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Stroke is a devastating disease with limited treatment options. The major limitation of new therapeutic and diagnostic development is a lack of understanding of the pathophysiology of each type of stroke in human patients. In order to facilitate direct translational research on stroke, a biobank of tissue samples and data from patients with acute cerebrovascular diseases (i.e., the UTHealth Stroke Program Repository) was established in accordance with federal regulations and institutional policies, and in collaboration with the UTHealth Center for Clinical and Translational Sciences (CCTS) Biobank. This biorepository is focused on obtaining tissue samples and associated data from patients with acute cerebrovascular diseases. The repository will allow investigators at UTHealth and collaborators outside UTHealth to conduct translational research on de-identified samples and data obtained from patients with cerebrovascular diseases. The repository is necessary to determine biomarkers and genomic profiles in order to identify new diagnostics, treatment targets, and predictors of disease.
The objective of this project is the development of a stroke research repository to facilitate research to:
We are currently actively collecting samples for both stroke and control population.
We are collecting samples at the time of admission, Day 1, Day 2, Day 7 and Day 30-120. We are also planning to conduct Spleen Ultrasound, and collect craniotomy and CSF samples in patients where it is feasible.
The study is actively enrolling patients that have experienced signs of an ischemic stroke for last 1 month. We also collect patients biographic data on paper CRFs and then transfer onto a computerized database.
We have also renovated our facilities to support this biocore.
We offer samples from patients and controls to our collaborators. The samples we offer are: