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Center for Pulmonary and Critical Care Medicine

Our Research

The Center for Pulmonary and Critical Care Medicine (“CPCM”) is a multi-disciplinary research center focused on studying the molecular mechanisms and immunologic responses during acute disease states of the lungs, heart, and kidneys. The CPCM aims to understand basic disease mechanisms and identify novel therapeutic interventions to improve the morbidity and mortality of patients requiring major surgery or critical care medicine. The CPCM is one of several multi-disciplinary, organ-focused research centers within the Institute of Perioperative Medicine at UTHealth Houston.

Vision

The CPCM aspires to be the leader of lung and critical care research within the Texas Medical Center in Houston, in the State of Texas, and to lead innovative and therapy-targeted research in critical care medicine nationally and internationally, including scientific discovery, research training, and transformation of perioperative critical medicine.

Mission

Promote groundbreaking research focused on understanding the underlying disease mechanisms and immunology of acute lung diseases, such as acute respiratory distress syndrome (ARDS) and pneumonia, in addition to sepsis, myocardial injury (MI), and acute kidney injury (AKI). We focus on mechanistic findings that can be employed therapeutically and have the potential to stimulate randomized clinical trials in patients experiencing critical illness. In this regard, we collaborate closely with the Center for Outcomes Research of the Institute of Perioperative Medicine (Director Dr. Turan, senior center member Dr. Sessler) to conduct randomized clinical trials testing novel interventions.

Center Directors

 Holger Eltzschig
MD, PhD
Chair, John P. and Kathrine G. McGovern Distinguished University Chair, Professor, Anesthesiology, Surgery, and Biochemistry, Associate Vice President, Translational Medicine, Director, Center for Perioperative Medicine
 Xiaoyi Yuan
PhD
Associate Professor, Department of Anesthesiology

Core Members

 Wenbo Li
PhD
Associate Professor, Department of Biochemistry and Molecular Biology
 Kuang-Lei Tsai
PhD
Assistant Professor, CPRIT Scholar, Cancer Prevention Research Institute of Texas
 Tingting Mills
PhD
Assistant Professor, Department of Biochemistry and Molecular Biology
 Matthew Harting
MD, MS
William J. Devane Distinguished Professorship, Associate Professor, General & Thoracic Pediatric Surgery, Medical Director, Pediatric ECMO Program, Medical Director, Pediatric Surgery Telemedicine Program, Director, Comprehensive Center for CDH Care
 Tae Jin Lee
PhD
Associate Professor, Department of Neurosurgery

Affiliated Members

 Scott Evans
MD, FCCP, ATSF
Professor, Endowed Chair, Rebecca Meyer Brown and Joseph Mellinger Brown Chair in Basic Science Research, Division of Internal Medicine, Department Chair ad interim, MD Anderson Cancer Center, Department of Pulmonary Medicine
 Marcos Vidal Melo
MD, PhD
Professor and Chair, UTMB, Department of Anesthesiology