for three references in a single pdf file to: UTHPostdocNeurosurgery@gmail.com

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurosurgery - Mechanisms Controlling the Formation, Maintenance, and Repair of the Blood-brain Barrier

    Postdoctoral Fellow, UTHealth Houston

    The Pandit Lab in the Department of Neurosurgery at the University of Texas Health Science Center at Houston seeks a Postdoctoral Fellow to participate in NIH/NINDS-funded studies as part of an ongoing lab effort to uncover the mechanisms that control the formation, maintenance, and repair of the blood-brain barrier, incorporating genetic, biochemical, neuroanatomical, and behavioral approaches and transgenic mouse models.

    The Postdoctoral Fellow will take the lead in conducting and coordinating a wide array of experiments and procedures, for example, ischemic stroke mouse model, ChIP-qPCR, isolation of endothelial cells from the brain, brain slice preparations coupled with, embryonic injections and neuropharmacology in the developing and mature brain, immunohistochemistry, Western blot analysis, and behavioral testing.

    The Pandit Lab encourages each trainee to explore and develop his/her own research directions. UTHealth Houston offers outstanding collaborative research and learning environment. The PI is committed to mentoring postdoctoral fellows to achieve their professional and career aspirations.

    Minimum requirements include (1) Ph.D. in neuroscience or related discipline, (2) working expertise in at least two of the above-mentioned experimental approaches, (3) strong motivation to learning new experimental approaches, (4) ability to function independently and as part of a research team, and (5) commitment toward achieving scientific and career goals. A start date in 2021 is preferred.

    Please send a cover letter describing research experience, interests, and aspirations, CV, and contact information of 3 referees to Dr. Peeyush Pandit at Peeyush.k.thankamanipandit@uth.tmc.edu

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

     

  • Neurosurgery - Nanomedicine/Oncology

    Postdoctoral Fellow

    Position Summary:

    A postdoctoral position is available immediately to study nanomedicine/oncology field in the Department of Neurosurgery, McGovern Medical School, the University of Texas Health Science Center at Houston. 

    The laboratory focuses on basic and translational studies on a role of deregulated microRNAs in tumorigenesis and developing a strategy to treat brain tumors using cutting edge RNA-based nanomedicine. Brain tumors are the second-leading cause of cancer-related death with limited options of treatment. The same concept is also applied to other types of cancer to examine the role of oncogenic or tumor suppressive microRNAs in various type of human cancers, such as liver cancer, colorectal cancer and lung cancer, as well as perioperative acute respiratory disease syndrome, which has been related to the recent COVID-19 cases. The research will make a visible impact on the development of reliable strategy for cancer therapy by reprograming deregulated microRNAs in cancer patients by designing novel and innovative RNA nanoparticles that can be applied to future human clinical trials.

    Any candidates with Ph.D. and previous experience of molecular biology and mouse models are highly recommended to apply, and send CV and names of three references to Tae.Jin.Lee@uth.tmc.edu. NIH scale salary and excellent work environment are offered.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurosurgery - RNA/Breast Cancer Research

    Postdoctoral position in RNA Biology/Breast Cancer Research

    A postdoctoral fellow position is available in the lab of Dr. John Hagan at the University of Texas Health Science Center at Houston (UTHealth) located within the Texas Medical Center (TMC). Our research is focused on elucidating the functions of a newly discovered form of posttranscriptional gene regulation mediated by 3’ RNA uridylation that plays critical roles in mammalian development and disease, including cancer. Uridylation is a form of epitranscriptomics where the non-templated addition of uridine(s) controls directly mRNA stability and microRNA biogenesis.

    The major interests in the lab are: (1) to elucidate the functions of the TUTases including Zcchc11 that regulates the tumor suppressor let-7 microRNA family via the oncogene and reprogramming factor LIN28A; (2) to determine how 3’ RNA uridylation drives poor prognosis in breast cancer and gliomas, independent of the LIN28/let-7 pathway; (3) to translate these discoveries into potential new therapies. Projects rely upon biochemistry, cell culture studies, high-throughput genomics, and in vivo functional analyses in genetically engineered mouse models with an emphasis on breast cancer models.

    Houston is the fourth largest city in the United States and is characterized by its low cost of living in comparison to other major metropolitan areas. As the largest medical center in the world, the TMC has a robust scientific community that includes multiple institutions including Baylor College of Medicine, Methodist Research Institute, Texas A&M IBT, and the University of Texas MD Anderson Cancer Center with whom we share a joint Graduate School of Biomedical Sciences (GSBS).

    Qualifications

    Interested applicants should be highly motivated and have a Ph.D. degree with a strong background in molecular biology and mouse studies. Prior publication in internationally recognized journals is required and candidates should be fluent in spoken and written English.

    To Apply

    Please send a cover letter that includes a brief description of research experience and interests, a curriculum vitae, and contact information for three references in a single pdf file to: UTHPostdocNeurosurgery@gmail.com.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurosurgery - Spinal Cord Injury/Pain/Biomarker Discovery

    Postdoctoral Research Fellow Position in Spinal Cord Injury/Pain/Biomarker Discovery

    A post-doctoral fellow position is available to study biomarkers prognostic of chronic neuropathic pain after spinal cord injury.  The position is in the Vivian L. Smith Department of Neurosurgery, McGovern Medical School at The University of Texas Health Science Center at Houston.

    The laboratory focuses on biomarker discovery.  This is a bi-directional translational laboratory where discoveries identified in human samples are later tested in animal models to determine causality and/or test potential therapeutics.  Therapeutics effective in animal models will then be tested in human subjects.  The fellow filling this position will work with human subjects, rodent models and perform laboratory studies. 

    Minimum Requirements

    Applicants must have a Ph.D. in a relevant discipline (e.g., neuroscience, immunology, molecular biology). Must be proficient in scientific writing and working with large datasets. Certifications for the Protection of Human Research Subjects, UTHealth’s Center for Laboratory Medicine Animal Care Training Courses, and enrollment in the UTHealth occupational health program will be required within the first weeks of employment.

    Description of Qualified Candidates

    • The applicant must have a record of research productivity through publications and presentations related to pain, inflammation, trauma, central nervous system, immunology or biomarker discovery.
    • Experience and/or interest in working with human subjects and rodent models.
    • Competitive applicants should also possess skills in statistical methods and managing large data sets.
    • Ability to work both independently and as a collaborative team member.
    • Excellent interpersonal, verbal, and written communication.
    • Strong organizational skills

    Required Application Materials

    1. A cover letter describing professional interests and goals
    2. CV
    3. Citation or sample of scholarly writing.
    4. Names, titles and contact information of 3 professional references.

    SECURITY SENSITIVE: 

    This position includes access to protected information and requires strict compliance with HIPAA security standards and other local and federal regulations.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Neurosurgery- BRAIN Program

    Postdoctoral Fellowship Position at BRAINS Research Group

    An exciting postdoctoral position is available immediately to study how the gut microbiome affects inflammation in aging and post-stroke recovery in The BRAINS Research Group at the McGovern Medical School part of University of Texas Houston. The candidate will benefit from a multi-disciplinary training experience in a highly collaborative environment. The BRAINS’ Research Group is a dedicated network of NIH & AHA funded scientists conducting basic, translational, and clinical studies to understand how sex differences, aging, and inflammation affect post-stroke recovery identifying targets for possible treatments. The successful candidate will have the opportunity to gain in vivo experience in stroke models using techniques, such as, ELISA/multiplex, flow cytometry, Quantitative RT-PCR, immunohistochemistry, behavioral testing, among others.

    Applicants should have a Ph.D. degree in molecular/cell biology, microbiology, immunology, gastroenterology or a related discipline with strong organizational, oral and written communication skills. Previous experience with in vitro and in vivo models, and a strong background in immunology, microbiology, bioinformatics, and RNAseq analysis if highly desirable. Salary and benefits will be commensurate with the NIH and the UTHealth guidelines.

