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Center for Perioperative Artificial Intelligence Research

With the growing AI force, there is a need to bridge large public health datasets, basic science findings, and clinical research and practice to improve patient care and perioperative outcomes. This Center will leverage data science, informatics, and AI to achieve excellence in perioperative medical research by integrating a team of experts in AI, basic, translational, and clinical research.

Our center aims to become a national leader in AI perioperative medicine research, focusing on understanding the mechanism and developing preventative/treatment strategies for perioperative disease.

Our center will leverage data science, informatics, and artificial intelligence to achieve excellence in perioperative medical research by integrating a team of experts in AI, basic, translational, and clinical research. We aim to develop and apply AI methods and tools to advance health care delivery, biomedical discovery, and public and population health.

Our Research

Over 200 million major surgeries are performed annually, and it is estimated that 1–4% of these patients will die perioperatively. Perioperative death is considered the third leading cause of death in the USA, following heart disease and cancer. Acute perioperative organ injury causing single- or multiple-organ failure is the leading cause of mortality and morbidity in surgical patients. Little is known why a patient develops perioperative organ injury, what are the risk factors, underlying mechanism, preventive or treatment strategies. With the ever-growing AI force, there is a need to bridge the large public health data, basic science findings, clinical research and practice, to improve patient care and perioperative outcome. The Center for Perioperative Artificial Intelligence Research (PAIR) is therefore developed to leverage the growing sophistication of AI technology to bring tangible improvements to the medical field, particularly in perioperative medicine. The center is jointly led by the Department of Anesthesiology, Critical Care, and Pain Medicine at McGovern Medical School and the Department of Health Data Science and AI at the D. Bradley McWilliams School of Biomedical Informatics.

Center Directors

 Yafen Liang
MD
Center Director, Perioperative Artificial Intelligence Research (Clinical Team), Professor, Vice Chair, Clinical Research, Department of Anesthesiology, Critical Care, and Pain Medicine at McGovern Medical School at UTHealth Houston
 Hongfang Liu
PhD
Center Director, Perioperative Artificial Intelligence Research (Healthcare AI Team), Professor, Director of the Center for TEAM-AI at McWilliams Biomedical Informatics at UTHealth Housotn, Vice President of Learning Health System at UTHealth Houston

Core Members

 Alice O'Brien
MD
Professor, Director, Perioperative Informatics, Site Director, Obstetric Anesthesiology, LBJ Hospital, Adjunct Professor, Obstetrics, Gynecology and Reproductive Sciences
 Licong Cui
Ph.D.
Assistant Director, Research Informatics
 Liwei Wang
MD, PhD
Associate Professor
 Luca Giancardo
PhD
Associate Professor at the Center for Precision Health, McWilliams School of Biomedical Informatics at UTHealth Houston
 Sunyang Fu
PhD
Assistant Professor, Department of Clinical and Health Informatics
 Wenjin Zheng
PhD
Professor, Department of Bioinformatics and Systems Medicine
 Xiaoyang Ruan
PhD
Assistant Professor, Department of Health Data Science and Artificial Intelligence
 Jinlian Wang
PhD
Assistant Professor, Department of Bioinformatics and Systems Medicine
 Serena Dasani
MD
Assistant Professor, Department of Anesthesiology, Critical Care, and Pain Medicine
 Rishi Kumar
MD, FACC, CMQ
Assistant Professor, Department of Anesthesiology, Critical Care, and Pain Medicine

Affiliated Members

 Alparslan Turan
MD
Professor, Vice Chair - Outcomes Research, Director - Outcomes Research, Assistant President - Translational Research - UTHealth Houston
 Holger Eltzschig
MD, PhD
Chair, John P. and Kathrine G. McGovern Distinguished University Chair, Professor, Anesthesiology, Surgery, and Biochemistry, Associate Vice President, Translational Medicine, Director, Center for Perioperative Medicine
 Cynthia Ju
PhD
Professor, Vice Chair for Research, Joseph C. Gabel, M.D. Endowed Chair in Anesthesiology
 Paul Potnuru
MD
Associate Professor
 Xiaoyi Yuan
PhD
Associate Professor, Department of Anesthesiology