The Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq)
ATAC-Seq is a rapid assay of the epigenetic state by enabling identification of open chromatin regions. In the assay, intact nuclei are treated with a hyperactive Tn5 transposase mutant which is able to simultaneously tag the target DNA with sequencing adapters and fragment the DNA in a process termed “tagmentation”. Because of the assay’s speed, simplicity, sensitivity, and applicability to a wide range of sample types, ATAC-Seq has become a commonly used epigenetic assay, and can serve as a gateway to further, more detailed, epigenetic analyses.
Sample submission requirements
| Service | Sample Type | Minium Amount | Minimum Cell Viability |
| ATAC-seq | Cells | 1 million cells per sample | 80% |
Service Workflow
Useful documents