    To apply for this position, send your CV with names/contact info of 3 references to Diego Morales-Scheihing Ph.D.,MBA. Sr. Program Manager (Diego.Morales@uth.tmc.edu).

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Pediatric Neurosurgery

    POSTDOCTORAL RESEARCH FELLOW POSITION SUMMARY:

    Manages the day-to-day activities for pediatric neurosurgical research projects of considerable scope and complexity. Plans, conducts, and directs a wide variety of experiments.

    POSITION KEY ACCOUNTABILITIES:

    1. Collects, evaluates, interprets, and documents research pediatric neurological MRI, magnetoencephalography and optical imaging data to accomplish the objectives of a variety of research projects.
    2. Uses Command-line Linux, Python, R, MATLAB, Brainstorm and common neuroimaging programs such as FSL, AFNI and FreeSurfer to analyze neuroimaging data.
    3. Influences project direction and outcomes by identifying opportunities to enhance, terminate, or re-direct research activities.
    4. Helps in the recruiting and documentation of study participants.
    5. Evaluates and interprets data and provides results to investigators to support publication
    6. Maintains quality control checks and a safe environment in compliance with all governmental and University policies, rules, regulation and codes.
    7. Assists in the preparation and writing of research reports, manuscripts, papers and grant proposals for presentation and publication.
    8. Attends laboratory meetings of affiliated co-investigators.
    9. Collects, evaluates, interprets, and documents research data to accomplish the objectives of a wide variety of scientific experiments and research projects.
    1. Influences project direction and outcomes by identifying opportunities to enhance, terminate, or redirect research activities.
    2. May recruit study participants or field interviewers.
    3. Evaluates and interprets data and provides results to investigators to support publication.
    4. Maintains quality control checks and a safe environment in compliance with all governmental and University policies, rules, regulation and codes.
    5. Assists in the preparation and writing of research reports, manuscripts, papers and grant proposals for presentation and publication.
    6. Provides direction and training to lab personnel to ensure efficient, timely and high quality results in compliance with all protocols, guidelines, regulations, etc.
    7. Performs other duties as assigned.

    CERTIFICATIONS/SKILLS:

    • Required to work on UT Health TMC Campus in lab environment
    • Certification for Protection of Human Research Subject may be required or must be completed within 5 days of employment.
    • MATLAB coding experience
    • UNIX experience
    • Familiarity with neuroimaging software such as FSL, AFNI and FreeSurfer
    • Python and R coding experience preferred
    • Machine learning experience preferred

    MINIMUM EDUCATION:

    Ph.D. in research related field, PhD in neuroimaging preferred.

    MINIMUM EXPERIENCE:

    Three years related research or clinical or other experience.

    TO APPLY: 

    Contact: Manish Shah, M.D
    Email Manish.N.Shah@uth.tmc.edu

    or send letter with CV:

    Samantha Fox-Monroe Executive Assistant
    Department of Pediatric Surgery, McGovern Medical School
    6431 Fannin Street, MSB 
    Houston, TX 77030

    PHYSICAL REQUIREMENTS:

    Exerts up to 20 pounds of force occasionally and/or up to 10 pounds frequently and/or a negligible amount constantly to move mobile computer workstation.

    SECURITY SENSITIVE: 

    This job class may contain positions that are security sensitive and thereby subject to the provisions of Texas Education Code § 51.215

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Pediatric Surgery - Pediatric and Neonatal brain injury

    The Department of Pediatric Surgery is seeking a postdoctoral fellow to participate in studies of neuroinflammation, white matter injury, pharmacologic therapy and stem cell biology in the context of pediatric and neonatal brain injury. Current NIH-funded projects are focused on the consequences of neonatal intraventricular hemorrhage and therapeutic strategies to reduce inflammation and brain injury. Techniques employed include stereotactic injections, histology, biochemistry, neurobehavior assessment and primary CNS cell culture.

    The fellow will have their own dedicated office space within the new SCRB3 building in the Texas Medical Center. Lab benches, surgical suites, microscopy and cell culture facilities are located on the same floor as the office space and are shared with members of the Pediatric Program in Regenerative Medicine with whom the postdoctoral fellow will collaborate.

    The fellow is expected to develop their own independent projects and collaborate on group projects within the program. There will be access to many collaborators within the departments of Pediatric Surgery, Neurology, and Neurosurgery at the University of Texas and MD Anderson Cancer Center. Applicants should have experience with small animal surgery, molecular biology and cell culture. A PhD in Neuroscience or a related field is required.

    Postdoctoral fellows at UTH receive benefits such as retirement programs as well as specific resources for postdoctoral fellows such as workshops in grant writing and manuscript production. Relocation funding is available. Houston is the fourth largest city in the United States and is characterized by its low cost of living in comparison to other major metropolitan areas. It has a diverse culture, vibrant food and music scenes, and two international airports.

    As the largest medical center in the world, the TMC has a robust scientific community that includes multiple institutions including Baylor College of Medicine, Methodist Research Institute, Texas A&M IBT, and the University of Texas MD Anderson Cancer Center with whom we share a joint Graduate School of Biomedical Sciences (GSBS).

    To Apply: 

    Please send a cover letter indicating current study and future research interests, curriculum vitae/resume and the names and email addresses of three references to:

    Brandon.A.Miller@uth.tmc.edu 

    Diane.Harnden@uth.tmc.edu

    Check us out:  https://med.uth.edu/pediatricsurgery/ 

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Pediatrics - Children's Learning Institute

    IES Postdoctoral Research Fellow Position at UTHealth

    The Children’s Learning Institute (CLI) within the UTHealth Department of Pediatrics seeks a candidate who demonstrates interest in postdoctoral research training focused on developmental and academic outcomes of preschool and early elementary children with or at risk for disabilities. Candidates need interest and background in on or both of the offered training topics: (1) Early Interventions & Assessments, and/or (2) Scalable Professional Development (PD) for Educators of Young Children. Our training framework is focused on helping fellows understand the benefits of Research-Practice Partnerships (RPPs) and develop skills to become valuable partners with practitioners through all stages of their research career. We believe future generations of education and child development researchers must be directly trained to value rigorous and relevant research within RPPs to produce scholarship that is relevant, scalable and addresses the most pressing needs of young children with or at risk for learning disabilities.

    This Postdoctoral Research experience is a competitive training program funded by the Institute of Education Sciences (IES) National Center for Special Education Research (NCER) that will support a total of four fellows for two years each. Fellows will work with a primary mentor and a secondary mentor as well as team of educators, clinicians, and experts at CLI on aspects of education research design, partnerships, data collection, statistical analyses, dissemination through scholarly publications and presentations, and the development of grant applications. Planned training will occur within several strands that include required and optional activities. For example, one training strand will ensure fellows understand how to conduct rigorous research that meets the IES Standards for Excellence in Education Research and What Works Clearinghouse standards. Another training strand will ensure fellows enhance their professional skills by working within multidisciplinary teams at CLI as well as other researchers and educators focused on improving outcomes of young children with or at risk for disabilities.

    We expect Postdoctoral Fellows will produce scholarly publications, participate in preparation of research grants, and conduct their own original research project within an active project. Much of Fellow’s training will occur through the leadership roles and management of aspects of an active grant at CLI to include the Fellow’s original research. Therefore, applicants’ cover letter should indicate how their interests align with one or more of the five active projects detailed below. The Fellow will be matched with one of three primary mentors at CLI - Susan Landry, Ph.D., Tricia Zucker, Ph.D., April Crawford, Ph.D. Fellows will also work with several secondary mentors, including Yoonkyung Oh, Ph.D., Michael Assel, Ph.D., and Cheryl Varghese, Ph.D.

    This position is funded by the Pathways to the Education Science Research Training program, which was established by IES to develop a pipeline of talented education researchers who bring fresh ideas, approaches, and perspectives to addressing the issues and challenges faced by the nation's diverse students and schools. Should you wish to obtain more information regarding The Pathways Training Program and its mission, please refer to it’s website at https://ies.ed.gov/ncer/projects/program.asp?ProgID=95 for details.

    The position is for two years and the salary will be $60,000 annually with benefits. Candidates will also receive a small stipend to cover research costs.

    Minimum Requirements

    Applicants must have a Ph.D. or Ed.D. in a relevant discipline (e.g., education, public policy, psychology, developmental psychology, educational psychology, curriculum instruction, and special education, economics, sociology, political science, public health or related fields).

    Description of Qualified Candidates

    • The applicant must have a record of research productivity through publications and presentations related to child development, education, or school-related public policy.
    • Competitive applicants should also possess skills in applied statistical methods; applicants with advanced statistical skills should explain their current knowledge.
    • Ability to work both independently and as a collaborative team member.
    • Excellent interpersonal, verbal, and written communication.
    • Strong organizational skills

    Required Application Materials

    Interested applicants should submit the following materials to CLI-directors@uth.tmc.edu:

    1. A cover letter detailing:
      1. The applicant’s research interests and fit with the position
      2. How their research experience and interests align with one or more active training grants
      3. Citizenship status
    2. Curriculum vitae
    3. Scholarly writing sample
    4. Names and contact information for three references

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

    Ongoing Research Training Grants

    Topic 1: Early Interventions & Assessments

    Possible Mentors: Landry, Zucker, Crawford, Oh, Assel

    Aligned with NCSER’s Early Intervention and Early Learning in Special Education topic, these projects focus on early interventions for children with or at risk for disabilities.

    Expansion of the CIRCLE Progress Monitoring (CPM) System. A measurement grant funded by the Brown Foundation and our SEA supports the development of reliable and valid screening assessments used for moving children ages 3-7 to higher tiers in Response to Intervention models. CLI has developed the CPM for grades pre-k and kindergarten and they are used to assess over 263,400 students per year. Past measurement work on the CPM involved collaboration between CLI and the Texas Education Agency and was funded by the U.S. Department of Education. This project is directed by Dr. Susan Landry and Co-Is include Drs. Assel leading item development and Dr. Montroy examining psychometric properties of the final item pool. The current focus is expansion of the language and literacy subtests of CPM to Grade 1. Our next steps are to add STEM measures to Grade 1 and seek funding for development of aligned pre-k to Grade 5 measures that are available at low cost. Fellows can participate in the continued expansion of this measure to: (a) include multiple progress monitoring timepoints, and (b) to more fully address appropriate screening of students with various special needs conditions.

    Development of Reading RULES!: A Development and Innovation project funded by IES (R305A180094) seeks to iteratively develop and pilot test an innovative kindergarten literacy program. Specifically, this project aims to develop a Tier 2 small-group intervention in decoding, writing, and listening comprehension for kindergarten children at risk for serious reading difficulties. Eligible students are identified with screening measures; then curriculum-based measures (CBM) are used to place children at the appropriate point in the curriculum sequence. This project is directed by Drs. Tricia Zucker and Colby Hall and will be in the pilot study stage when the proposed training program begins. The larger Reading RULES! Program has been the subject of two other IES studies (R324A100129; R324A180221) and was developed at CLI. Fellows on this project can participate in: (a) a RPP where research staff are embedded in a school district using qualitative and quantitative data to inform the development process; (b) the final stages of the pilot study and interpretation of findings to guide final revisions to the intervention; (c) adaptations of the larger Reading RULES! Program to include computerized CBM tests that guide teachers more precisely in placing students in the curriculum sequence.

    Pre-K Home and Classroom Interventions for Spanish-Speaking English Learners. This initial efficacy study focuses on language development and is funded by IES within the Early Learning Programs & Policies topic. Young English learners (ELs) living in poverty are at risk for later reading difficulties and are less likely than their peers to encounter the level of responsive, extended conversations in their homes and preschools needed for school readiness. Furthermore, many types of dual language programs in U.S. schools operate in ways that delay regular exposure to English until later grades, rather than systematically teaching in ways that build on students’ knowledge of their home language to accelerate English proficiency. The proposed project will evaluate a dual-language approach that: a) maintains and improves the home language of DLLs who speak mostly Spanish in their homes via parent coaching, and b) simultaneously coaches teachers to use an explicit cross-language transfer approach in which sophisticated concepts are introduced in Spanish before English. The expected outcome of this project is increased understanding of effective classroom instruction and family engagement approaches for DLLs’ at risk of later reading difficulties. The research sample will include 90 pre-kindergarten (pre-k) classrooms that use a dual language model called Transitional Bilingual in which 90% of pre-k instruction is in Spanish and 10% is in English. A sample of 720 Tier 2 eligible children and their families within these classrooms will participate. Eligible 4-year-old children will meet screening criterion and speak Spanish at home. We expect almost all Hispanic or Latino participants. The primary child outcomes include Spanish and English oral language measures as well as secondary benefits for executive function and social-behavioral outcomes.

    Topic 2: Scalable Professional Development (PD) for Educators Possible

    Mentors: Zucker, Crawford, Landry

    Aligned with NCSER’s Professional Development for Educators topic, these projects evaluate PD approaches for inclusion classroom teachers of young children with or at risk for disabilities.

    Developing Talkers: Building Effective Teachers: This initial efficacy study is funded by IES and directed by Dr. Tricia Zucker. Researchers will evaluate the impact of two theoretically distinct versions of an intervention called Developing Talkers that uses a multi-tiered system of support. PD is designed to improve teacher facilitation of academic language skills and the academic language skills of kindergarten students. The two versions are the Scripted Approach and the Teacher-Inspired Approach. Researchers will monitor teacher uptake of evidence-based practices during a first stage of intervention. At the second stage, researchers will provide additional individualized professional development (PD) resources based on teacher performance using a Sequential Multiple Assignment Randomized Trial (SMART) design. Researchers will explore aspects of teacher cognition, such as memory and vocabulary and other behavioral factors, including, self-efficacy and social norms, that may explain changes in teacher knowledge and behavior. Fellows can participate in: (a) analysis of profiles of teachers’ cognitive and non-cognitive traits associated with uptake of evidence-based practices, or (b) use mixed methods approaches to understand how scripted versus teacher-inspired approaches impact teachers’ approaches to PD/learning and instruction.

    Continuous Improvement for Teachers: This is an initial efficacy study funded by IES (R305A180406) and directed by Dr. April Crawford. In this replication study, researchers will implement three contrasting professional development approaches (guided self-study, facilitated professional learning communities, and remote coaching) of the Texas School Ready! (TSR) PD model. TSR is embedded in 25 community-based lead agents across Texas. By testing the efficacy of the intervention in 440 classrooms with contrasting PD approaches, researchers will identify cost-effective approaches that maximize impact while also taking into account local needs and constraints. Key outcomes include pre-k teachers' beliefs, knowledge, and instructional practices and children's academic and social skills. Fellows can participate in: (a) mixed methods studies of participant’s videotaped instructional activities and responses to guided reflection prompts; (b) analysis of detailed fidelity data (e.g., coach responsiveness ratings, teachers’ online module component usage) to understand components for success.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Pediatrics - Pediatric Research Center

    Postdoc Position Available

    Department of Pediatrics, McGovern Medical School, Houston, TX

    A postdoc position is immediately available. We are studying (1) how growth factor signaling regulates proper craniofacial skeletal development and (2) how altered growth factor signaling leads to develop the heterotopic ossification. We employ multiple approaches including mouse genetics and sophisticated imaging techniques to define the molecular etiology for both craniofacial skeletal defects and heterotopic bone formation.

    Applicants with a Ph.D., D.D.S. / Ph.D., M.D. /Ph.D. or equivalent and a strong background on Developmental Biology, Cell Biology, Molecular Biology and/or Stem Cell Biology are highly encouraged to apply.

    Please send your CV, cover letter indicating current and future research interests, and the name/email address of three references to:

    Yoshihiro Komatsu, Ph.D.

    Associate Professor Department of Pediatrics

    The University of Texas Medical School at Houston

    6431 Fannin St, Houston, TX 77030

    Email: Yoshihiro.Komatsu@uth.tmc.edu

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Pediatrics - Postdoctoral Fellow Position in Cardiovascular Research

    Postdoctoral Associate Position in the Wang Lab

    A postdoctoral position immediately available to work on cardiovascular study at Department of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston. Ph.D. and/or M.D. degree or equivalent in a relevant research area is required. Highly motivated individuals are encouraged to apply, especially candidates that are capable and independent to conquer ‘challenges’ and seek novel discoveries. Studies need background in molecular cell biology and/or biochemistry. Prior experience with mouse genetics or stem cells/iPSCs or bioinformatics is valuable but not required.

    Wang lab research is aimed at understanding molecular and genetic regulations of cardiovascular and craniofacial development, diseases and regeneration. The research approaches in lab include a combination of genetic mouse models, molecular and biochemical techniques, electrophysiology studies, imaging techniques, genomics, proteomics, and next generation sequencing techniques. Candidate’s study will need to use mouse genetics, cell culture and manipulation, electrophysiology studies, molecular biological and biochemical techniques such as immunofluorescence and CRISPR-Cas9 genome editing, as well as sequencing techniques such as scRNA-seq, Cut-Tag seq and ATAC-seq. Candidate’s study will also involve development of new methods, and collaborations with physicians and different research groups that are expertise in bioinformatics, neural science and biochemistry. Candidate is expected to be collaborative and have good oral & written communication skills.

    McGovern Medical School, The University of Texas Health Science Center at Houston has exceptional resources in biomedical research. McGovern Medical School is located in the heart of the Texas Medical Center, the largest medical complex in the world, providing an outstanding environment for innovation. Researchers collaborate across institutions creating a vast biomedical research ecosystem. Houston, the fourth most populous city in the United States, has a modest cost of living and is family friendly.  

    Salary will follow NIH guideline depending on experience. Candidate will also have opportunities to apply for research fund and fellowships. Applicants should send a cover letter briefly describing your research interests and future goals, curriculum vitae, and contact information for three references to Dr. Jun Wang (email: jun.wang@uth.tmc.edu)

    URL to a full list of published work in My Bibliography:

    http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/43201576/?sort=date&direction=descending

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Pediatrics- Kidney Development

    Postdoc Position in Kidney Development

    We are seeking a highly motivated, organized and enthusiastic postdoctoral fellow to study embryonic kidney development and its relationship to developmental kidney diseases. We are interested in the role of Wnt signaling in shaping nephric tubules, utilizing Xenopus (frog) embryos and mammalian tissue culture as models. Current goals include: 1) Determining how junctions are formed during tubule formation; 2) Modeling how patient mutations result in human developmental kidney diseases; 3) Discovering novel components affecting nephron development; 4) Visualizing in vivo tube formation using advanced live imaging techniques; 5) Generating transgenic animals to visualize nephrogenesis in vivo.

    Current projects utilize developmental, molecular and cell biological approaches including imaging in living embryos. Applicants with a Ph.D., M.D. or equivalent and a strong background in Developmental Biology, Embryology, Cell Biology, Molecular Biology and/or Stem Cell Biology are highly encouraged to apply. Salary and benefits are commensurate with relevant experience. Review of applications will continue until the position has been filled.

    Please send your CV, cover letter indicating current and future research interests, and the name/email address of three references to:

    Rachel K. Miller, Ph.D.

    Department of Pediatrics

    The University of Texas Medical School at Houston

    Email: Rachel.K.Miller@uth.tmc.edu

    https://med.uth.edu/pediatrics/miller-lab/

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Pediatrics: Infectious Diseases- Clonal Emergence and Mechanisms of Pathogenesis in Streptococci

    Postdoctoral research positions (2) are available in the laboratory of Dr. Anthony R. Flores in the Division of Infectious Diseases, Department of Pediatrics at the UTHealth McGovern Medical School.  Research within the Flores Laboratory uses a combination of clinical epidemiology, cutting-edge bacterial “omics”, and models of bacterial pathogenesis to uncover novel features of clonal emergence and mechanisms of pathogenesis in streptococci.  Current projects include (1) gene regulatory responses in group A Streptococcus (GAS) to human antimicrobial peptides, (2) two-component system gene regulation and pathogenesis in group B Streptococcus (GBS), and (3) genomic epidemiology of GAS and GBS to detect novel clonal emergence and outbreaks using ongoing clinical strain surveillance.

    Interested applicants should be highly motivated and have or will soon earn a PhD in microbiology, molecular biology, or a related field.  Ideal candidates will also have experience and/or strong interests in bacterial genomics/transcriptomics and bioinformatics. Strong written and oral communication skills are expected.

    Please provide a single PDF file containing (1) a cover letter stating your interests, (2) a brief description of prior research experience, (3) a curriculum vitae, and (4) contact information for 2-3 references to: anthony.r.flores@uth.tmc.edu.

    Salary is commensurate with experience and will follow university/NIH guidelines.  Individuals underrepresented in science and medicine are especially encouraged to apply. Review of applications will begin immediately and continue until both positions are filled.

    For more information:

    https://med.uth.edu/pediatrics/faculty/anthony-r-flores-md-mph-phd/

    https://scholar.google.com/citations?user=A8IF37IAAAAJ&hl=en&oi=ao

    https://www.ncbi.nlm.nih.gov/myncbi/anthony.flores.1/bibliography/public/

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Physical Medicine and Rehabilitation - Neurorehabilitation and Autonomic Dysfunction Research

    Postdoctoral Fellow Neurorehabilitation Research

     Our goal is to improve the lives of those living with spinal cord injury.

    Join a team of experienced rehabilitation researchers with ongoing clinical trials in neuromodulation, neurogenic bladder, autonomic dysfunction, heart rate variability, spasticity, and neuropathic pain in the spinal cord injury (SCI) population, in both the acute and chronic setting.    

    We seek candidates with strong research potential who are highly motivated to conduct and develop systematic research in the domains of neurorehabilitation and autonomic dysfunction.  This is an opportunity for the candidate to develop major research strengths in SCI, clinical trials, neuromodulation, and autonomic dysfunction.  The candidate will have an opportunity to be part of all aspects of clinical trials- from the systematic review and retrospective studies, to the study design and statistical plan, to the IRB submission and pilot trials, and to the eventual grant application for a randomized control trial.  

    Applicants must have a doctoral degree (PhD, MD, MD/PhD) in rehabilitation science, neurophysiology or related area.  Applicants must have experience in human subjects research, data collection, and analyses

    The start date of the fellowship is flexible, but no later than September 1, 2021. Benefits include vacation, sick days, and health care coverage. Salary is commensurate with experience.

    To apply for this 2-3-year postdoctoral fellowship please email your CV, statement of research interests and experience, and contact information for two references to:

    Dr. Argy Stampas

    argyrios.stampas@uth.tmc.edu

    Department of Physical Medicine and Rehabilitation

    McGovern Medical School at UTHealth Houston

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Physical Medicine and Rehabilitation - Neurorehabilitation Research

    Postdoctoral Fellow

    Neurorehabilitation Research

    The NeuroRecovery Research Center at TIRR Memorial Hermann Hospital is seeking a highly motivated researcher to contribute to ongoing projects. The research center is part of Department of Physical Medicine and Rehabilitation (PM&R) at the University of Texas – Medical School at Houston. The research center is house in TIRR Memorial Hermann Hospital that allows easy and convenient access to patient populations, including stroke, spinal cord injury, traumatic brain injury, amputation and pain. TIRR Memorial Hermann Hospital is ranked #3 in Rehabilitation according to US News and World Report.

    A successful candidate must have a doctoral degree (PhD, MD, MD/PhD) in rehabilitation science, rehabilitation engineering, neurophysiology or related areas. The candidate must be highly motivated to advance his/her research career in neurorehabilitation. Proficiency in LabView and MatLab and experience with experimental studies of movement neuroscience are required. Experience with transcranial magnetic stimulation (TMS) or transcranial direct current stimulation (tDCS) in human subjects is desired.

    The post-doctoral fellow is expected to contribute to ongoing projects on neuromodulation for stroke recovery. Development of new projects for possible grant proposal submission and collaboration with other faculty members are strongly encouraged. See our website for details: https://med.uth.edu/pmr/research/

    The position is available immediately. Benefits include vacation, sick days, and health care coverage. Salary is commensurate with experience.

    To apply for this 2-3-year postdoctoral fellowship please email your CV, statement of research interests and experience, and contact information for two references to:

    Sandra Jung

    Sandra.Jung@uth.tmc.edu 

    Department of Physical Medicine and Rehabilitation

    McGovern Medical School at UTHealth Houston

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Psychiatry and Behavioral Science - Mood Spectrum Disorders

    Psychological Intervention and Research Lab for Mood Spectrum Disorders (PIRL-M) Post Doc Fellowship

    The Psychological Intervention and Research Lab for Mood Spectrum Disorders (PIRL-M) is associated with Mood Disorder Excellence Center of the Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences at McGovern Medical School at UT Health. We are dedicated to exploring mechanisms and processes underlying bipolar disorder and recurrent major depression. This also includes discovering and exploring novel integrative treatment approaches for mood disorders, and how mental health professionals approach these new treatments. Some of our work also focuses on the loved ones of individuals experiencing mood disorders.

    The Postdoctoral Fellow will assist Dr. Meyer and PIRL-M in the pursuit of these goals via the following activities: participate in existing research projects but also be involved in the development of new projects, including study design and implementation, manuscript preparation, and grant writing. There will be the option to provide professional psychological services to patients with bipolar disorder and recurrent depression, including assessments and psychosocial treatments.

    Qualifications

    The Postdoctoral Fellow will have completed an APA-accredited Ph.D. or Psy.D. graduate program in clinical psychology, a doctoral internship, and will have their doctoral degree prior to starting in the position. Ideal candidates will have documented interest in mood disorders in adults and expertise in clinical research methods and statistical analysis. Additionally a good foundation in assessment and psychotherapy with mood disorders would be ideal.

    The Postdoctoral Fellowship program will include at least one hour per week of regularly scheduled, face-to-face individual supervision. This supervision is provided by appropriately trained and licensed faculty members. In addition to individual supervision, there are other opportunities for personal development and learning activities, such as didactic trainings, research meetings, and Departmental grand rounds.

    Compensation

    Competitive salary plus generous benefits (including medical insurance, retirement planning, paid holidays and vacation.

    Postdoctoral Fellowship applications

    The DCBI is currently accepting applications on a rolling basis. Please submit a cover letter, CV, and two letters of recommendation to Dr. Thomas Meyer, Director of PIRL-Mat, thomas.d.meyer@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Psychiatry and Behavioral Sciences - Multimodal Neuroimmune Imaging

    Postdoctoral Research Fellow in Neuro-Immune imaging (1.0 FTE): Methods for Analyzing Molecular Neuro-Immune Imaging Data

    Job description

    We are seeking a highly motivated Postdoctoral Research Scientist to investigate methods to process and analyze multimodal neuroimmune imaging data in the human brain. This will develop novel techniques or enhance existing techniques to process/analyze multi-modal datasets that combine data from various imaging modalities including PET imaging (PBR28, ER176, CFN, etc.), ultra-high-field (7T) and/or standard (3T) MR imaging (including resting state, structural T1 & T2, iron density, etc.), and/or plasma inflammatory proteins. The data derives from studies seeking to discover and validate novel bio-signatures of pain in healthy human subjects, subjects that have experienced brain injury, and/or subjects that are awaiting surgery. The researcher will be supervised by Dr. Alan Prossin (and collaborating statisticians/scientists) in the Department of Psychiatry and Behavioral Sciences, McGovern Medical School at UT Health, Houston, TX. This PhD/Post-doc is funded for 1 year by 1 or more grants including Dr. Prossin’s current NIH/NINDS R61/R33 NIH/NINDS grant award as well as other grants on which he collaborates. The starting date is between September and October of 2020. Ideally, the position will involve 1.0 FTE (full-time) research, but we are willing to consider highly focused (and qualified) applicants that are interested in a part time position.

    Qualifications

    We are looking for someone who:

    • holds (or nearly holds) a PhD in Neuroscience, Engineering, Computer Science, Artificial Intelligence, or a related field;
    • is a self-starter
    • takes a strong quantitative, computational view of neuroscience;
    • has strong computer programming skills;
    • takes a practical approach to solving technical problems;
    • has excellent written and spoken English communication skills;
    • has a strong drive for publication;
    • is effective and efficient, able to work within a team, and able to think critically and conceptually.


    The following experience is desirable, but not required:

    • PET and/or MRI data acquisition and analysis;
    • MacOS, scripting within MacOS, networking within MacOS
    • Multi-modal data analysis;
    • proficiency with SPM/MATLAB, R, PMOD, FreeSurfer, FSL
    • iron imaging
    • quantitative analysis of brain connectivity.

    How to Apply:

    Interested applicants should submit the following materials to Dr. Alan Prossin (mailto: Alan.Prossin@uth.tmc.edu, subject: Postdoctoral Fellow):

    • A cover letter detailing the applicant’s clinical and research interests and fit with the program
    • Curriculum Vitae
    • Names and contact information from three references

    Offer

    We offer a temporary position (1.0 FTE) for one year but will consider a part time position for the ideal candidate that cannot commit to a full-time position. Upon a positive performance and availability of funds, the contract may be followed by a period of a further 6-12 months.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Bioinformatics

    Post-Doctoral Research Fellow Position in Biomedical Informatics

    The School of Biomedical Informatics at University of Texas Health Science Center at Houston announces a Post-Doctoral Research Fellow position focusing on biomedical data and knowledge integration/management, big data science, and machine learning approaches applied to health and health behavioral research including cancer research, clinical decision support, and patient communication.

    The position is under the direct supervision of Cui Tao, PhD to support a skilled computer scientist and informatician interested in developing a career in data science applied to biomedical informatics research. The position includes opportunities to receive training in data management, developing machine learning methods to analyze big biomedical data, proposal/paper writing, and developing an independent area of research. The candidate will also have opportunities in working closely with students including co-mentoring graduate/intern students and providing supports in lectures.

    Requirements for this position include having completed a PhD degree preferably from Computer Science, Statistics, biomedical informatics, or Engineering, demonstrated strong quantitative analytic skills including programming skills, and evidence in publishing research article related to biomedical informatics and computer sciences. his position offers a competitive stipend/salary, benefits, office space, and access to internal sources of pilot project support. Candidates should email a current CV and names of at least two references to Cui Tao (Cui.Tao@uth.tmc.edu),

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Biomedical Informatics- Computational Tools to Elucidate Mechanisms of Disease

    School of Biomedical Informatics - Postdoctoral Research Fellow 

    Job description

    UTHealth School of Biomedical Informatics has a postdoctoral research fellow position open. This position focuses on developing bioinformatical and computational tools to address diverse biological questions. Requirements for this position include a doctorate degree and publications in one or more of the following areas: bioinformatics, statistics, mathematics, computer science, cancer biology, and genetics. A strong candidate must be proficient in R and/or Python, has experience working on servers, and has a background in both computation science and biology.

    Our group focuses on understanding the mechanisms behind diseases such as Alzheimer’s and Cancer. The postdoctoral fellow is expected to work on an ongoing or related project. Ongoing research projects includes:

    • Developing computational approaches to discover drug combinations and to repurpose/reposition drugs for Alzheimer's disease treatment and prevention.
    • Inferring cancer evolution (trajectory and timing) using mutational data and identifying biomarkers for treatment efficacy, cancer aggressiveness, and stage estimation.
    • Uncovering chromatin structure aberrations that lead to diseases. These aberrations may be a result of mutations or large-scale CNVs. They may also be a result of epigenomic alterations.
    • Identifying variants involved in altered mRNA processing, including alternative splicing and alternative polyadenylation, in cancer patients and other diseases.

    This postdoctoral researcher will work under the guidance of Jacqueline Chyr, Ph.D.. Salary is based on NIH-pay scale. At this moment, work and meetings are remote. However, candidate must be located in Houston prior to start date.

    To apply for this position, please email a current CV and two letters of recommendation to Jacqueline Chyr, Ph.D. (Jacqueline.chyr@uth.tmc.edu).

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Nursing

    Postdoctoral Research Fellow

    Location: Cizik School of Nursing, The University of Texas Health Science Center at Houston

    Salary: Salary negotiable/based on experience

    Closing Date: Open until filled

    Job Description

    A position is available immediately for a Postdoctoral Research Fellow in the lab of Dr. Diane Santa Maria to study intervention development, planning, piloting, and evaluation of a prevention interventions for youth and young adults experiencing homelessness and unstable housing with a particular focus of HIV/STI and pregnancy outcomes. The candidate will have the ability to publish dissertation papers, experience working on a funded project to develop and pilot test an intervention, opportunities to co-author and lead author resulting papers, and the potential for leading an internally funded, independent research project. Multiple publication opportunities from exist from large cross-sectional, randomized trials, and ecological momentary assessment data sets.

    Appointment

    This position is a full time, 12-month appointment, renewable for 2 years based on funding and performance. Based on performance, this position may result in a tenure track assistant professor position at Cizik School of Nursing.

    Qualifications

    To join our team, we are looking for highly motivated individuals that have demonstrated scientific productivity, excellent verbal and written communication skills, and the capacity to conduct independent research. The candidate must have knowledge of or experience working with high-risk youth or homeless populations. The candidate must be able to work independently, capable of working in the community, designing study protocols, analyzing data, and writing scientific abstracts and manuscripts. Must maintain a flexible schedule including occasional weekend and evening hours.

    Minimum Education/Training Requirements: A doctoral-level degree in Nursing, Public Health, Social Work, Sociology, or Psychology. Focus on adolescent and young adult sexual health and prevention intervention research is preferred.

    Required Knowledge, Skills, And Abilities: Knowledge of high-risk youth or homeless populations and intervention study design. Proficiency with data management and statistical software packages such as REDcap, SPSS, SAS, and STATA. Strong communication skills and cultural competence are essential.

    Physical Capabilities: Requires long periods of sitting and standing and working at a computer. Field work in resource limited settings with high-risk youth will be required. Exerts up to 20 pounds of force occasionally to move objects.

    Work Environment: Office, classroom environment, and frequent community field work site visits. Participation in the UTHealth Postdoctoral Training Program is required.

    To Apply

    Interested applicants send a cover letter describing their background and research interests, CV, representative publication, and contact information for three professional references to: Charmaine Wilson (6901 Bertner Ave., Jane and Robert Cizik School of Nursing, The University of Texas Health Science Center at Houston, TX 77030) by e-mail to: Charmaine.Wilson@uth.tmc.edu.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Public Health - Disease Simulation Models
    The research group of Dr. Ashish Deshmukh at UTHealth is seeking 1 to 2 postdoctoral scholars (funded by the US National Cancer Institute) in clinical decision science, modeling research, cost-effectiveness analysis, and health services research. The primary focus of the fellowship will be on designing disease simulation models of cancers caused by human papillomavirus infection in the US and globally. There will also be opportunities to conduct and contribute to database research, including analyzing national and global cancer registries, national surveillance data, and claims databases. Consideration will also be given to candidates with a background in health data science, data analytics, and health outcomes research. This position also offers fellows an opportunity to develop their own research ideas and programs in related areas in collaboration with the team. They can also submit their own career development grant application with support from Dr. Deshmukh and UTHealth. In addition to the UTHealth team, the fellow will have the opportunity to work closely with stakeholders, including the National Institute of Health, the World Health Organization, and state agencies. Fellow(s) will work closely with Dr. Deshmukh, collaborators (at UTHealth and multiple institutes), postdocs, and GRAs.

    Qualifications:

    Candidate must be a graduate from an accredited doctoral program with a Ph.D. or equivalent degree in industrial engineering, operations research, health services research, health economics, epidemiology, public health, or related quantitative field.

    Competencies:

    Strong work ethic and organization and team-work skills, critical thinking and writing, and knowledge of general-purpose programming languages such as C++, Java, R, or MATLAB is required.

    Required Application Materials: 

    • CV
    • A cover letter describing your experience leading research projects and your postdoctoral goals
    • Contact information for 2-3 references

    Start date:

    Spring/Summer 2021

    Interested candidates should submit their CVs and a detailed cover letter to Dr. Deshmukh, ashish.a.deshmukh@uth.tmc.edu with the subject: "Postdoctoral Fellowship Application."

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Public Health - Epidemiological studies of cardiometabolic & hematological disease traits

    The Department of Epidemiology, Human Genetics and Environmental Sciences at the UTHealth School of Public Health is seeking an exceptional candidate for a post-doctoral fellowship position. This person will have the opportunity to conduct genome-wide association and epidemiological studies of cardiometabolic and hematological disease traits, performing computational analyses and applying or developing novel bioinformatics tools. Resources available for pursuing such research include whole-genome sequencing and other omics datasets available from the Atherosclerosis Risk In Communities Study, Genome Sequencing Program (GSP), Trans-Omics for Precision Medicine (TOPMed) program, and other large-scale biobank studies such as the UK Biobank. Specific research areas will be determined based on the research interests of the candidate. This position will be involved in conducting analyses using existing data from multiple large population-based prospective cohort and case-control studies, writing manuscripts for peer-reviewed publication, reports, and for presentation to academic and community audiences. The candidate will also gain experience in grantsmanship, as well as research design, planning, and execution.

    Candidates must have a Ph.D. or equivalent doctorate in epidemiology, statistical genetics, public health or related disciplines. Preferred skills include epidemiological/statistical approaches, population-based prospective and case-control studies and computational analyses to interpret existing or recently generated omics datasets. Candidates with experience in statistical programming skills in R, SAS or STATA and omics data analysis are strongly encouraged to apply.

    Questions about the position can be directed to zeynep.h.cobanakdemir@uth.tmc.edu. To apply for this position, please email the following documents to Dr. Coban-Akdemir:1) a letter of interest that describes research accomplishments and future research plans, 2) full curriculum vitae, and 3) names and contact information of 2-3 individuals who will provide letters of recommendation if asked.  Review of applications will begin immediately and continue until the position is filled. Starting date is flexible and negotiable.

    Primary duties and responsibilities: 

    1.  Data analysis 40%
    2. Manuscript preparation 40%
    3. Help with grant preparation 10%
    4. Communicating with collaborators and other organizational work related to research 10%

    Required certifications and skills:  

    • Excellent writing skills
    • Good verbal communication skills
    • Epidemiological/statistical approaches
    • Population-based cohort studies
    • Omics datasets analysis

    SECURITY SENSITIVE:  This job class may contain positions that are security sensitive and thereby subject to the provisions of Texas Education Code § 51.215

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Public Health - Epidemiology, Human Genetics, Environmental Science

    Postdoctoral Research Fellow Position - Stanley Scholar

    The UTHealth School of Public Health Department of Epidemiology, Human Genetics and Environmental Sciences seeks a candidate who possesses and demonstrates interest and skills in one of the following topics: (1) population health frameworks and concepts including study design to address specific population health research questions, (2) clinic community-based approaches to mitigate social determinants of health, and (3) data analytics to clarify associations and identify causal inferences in the aforementioned areas.

    The Postdoctoral Research Fellow will work primarily with the faculty at UTHealth School of Public Health and McGovern Medical School: Shreela Sharma, PhD, RD, LD and Thomas Murphy, MD respectively, as well as a team of epidemiologists, statisticians, scholars and practitioners on aspects of design, data collection, statistical analyses, dissemination through publications and presentations, and the development of grant applications.

    The Postdoctoral Research Fellow will contribute to and, in some cases, lead the formulation of population health research questions that are informed by the literature and stakeholder needs; development of study design and/or conduct analyses for: intervention projects designed to improve patient- and population health-level outcomes primarily targeting social determinants of health; collect, analyze and/or interpret qualitative and quantitative data obtained prospectively (e.g. data from electronic medical records, patient surveys) or retrospectively through existing public and private sources to identify determinants of health.

    The applicant may also contribute to on-going grant applications including power analyses, co-author peer –reviewed publications and reports to state and local partners, and present research at national conferences. In addition, applicants will be expected to develop their own grant application, and to develop a manuscript as a first author. We will give preference to candidates with strong applied methodology and statistical skills including analysis of electronic medical record data, experience in population health research, specifically social determinants of health, randomized clinical trials and intervention research methodology and analysis. We are seeking a person who is excited to be part of a dynamic, diverse, and motivated group, and who is driven by a desire to produce both rigorous and policy-relevant research aimed at improving health outcomes.

    Minimum Requirements

    • Applicants must have a Ph.D. in a relevant discipline (e.g., public health, social sciences, biomedical informatics, population health, or another related field).

    • To be competitive for the position, the applicant must have demonstrable knowledge of the structures, performance, quality, policy and environmental context of healthcare to the formulation of solutions to and prevention of population health problems. The application must also demonstrate the ability to design specific population health research questions.

    • Ability to appropriately lead analytic activities for population health research, preparing or reviewing analysis deliverables, data management, and communicating with co-researchers and external stakeholders and representatives.

    • Ability to prepare technical and methodology reports, proposals, and other documentary deliverables

    • Applicants must have demonstrated expertise in one or more statistical packages including STATA, R, SAS, and/or other statistical software.

    • The applicant must have a record of research productivity through publications and presentations.

    • Applicants should be able to work both independently and as a collaborative team member.

    Required Degree

    • Doctorate – PhD in relevant discipline

    Desired Qualifications

    • Interest in population health research

    • Experience working on large scale, team projects

    • Excellent interpersonal, verbal and written communication

    • Strong organizational skills and experience coordinating data management and analysis activities

    Required Application Materials

    Interested applicants should submit the following materials to Dr. Shreela Sharma at Shreela.V.Sharma@uth.tmc.edu and Dr. Thomas Murphy at Thomas.J.Murphy@uth.tmc.edu:

    (1) A cover letter detailing the applicant’s research interests and fit with the position,

    (2) Curriculum vitae

    (3) Scholarly writing sample, and

    (4) Names and contact information for three references.

    The position is for up to one year and the salary will commensurate based on education and experience.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Public Health - Epidemiology, Human Genetics, Environmental Science

    The Division of Epidemiology, Human Genetics and Environmental Sciences at the UTHealth School of Public Health is seeking an exceptional candidate for a post-doctoral fellowship position. This person will have the opportunity to conduct epidemiological studies on a wide range of research topics, including NIH funded studies. Potential research topics include examining the population health effects of sleep deficiency and disruption of diurnal behaviors such as rest and activities, and eating and fasting rhythms; investigating the role of metabolomics in mediating the health impact of unhealthy behaviors, particularly circadian disruption and Alzheimer’s diseases; and studying how neighborhood environment and socioeconomic deprivation shape health behaviors and contribute to health disparities of chronic diseases, including metabolic disorders, obesity and cancer. Specific research areas will be determined based on the research interests of the candidate. This position will be involved in conducting analyses using existing data from multiple large cohort and cross-sectional studies, writing manuscripts for peer-reviewed publication, reports, and for presentation to academic and community audiences. The candidate will also gain experience in grantsmanship, as well as research design, planning, and execution.

    Candidates must have a Ph.D. or equivalent doctorate in public health or related disciplines. Applicants with a doctoral degree in another discipline may be considered if they possess adequate skills to conduct population research. Preferred skills include epidemiological/statistical approaches, population cohort studies and secondary data analyses. Candidates with experience in geographic information system, data analysis using wearable device, and omics are strongly encouraged to apply.

    Questions about the position can be directed to qian.xiao@uth.tmc.edu. To apply for this position, please email the following documents to Dr Xiao: 1) a letter of interest that describes research accomplishments and future research plans, 2) full curriculum vitae, and 3) names and contact information of 2-3 individuals who will provide letters of recommendation if asked. Review of applications will begin immediately and continue until the position is filled. Starting date is flexible and negotiable.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Public Health - Genetic Epidemiology of Chronic Disease Traits

    Postdoctoral Fellow for Genetic Epidemiology of Chronic Disease

    Brownsville Campus of UTHealth School of Public Health

    Position Description and Requirements

    Description/Summary of position: Human genome studies are providing important new insights into chronic diseases such as obesity, diabetes, heart disease and cancer, with opportunities for translation of research findings to clinical and community settings for disease prevention and health promotion.  Yet, there remain an insufficient number of genetic epidemiologists who can design and implement multidisciplinary genetic epidemiology research that combines technological advances in genome measurement with cutting-edge statistical tools to advance understanding of the genomic basis of traits and associated diseases in the most-burdened underserved minority populations. This search for a genetic epidemiologist responds to these research gaps by providing interdisciplinary, integrated, and comprehensive instruction in the genetic epidemiology from an outstanding team of research mentors with expertise spanning four proposed training dimensions: genetic epidemiology; computation/methods; `OMICs; and culture, diversity, and disparities.

    We are therefore offering a postdoctoral research fellowship in the Genetic Epidemiology of chronic disease traits in collaboration with the University of North Carolina at Chapel Hill, and Vanderbilt University in Nashville, Tennessee. The goals are to support the training, career development, and professional growth of the post-doctoral fellow by fostering skills and knowledge in genetic analysis of chronic disease, specifically obesity, diabetes and cardiovascular disease. The post-doctoral fellow will participate with mentors, other faculty and peers in the in the research group authoring publications, making presentations at scientific and/or professional meetings, and developing grant support. Responsibilities of the post-doctoral fellow are to work towards enhancing his/her substantive and methodological skills in the genetics of chronic diseases and related disciplines.

    Educational Requirements:

    A doctoral degree (PhD) in Epidemiology, Human Genetics, Biostatistics, Bioinformatics or related field or a MD, DDS, or DVM degree combined with training in human genetics at the PhD or Master’s levels (or equivalent) is/are required.

    Qualifications and Experience:

    A curriculum vitae reflecting scientific productivity in epidemiology, human genetics, chronic disease phenotypes and/or biomedical sciences is required. Participation in this program requires a commitment of at least 40 hours per week on research and training.

    • Must be conducting research in one of three chronic disease training dimensions: genetic epidemiology (the core training dimension); ‘OMICs; and computation/methods.
    • The individual to be trained must be a citizen or have a valid VISA allowing work in the US.
    • Must be willing to commit two years to the fellowship or adhere to standard NIH payback requirements.
    • Training stipend follows the standard NIH postdoctoral fellowship rates plus a small travel stipend supporting travel each year.
    • Trainee will participate in training activities including attending a monthly genetic epidemiology journal club, genetics seminar, and peer-led workshop.

    Why Brownsville Texas?

    Brownsville Texas is located in the heart of the Rio Grande Valley. It is in the heart of a large Mexican American population with high levels of chronic disease, including obesity, diabetes, heart disease and liver disease.  Brownsville is located in the southern tip of Texas on the Mexico border, and it is a few miles from the Gulf coast town of South Padre Island. It is a tropical climate with a new university and medical school and recently has received Space X as a new and exciting component of the community.  It is a vibrant and young community with a low cost of living.  The opportunities for cutting edge research in this very underserved and understudied population are substantial and the collaboration with expertise in genetic epidemiology is already robust.

    How to apply:

    If you are interested in this post-doctoral fellowship, please submit an application to Joseph B. McCormick (joseph.b.mccormick@uth.tmc.edu) by July 15, 2021 or until filled. The application should include the candidate’s CV and a 1-page document describing a proposed project. Appointments are for one year, with renewal for an additional two years contingent on progress.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • School of Public Health- Epidemiology, Human Genetics and Environmental Sciences

    Postdoctoral Research Fellow Position: Duncan Pediatric Population Health Scholar

    The UTHealth School of Public Health Department of Epidemiology, Human Genetics and Environmental Sciences seeks a candidate who possesses and demonstrates interest and skills in one of the following topics: (1) population health frameworks and concepts including study design to address specific population health research questions affecting children and youth, (2) clinic- community-based approaches to mitigate social determinants of health, and (3) data analytics to clarify associations and identify causal inferences in the aforementioned areas.

    The Postdoctoral Research Fellow will work primarily with the faculty at UTHealth School of Public Health and McGovern Medical School Department of Pediatrics: Shreela Sharma, PhD, RD, LD and Mary E. Aitken, MD, MPH respectively, as well as a team of epidemiologists, statisticians, scholars and practitioners on aspects of design, data collection, statistical analyses, dissemination through publications and presentations, and the development of grant applications. Substantial collaboration with Department of Pediatrics clinical faculty and interaction with clinical and community populations is also envisioned. 

    The Postdoctoral Research Fellow will contribute to and, in some cases, lead the formulation of pediatric population health research questions that are informed by the literature and stakeholder needs; development of study design and/or conduct analyses for: intervention projects designed to improve patient- and population health-level outcomes primarily targeting social determinants of health; collect, analyze and/or interpret qualitative and quantitative data obtained prospectively (e.g. data from electronic medical records, patient surveys) or retrospectively through existing public and private sources to identify determinants of health.

    The applicant may also contribute to on-going grant applications including power analyses, co-author peer –reviewed publications and reports to state and local partners, and present research at national conferences. In addition, applicants will be expected to develop their own grant application, and to develop a manuscript as a first author.

    We will give preference to candidates with strong applied methodology and statistical skills including analysis of electronic medical record data, experience in population health research, specifically social determinants of health, randomized clinical trials and intervention research methodology and analysis. We are seeking a person who is excited to be part of a dynamic, diverse, and motivated group, and who is driven by a desire to produce both rigorous and policy-relevant research aimed at improving health outcomes.

    Minimum Requirements:

    • Applicants must have a Ph.D. in a relevant discipline (e.g., public health, social sciences, biomedical informatics, population health, or another related field).
    • To be competitive for the position, the applicant must have demonstrable knowledge of the structures, performance, quality, policy and environmental context of healthcare to the formulation of solutions to and prevention of population health problems. The application must also demonstrate the ability to design specific population health research questions.
    • Ability to appropriately lead analytic activities for population health research, preparing or reviewing analysis deliverables, data management, and communicating with co- researchers and external stakeholders and representatives.
    • Ability to prepare technical and methodology reports, proposals, and other documentary deliverables.
    • Applicants must have demonstrated expertise in one or more statistical packages including STATA, R, SAS, and/or other statistical software.
    • The applicant must have a record of research productivity through publications and presentations.
    • Applicants should be able to work both independently and as a collaborative team member.

    Required Degree:

    • Doctorate – PhD in relevant discipline.

    Desired Qualifications: 

    • Interest in population health research
    • Experience working on large scale, team projects
    • Excellent interpersonal, verbal and written communication
    • Strong organizational skills and experience coordinating data management and analysis activities.

    Required Application Materials:

    Interested applicants should submit the following materials to Dr. Shreela Sharma at Shreela.V.Sharma@uth.tmc.edu and Dr. Mary Aitken at Mary.E.Aitken@uth.tmc.edu.

    1. A cover letter detailing the applicant’s research interests and fit with the position,
    2. Curriculum vitae
    3. Scholarly writing sample, and
    4. Names and contact information for three references.

    The position is for up to one year and the salary will commensurate based on education and experience.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Translational Biomimetic Bioelectronics Lab: BCI applications & Epilepsy Diagnostic Tools

    Postdoctoral Research Positions in the Translational Biomimetic Bioelectronics Lab (TBBL)

    About TBBL

    Our mission is first-in-human demonstrations of the most advanced bioelectronics for the treatment of neurologic disease. Multiple Postdoctoral Fellow research positions are available in the TBBL at The University of Texas Health Science Center at Houston (UTHealth) ( www.seymourlab.org). We are part of the newly formed Texas Institute for Restorative Neurotechnologies (TIRN).

    Qualifications:

    Applicants must have a Ph.D. in one of the following: biomedical engineering, electrical engineering, or neuroscience. Our highest priority opening is a BCI or animal experimentalist with domain knowledge of machine learning, biophysics, mathematics, and translation. Two current project positions are open: (1) BCI application of novel, patent-pending depth electrode array, and (2) developing a higher resolution epilepsy diagnostic tool. A strong publication record and excellent academic credentials are highly desirable. Experience in first-in-human deployment would be beneficial.

    World Class Environment:

    Fellows will benefit from a close interaction with our collaborating experts in the fields of neurosurgery, neurology, neuroscience, machine learning, materials science, mixed-mode circuits, and system design. Our closest collaborators at UTHealth are neurosurgeons, neurologists, and neuroscientists who offer critical design input for human or primate use. Our lab is also located in the Biosciences Research Collaborative at Rice University and part the Rice Neuroengineering Initiative, thus collaborations are possible with faculty at UTHealth, Rice University, and Baylor College of Medicine. Our front-end fabrication is performed at the Rice Nanofab facility.

    Competitive salary and benefits are offered to qualified candidates. Houston is an exciting and thriving metropolis that is investing heavily in biotechnology.

    Contact:

    John.P.Seymour@uth.tmc.edu

    www.seymourlab.org 

    Associate Professor in Neurosurgery @ UTHealth

    Adjunct Assoc. Professor in Electrical & Computer Engineering @ Rice University

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

  • Translational Cell Therapy/Regenerative Medicine

    Postdoctoral Position in Translational Cell Therapy/Regenerative Medicine

    Preferred Start Date: March 1, 2020

    I’m looking for an innovative and motivated postdoc.

    About me: I’m part of a dynamic, collaborative, interdisciplinary group. We have an accelerated translational pipeline consisting of pre-clinical research, regulatory process development, cGMP manufacturing, clinical trials, and back-to-bench work. We work with academia and industry on diverse projects that are unified by unmet clinical needs that may be addressed using dynamic cell therapy solutions. We have a backlog of projects, manuscripts, and ideas just waiting for someone that wants to publish a lot of papers. We work on TBI, coagulation, microglia, T cells, esophageal replacement, SCI, HD, and more. I need someone flexible, resourceful, and self-motivated to join the team.

    Description

    We are seeking an individual interested in the fields of stem cell biology and inflammation for eventual clinical translation for cell-based therapies. Responsibilities involve exploring immune modulation by stem cells using a variety of quantitative assays in models of traumatic brain injury. The successful candidate will be able to translate in vitro culture systems into mechanisms of efficacy in vivo in a multidisciplinary setting.

    Qualifications

    Applicants with a Ph.D., M.D./Ph.D. or equivalent is required. The ideal candidate should have experience working with primary cell cultures, and proficiency in molecular and cellular biology techniques. Familiarity with immunology, neuroscience, and/or traumatic brain injury is preferred. Applicants must have excellent written and oral communication skills.

    To Apply

    Please send a cover letter indicating current study and future research interests, curriculum vitae/resume to:

    Scott Olson, Ph.D. Assistant Professor

    E-mail: scott.d.olson@uth.tmc.edu

    Check us out at @OlsonCell

    This is a security sensitive position and thereby subject to Education Code §51.215. A background check will be required for the final candidate.

    UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.